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opencc-by-4.0Dec 2020View details →

Medicinal properties of Morus alba for the control of type 2 diabetes mellitus: a systematic review

Background: the objective of this review was to evaluate the medicinal potential of Morus alba leaves on the control of Type 2 Diabetes Mellitus (DM2). Research question: what is the medicinal potential of Morus alba leaves in the control of DM2? Methods: It was based on the PRISMA Declaration. The included studies were extracted from Scopus, Pubmed, ScienceDirect, Scielo, and Google Scholar; January 2015 to July 2021, Key search terms were MeSH and DeCS: Morus alba, mulberry, hypoglycemic agent. The inclusion criteria were: studies in rats administered Morus alba leaf extracts; studies that included the dimensions of lipidemia and glycemia; studies that included indicators such as fasting glucose, postprandial glucose, glycosylated hemoglobin, triglycerides, low-density lipoproteins, total cholesterol, and insulin resistance. Exclusion criteria: studies in which Morus alba leaves were administered with other plants; studies with other parts of the Morus alba plant; proteomic studies, cancer, duplicate studies, in vitro studies, and evaluation of included studies. All included investigations were evaluated for biases. Results: The extracts of Morus alba leaves at the phytochemical level improve glucose uptake. Chlorogenic acid, isoquercitrin, and quercitrin, present in the leaves of Morus alba have hypoglycemic properties and an ameliorating effect on diabetic nephropathy. This leaf has pharmacological effects such as glucose absorption, insulin secretion production, antioxidant and anti-inflammatory agent, antihyperglycemic and antihyperlipidemic activities, and obesity management. Conclusions: Morus alba leaves have pharmacological effects on DM2 that include glucose absorption, production of insulin secretion, antioxidant agent, antihyperglycemic and antihyperlipidemic activities, and obesity control. Beyond these results, there is a lack of studies on the potential and synergistic effects of the components of Morus alba leaves, which limit the possibility of a more effective therapy using the leaves of the plant.

Tunable Resistive Pulse Sensing data of "The impact of storage on extracellular vesicles: a systematic study" experiments

Raw data of Tunable Resistive Pulse Sensing (TRPS) of "The impact of storage on extracellular vesicles: a systematic study" experiments

Flow cytometry data of "The impact of storage on extracellular vesicles: a systematic study" experiments

Flow cytometry raw data acquired for the pubblication of "The impact of storage on extracellular vesicles: a systematic study"

Fig. 175 in Systematics of the checkered beetle subfamily Platynopterinae SPINOLA (Coleoptera Cleridae)

Fig. 175: Geographic distribution of species as noted.

Fig. 174 in Systematics of the checkered beetle subfamily Platynopterinae SPINOLA (Coleoptera Cleridae)

Fig. 174: Geographic distribution of species as noted.

Fig. 173 in Systematics of the checkered beetle subfamily Platynopterinae SPINOLA (Coleoptera Cleridae)

Fig. 173: Geographic distribution of species as noted.

Fig. 176 in Systematics of the checkered beetle subfamily Platynopterinae SPINOLA (Coleoptera Cleridae)

Fig. 176: Geographic distribution of Tarandocerus lycoides.

Fig. 177 in Systematics of the checkered beetle subfamily Platynopterinae SPINOLA (Coleoptera Cleridae)

Fig. 177: Proposed phylogeny of genera of Platynopterinae.

How are software repositories mined? A systematic literature review of workflows, methodologies, reproducibility, and tools

This is the excel spreadsheet dataset containing our analysis of papers performing mining software repositories research from the conferences ICSE, ESEC/FSE, and MSR from the years 2018 - 2020. The data is broken into columns and can be explained at a high-level as follows: Column      Content 1                 The paper being analyzed 2                 Does the paper state the data they analyzed is available 3                 Does the paper perform some sort of data analysis or sampling using data others have compiled in the past 4                 Does the paper state a timestamp for when they begin their work 5                 Does the paper state the use of systems pre-built to help with MSR work 6 - 18          Forms of sampling researchers may have employed to select their data 19               What datasets (if any) were used in the analysis 20               What tools (if any) were used in the analysis 21               How they performed their data sampling workflow 22               How they performed their data filtering workflow 23               How they performed their data retrieval workflow 24               Did they create any scripts in each of these workflows 25 - 33        Did they publish a replication package and what is contained within 34               Is the paper describing a tool for research or not 35               Short description of the paper read 36               A high-level category of the work performed in each paper

opencc-zeroAug 2021View details →

dryad36/100

Temporal and regional trends of antibiotic use in long-term aged care facilities across 39 countries, 1985-2019: systematic review and meta-analysis

Background Antibiotic misuse is a key contributor to antimicrobial resistance and a concern in long-term aged care facilities (LTCFs). Our objectives were to: i) summarise key indicators of systemic antibiotic use and appropriateness of use, and ii) examine temporal and regional variations in antibiotic use, in LTCFs (PROSPERO registration CRD42018107125). Methods & Findings Medline and EMBASE were searched for studies published between 1990-2021 reporting antibiotic use rates in LTCFs. Random effects meta-analysis provided pooled estimates of antibiotic use rates (percentage of residents on an antibiotic on a single day [point prevalence] and over 12 months [period prevalence]; percentage of appropriate prescriptions). Meta-regression examined associations between antibiotic use, year of measurement and region. A total of 90 articles representing 78 studies from 39 countries with data between 1985-2019 were included. Pooled estimates of point prevalence and 12-month period prevalence were 5.2% (95% CI: 3.3-7.9; n=523,171) and 62.0% (95% CI: 54.0-69.3; n=946,127), respectively. Point prevalence varied significantly between regions (Q=224.1, df=7, p<0.001), and ranged from 2.4% (95% CI: 1.7-2.7) in Eastern Europe to 9.0% in the British Isles (95% CI: 7.6-10.5) and Northern Europe (95% CI: 7.7-10.5). Twelve-month period prevalence varied significantly between region (Q=15.1, df-3, p=0.002) and ranged from 53.9% (95% CI: 48.3-59.4) in the British Isles to 68.3% (95% CI: 63.6-72.7) in Australia. Meta-regression found no association between year of measurement and antibiotic use prevalence. The pooled estimate of the percentage of appropriate antibiotic prescriptions was 28.5% (95% CI: 10.3-58.0; n=17,245) as assessed by the McGeer criteria. Year of measurement was associated with decreasing appropriateness of antibiotic use over time (OR: 0.78, 95% CI: 0.67-0.91). The most frequently used antibiotic classes were penicillins (n=44 studies), cephalosporins (n=36), sulphonamides/trimethoprim (n=31), and quinolones (n=28). Conclusions Coordinated efforts focusing on LTCFs are required to address antibiotic misuse in LTCFs. Our analysis provides overall baseline and regional estimates for future monitoring of antibiotic use in LTCFs.

Fig. 58 in Radiation Of Endemic Species Flocks In Ancient Lakes: Systematic Revision Of The Freshwater Shrimp Caridina H. Milne Edwards, 1837 (Crustacea: Decapoda: Atyidae) From The Ancient Lakes Of Sulawesi, Indonesia, With The Description Of Eight New Species

Fig. 58. Distribution of Caridina sarasinorum in Lake Poso.

Fig. 60 in Radiation Of Endemic Species Flocks In Ancient Lakes: Systematic Revision Of The Freshwater Shrimp Caridina H. Milne Edwards, 1837 (Crustacea: Decapoda: Atyidae) From The Ancient Lakes Of Sulawesi, Indonesia, With The Description Of Eight New Species

Fig. 60. Distribution of Caridina schenkeli in the Poso catchment.

Fig. 48 in Radiation Of Endemic Species Flocks In Ancient Lakes: Systematic Revision Of The Freshwater Shrimp Caridina H. Milne Edwards, 1837 (Crustacea: Decapoda: Atyidae) From The Ancient Lakes Of Sulawesi, Indonesia, With The Description Of Eight New Species

Fig. 48. Distribution of Caridina acutirostris in the Poso catchment.

Fig. 20 in Radiation Of Endemic Species Flocks In Ancient Lakes: Systematic Revision Of The Freshwater Shrimp Caridina H. Milne Edwards, 1837 (Crustacea: Decapoda: Atyidae) From The Ancient Lakes Of Sulawesi, Indonesia, With The Description Of Eight New Species

Fig. 20. Distribution of Caridina mahalona in the Malili lake system and the Tomori area.

Fig. 24 in Radiation Of Endemic Species Flocks In Ancient Lakes: Systematic Revision Of The Freshwater Shrimp Caridina H. Milne Edwards, 1837 (Crustacea: Decapoda: Atyidae) From The Ancient Lakes Of Sulawesi, Indonesia, With The Description Of Eight New Species

Fig. 24. Distribution of Caridina masapi in the Malili lake system.

Fig. 27 in Radiation Of Endemic Species Flocks In Ancient Lakes: Systematic Revision Of The Freshwater Shrimp Caridina H. Milne Edwards, 1837 (Crustacea: Decapoda: Atyidae) From The Ancient Lakes Of Sulawesi, Indonesia, With The Description Of Eight New Species

Fig. 27. Distribution of Caridina parvula in the Malili lake system.

Towards Sustainability of Systematic Literature Reviews

Background: The software engineering community has increasingly conducted systematic literature reviews (SLR) as a means to summarize evidence from different studies and bring to light the state of the art of a given research topic. While SLR provide many benefits, they also present several problems with punctual solutions for some of them. However, two main problems still remain: the high time-/effort-consumption nature of SLR and the lack of an effective impact of SLR results in the industry, as initially expected for SLR. Aims: The main goal of this paper is to introduce a new view - which we name Sustainability of SLR - on how to deal with SLR aiming at reducing those problems. Method: We analyzed six reference studies published in the last decade to identify, group, and analyze the SLR problems and their interconnections. Based on such analysis, we proposed the view of  Sustainability of SLR that intends to address these problems. Results: The proposed view encompasses three dimensions (social, economic, and technical) that could become SLR more sustainable in the sense that the four major problems and 31 barriers (i.e., possible causes for those problems) that we identified could be mitigated. Conclusions: The view of Sustainability of SLR intends to change the researchers' mindset to mitigate the inherent SLR problems and, as a consequence, achieve sustainable SLR, i.e., those that consume less time/effort to be conducted and updated with useful results for the industry. _________________________________________________________________________________________________ Summary of files: RAW_DATA.xlsx → contains the raw texts indicating the barriers presented in the paper  Studies_selected.bib → contains references for the published studies selected and used for data extraction.

opencc-by-4.0Sep 2004View details →

Fig. 61 in Morphology, Phylogenetic Taxonomy, And Systematics Of Ichthyornis And Apatornis (Avialae: Ornithurae)

Fig. 61. The number of exemplars of anatomical elements in the YPM Ichthyornis dispar material.

opencc-by-4.0Sep 2004View details →

Fig. 54 in Morphology, Phylogenetic Taxonomy, And Systematics Of Ichthyornis And Apatornis (Avialae: Ornithurae)

Fig. 54. The right ulnare of Ichthyornis dispar (SMM 2503) in (A) anterior and (B) ventral views.