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1,052
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ShareScore release 0.9.0
Dataset results
1,052 results for “Cell growth”
Knockdown of NAT12/NAA30 decreases glioblastoma stem cell growth and tumorigenicity by regulating hypoxia response, p-MTOR (Ser2448) and p53 pathway
GEO Series GSE60706. Homo sapiens. 12 samples. Type: Expression profiling by array.
Autophagy Promotes Growth of High Tumor Mutational Burden Tumors by Inhibiting a T Cell Immune Response [RNA-seq]
GEO Series GSE154654. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
PIV data of flow surrounding HEK-293 cell growth
<p>The dataset contains archived data from PIV measurements of flow in an organ-on-a-chip device presented as velocity fields in (yx), as well as cross sections of the data containing dimensions (z) needed to correctly display the data.</p>
The inhibitory effects of Propofol and (-)-Epigallocatechin-3-gallate on the growth of human triple negative breast cancer MDA.MB231 cells.
<p><strong>Figure 1. MDA.MB231 cells migration is inhibiteb by Propofol and EGCG. </strong>MDA.MB231 cells were incubated in medium alone <strong>A); B) </strong>Propofol 10 μg/ml, <strong>C)</strong> EGCG 40 μM , <strong>D)</strong> Propofol 10 μg/ml and EGCG 40 μM. At 48 h <strong>(D)</strong> the inhibitory effect of EGCG and TAP, was clearly evident (*<em>P value</em> < 0.05).</p>
Data from: Resting zone of the growth plate harbors a unique class of skeletal stem cells
Skeletal stem cells regulate bone growth and homeostasis by generating diverse cell types including chondrocytes, osteoblasts and marrow stromal cells. The emerging model postulates a distinct type of skeletal stem cells closely associated with the growth plate1-4, a special cartilaginous tissue playing critical roles in bone elongation5. The resting zone maintains the growth plate by expressing parathyroid hormone-related protein (PTHrP) that interacts with Indian hedgehog (Ihh) released from the hypertrophic zone6-10, while providing a source of other chondrocytes11. However, the identity of skeletal stem cells and how they are maintained in the growth plate are unknown. Here we show that skeletal stem cells are formed among PTHrP+ chondrocytes within the resting zone of the postnatal growth plate. PTHrP+ chondrocytes expressed a panel of markers for skeletal stem/progenitor cells and uniquely possessed the properties as skeletal stem cells in cultured conditions. Cell lineage analysis revealed that PTHrP+ resting chondrocytes continued to form columnar chondrocytes long term, which underwent hypertrophy and became osteoblasts and marrow stromal cells beneath the growth plate. Transit-amplifying chondrocytes in the proliferating zone, which was concertedly maintained by a forward signal from undifferentiated cells (PTHrP) and a reverse signal from hypertrophic cells (Ihh), provided instructive cues to maintain cell fates of PTHrP+ resting chondrocytes. Our findings unravel a unique somatic stem cell type that is initially unipotent and acquires multipotency at the post-mitotic stage, underscoring the malleable nature of the skeletal cell lineage. This system provides a model in which functionally dedicated stem cells and their niche are specified postnatally and maintained throughout tissue growth by a tight feedback regulation system.
Effect of Hydroxyurea Therapy on Growth Parameters in Older Children with Sickle Cell Disease: Low Dose Versus High Dose.
<p>Supplementary Table for a manuscript titled:</p> <p><strong>Effect of Hydroxyurea Therapy on Growth Parameters in Older Children with Sickle Cell Disease: Low Dose Versus High Dose.</strong></p> <p> </p>
Afatinib and Cetuximab in Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Positive Non-small-cell Lung Cancer
ClinicalTrials.gov study NCT03727724. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
A Study of Onartuzumab in Combination With Erlotinib in Patients With MET-Positive Stage IIIB or IV Non-Small Cell Lung Cancer Carrying an Activating Epidermal Growth Factor Receptor (EGFR) Mutation
ClinicalTrials.gov study NCT01887886. IPD Sharing: Not stated. Countries: 8. Publications: 0.
Exercise Controls Tumor Cell Growth Through AMPK Activation
ClinicalTrials.gov study NCT01376583. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study to Compare Furmonertinib to Platinum-Based Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 I
ClinicalTrials.gov study NCT05607550. IPD Sharing: UNDECIDED. Countries: 19. Publications: 0.
Itacitinib in Combination With Erlotinib in Non Small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor (EGFR) Activating Mutations
ClinicalTrials.gov study NCT02355431. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study for Treatment With TH-4000 (Tarloxotinib) in Epidermal Growth Factor Receptor (EGFR) Mutant, T790M-negative Non-small Cell Lung Cancer (NSCLC) Patients
ClinicalTrials.gov study NCT02454842. IPD Sharing: Not stated. Countries: 2. Publications: 0.
An Open Study of ASP8273 in Patients With Non-Small-Cell Lung Cancer (NSCLC) Who Have Epidermal Growth Factor Receptor (EGFR) Mutations
ClinicalTrials.gov study NCT02192697. IPD Sharing: YES. Countries: 3. Publications: 0.
Collection of Blood and/or Bone Marrow for Investigation and Characterization of Normal and Abnormal Cell Growth
ClinicalTrials.gov study NCT01174615. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study of Erlotinib (Tarceva®) in Combination With OSI-906 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With Activating Mutations of the Epidermal Growth Factor Receptor (EGFR) Gene
ClinicalTrials.gov study NCT01221077. IPD Sharing: NO. Countries: 6. Publications: 0.
A Study to Evaluate the Impact of Management Strategies on Gastrointestinal-Related Adverse Events in Participants With Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor (EGFR) Exo
ClinicalTrials.gov study NCT04576208. IPD Sharing: YES. Countries: 0. Publications: 0.
VEGF Signaling Promotes Cell Growth and Metastasis in Extrahepatic Cholangiocarcinoma in a VEGF Receptor Mediated Pathway (ECC)
ClinicalTrials.gov study NCT02103179. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Epidermal Growth Factor Receptor (EGFR) Status Based Gefitinib Neoadjuvant Therapy in Non Small Cell Lung Cancer (NSCLC)
ClinicalTrials.gov study NCT00986284. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Growth Hormone Resistance of Beta-cells in Women and People
ClinicalTrials.gov study NCT06571500. IPD Sharing: NO. Countries: 1. Publications: 0.
Combined Modality Therapy With Growth Factor Support in Locally Advanced Non-small Cell Lung Cancer (NSCLC)
ClinicalTrials.gov study NCT00682383. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.