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6,225 results for “expression analysis”
Global gene expression analysis highlights microgravity sensitive key genes in soleus and EDL of 30 days space flown mice
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in physiological condition. The aim of this study was to investigate at both morphological and global gene expression level skeletal muscle adaptation to microgravity in mouse soleus and extensor digitorum longus (EDL). Adult male mice C57BL/N6 were flown aboard the BION-M1 biosatellite for 30 days on orbit (BF) or housed in a replicate flight habitat on Earth (BG) as reference flight control. In this study we investigated for the first time gene expression adaptation to 30 days of microgravity exposure in mouse soleus and EDL highlighting potential new targets for improvement of countermeasures able to ameliorate or even prevent microgravity-induced atrophy in future spaceflights. Overall Design: C57BL/N6 mice were randomly divided in 3 groups: Bion Flown (BF) mice flown aboard the Bion M1 biosatellite in microgravity environment for 30 days; Bion Ground (BG) mice housed in the same habitat of flown animals but exposed to earth gravity; and Flight Control (FC) mice housed in a standard animal facility.
Global gene expression analysis highlights microgravity sensitive key genes in longissimus dorsi and tongue of 30 days space-flown mice
Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study investigated the complexity of the molecular changes in human or mouse paraspinal muscles exposed to microgravity. The aim of this study was to evaluate longissimus dorsi and tongue (as a new potential in-flight negative control) adaptation to microgravity at global gene expression level. C57BL/N6 male mice were flown aboard the BION-M1 biosatellite for 30 days (BF) or housed in a replicate flight habitat on ground (BG). Global gene expression analysis identified 89 transcripts differentially regulated in longissimus dorsi of BF vs. BG mice (False Discovery Rrate < 0,05 and fold change < -2 and > +2) while only a small number of genes were found differentially regulated in tongue muscle ( BF vs. BG = 27 genes). Overall Design: C57BL/N6 mice were randomly divided in 3 groups: Bion Flown (BF) mice flown aboard the Bion M1 biosatellite in microgravity environment for 30 days; Bion Ground (BG) mice housed in the same habitat of flown animals but exposed to earth gravity; and Flight Control (FC) mice housed in a standard animal facility.
A global comparative analysis of gene expression in ovules and leaves based on integrated De Novo transcriptome assembly of Ginkgo biloba L.
GEO Series GSE64502. Ginkgo biloba. 2 samples. Type: Expression profiling by high throughput sequencing.
Differential expression analysis of HFF cells in G0 phase compared to cells in G1 [MAT]
GEO Series GSE36156. Homo sapiens. 14 samples. Type: Expression profiling by genome tiling array.
Global gene expression analysis of vascular progenitors differentiated from human embryonic stem cells or induced pluripotent stem cells and their corresponding donor starting cells
GEO Series GSE44429. Homo sapiens. 16 samples. Type: Expression profiling by array.
Whole transcriptome analysis of unmutated sporadic ALS patients’ peripheral blood reveals phenotype-specific gene expression signature
GEO Series GSE288704. Homo sapiens. 66 samples. Type: Expression profiling by high throughput sequencing.
Renal gene expression analysis: transcript-level data
GEO Series GSE12670. Rattus norvegicus. 48 samples. Type: Expression profiling by array.
Comparative genome-scale analysis of Pichia pastoris variants informs selection of an optimal base strain [protein expression]
GEO Series GSE135665. Komagataella phaffii. 72 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide analysis of gene expression in postnatal hippocampus of Neil1 and Neil2-deficient mice after hypoxia ischemia (HI)
GEO Series GSE236133. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Gene Expression in Perivenous Hepatocytes: A Laser Capture Microdissection and Transcriptomic Analysis.
GEO Series GSE48273. Mus musculus. 9 samples. Type: Expression profiling by array.
Comparative gene expression analysis between Nipponbare and 6-4 under two conditions
GEO Series GSE6187. Oryza sativa Japonica Group; Oryza sativa. 6 samples. Type: Expression profiling by array.
Microarray expression profile and functional analysis of circular RNAs in osteosarcoma
GEO Series GSE96964. Homo sapiens. 8 samples. Type: Non-coding RNA profiling by array.
Transcriptome analysis of differential expressed genes in B cell lymphomas from myeloid-specific Beclin-1 (Becn1ΔM) KO mice compared to (wild type) WT cervical lymph node controls.
GEO Series GSE132899. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Microarray expression profile analysis of lncRNAs in human Pancreatic Ductal Adenocarcinoma
GEO Series GSE130221. Homo sapiens. 12 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Differential gene expression analysis on cells expressing Wild type GFP-MAB21L1 and its mutant form GFP-Arg51Leu and GFP-Arg51Gln
GEO Series GSE166078. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Gene expression analysis of two elite breeding barley lines with distinct tolerance to abiotic stress
GEO Series GSE101962. Hordeum vulgare. 47 samples. Type: Expression profiling by array.
Expression analysis of HFF cells in G0 phase [MAT]
GEO Series GSE36154. Homo sapiens. 14 samples. Type: Expression profiling by genome tiling array.
Analysis of circRNA expression profiles in U937 cells after p62 knockdown
GEO Series GSE220174. Homo sapiens. 2 samples. Type: Non-coding RNA profiling by array.
Expression analysis of mRNA and lncRNA expression levels after shRNA-mediated Myc knockdown in ST486 Burkitt lymphoma cells
GEO Series GSE119923. Homo sapiens. 6 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Expression analysis of INA6 cells after IL-6 withdrawal using MAT
GEO Series GSE29825. Homo sapiens. 14 samples. Type: Expression profiling by genome tiling array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.