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520
datasets available to search
ShareScore release 0.9.0
Dataset results
520 results for “Host interactions”
Host-pathogen interactions between Xanthomonas fragariae and its host Fragaria × ananassa investigated with a dual RNA-seq analysis
GEO Series GSE150636. Fragaria x ananassa. 6 samples. Type: Expression profiling by high throughput sequencing.
Global Profiling of the Cellular Alternative RNA Splicing Landscape During Virus-host Interactions
GEO Series GSE81017. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Role of microRNAs in the interaction between Salmonella and the host cell
GEO Series GSE53281. Homo sapiens. 15 samples. Type: Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Expression data from plant tissues during incompatible interaction between the rice host and its major pest, the Asian rice gall midge
GEO Series GSE70526. Oryza sativa. 6 samples. Type: Expression profiling by array.
Spaceflight Analogue Culture Enhances the Host-Pathogen Interaction Between Salmonella and a 3-D Biomimetic Intestinal Co-Culture Model
Physical forces associated with spaceflight and spaceflight analogue culture regulate a wide range of physiological responses by both bacterial and mammalian cells that can impact infection. However, our mechanistic understanding of how these environments regulate host-pathogen interactions in humans is poorly understood. Using a spaceflight analogue low fluid shear culture system, we investigated the effect of Low Shear Modeled Microgravity (LSMMG) culture on the colonization of Salmonella Typhimurium in a 3-D biomimetic model of human colonic epithelium containing macrophages. RNA-seq profiling of stationary phase wild type and delta hfq mutant bacteria alone indicated that LSMMG culture induced global changes in gene expression in both strains and that the RNA-binding protein Hfq played a significant role in regulating the transcriptional response of the pathogen to LSMMG culture. However, a core set of genes important for adhesion, invasion, and motility were commonly induced in both strains. LSMMG culture enhanced the colonization (adherence, invasion and intracellular survival) of Salmonella in this advanced model of intestinal epithelium using a mechanism that was independent of Hfq. Although S. Typhimurium delta hfq mutants are normally defective for invasion when grown as conventional shaking cultures, LSMMG conditions unexpectedly enabled high levels of colonization by an isogenic hfq mutant. In response to infection with either the wild type or mutant, host cells upregulated transcripts involved in inflammation, tissue remodeling, and wound healing during intracellular survival. Interestingly, infection by the hfq mutant led to fewer transcriptional differences between LSMMG- and control-infected host cells relative to infection with the wild type strain. This is the first study to investigate the effect of LSMMG culture on the interaction between S. Typhimurium and a 3-D model of human intestinal tissue. These findings advance our understanding of how physical forces can impact the early stages of human enteric salmonellosis.
Virus-Host Interactions Gets Lousy: P1vir Phage Development Upon Impaired RNA Global Regulation in E. coli Cells
GEO Series GSE262812. Escherichia coli. 16 samples. Type: Expression profiling by high throughput sequencing.
A comprehensive study on the co-culture interaction between endophytic Fusarium and host Sanghuangporus
GEO Series GSE272365. Sanghuangporus vaninii; Fusarium sp.. 12 samples. Type: Expression profiling by high throughput sequencing.
Sequence and dynamics of SARS-CoV-2 host cell interactions inferred from transcriptome analyses
GEO Series GSE217504. Homo sapiens. 33 samples. Type: Expression profiling by high throughput sequencing.
High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing [bulk RNA-Seq]
GEO Series GSE316869. mouse gut metagenome. 4 samples. Type: Expression profiling by high throughput sequencing.
Malaria Host Pathogen Interaction Center Experiment 04R: Host and parasite gene transcript abundances, from whole blood, of Macaca mulatta infected Plasmodium cynomolgi treated with artemether over 7
GEO Series GSE103507. Plasmodium cynomolgi strain B; Macaca mulatta. 33 samples. Type: Expression profiling by high throughput sequencing.
Malaria Host Pathogen Interaction Center Experiment 24: Host and parasite gene transcript abundances, from whole blood, of Macaca mulatta infected Plasmodium cynomolgi B strain treated with artemether
GEO Series GSE104101. Macaca mulatta; Plasmodium cynomolgi strain B. 15 samples. Type: Expression profiling by high throughput sequencing.
Malaria Host Pathogen Interaction Center Experiment 30: Pilot experiment for Macaca mulatta infected with Plasmodium knowlesi Malayan strain sporozoites to produce and integrate measures of acute prim
GEO Series GSE123495. Plasmodium knowlesi; Macaca mulatta. 63 samples. Type: Expression profiling by high throughput sequencing.
Submandibular lymph node, a key battleground for host-Yersinia pestis interaction: A transcriptomic study using non-human primate model
GEO Series GSE101653. Macaca fascicularis; Chlorocebus aethiops; Macaca mulatta. 55 samples. Type: Expression profiling by array.
Host pathogen interaction between Staphylococcus aureus ATCC25923 and murine RAW264.7 macrophage-like cells
GEO Series GSE23538. Staphylococcus aureus; Mus musculus. 8 samples. Type: Expression profiling by array.
Transcriptomic analysis to study interactions between murine host and fungal commensal Candida albicans upon its gastrointestinal colonization
GEO Series GSE274260. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
Host- parasite interaction: Transcriptome responses to parasitism in the silkworm Bombyx mori
GEO Series GSE75520. Bombyx mori. 4 samples. Type: Expression profiling by array.
Accessible Homeostatic Gastric Organoids Reveal Secondary Cell Type-Specific Host-Pathogen Interactions in Helicobacter Pylori Infections
GEO Series GSE255276. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Mucosal immune and stress responses of Neoparamoeba perurans-infected Atlantic salmon (Salmo salar) treated with peracetic acid shed light on the host-parasite-oxidant interactions
GEO Series GSE211350. Salmo salar. 72 samples. Type: Expression profiling by array.
Efficacy of antiviral therapy and host-virus interactions visualized using serial liver sampling with fine-needle aspirates
GEO Series GSE234015. Hepatitis B virus. 12 samples. Type: Other.
Histone lactylation during host–pathogen interaction: An intimate and persistent affair between Pseudomonas aeruginosa quorum-sensing signaling and host lactate
GEO Series GSE302311. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.