Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
7,228
datasets available to search
ShareScore release 0.9.0
Dataset results
7,228 results for “Modules”
Data from: Thermal plasticity in protective wing pigmentation is modulated by genotype and food availability in an insect model of seasonal polyphenism
<p>Phenotypic variation in natural populations results from complex interactions between organisms and their changing environments. The environment shapes both phenotypic frequencies (during adaptation) and organismal phenotypes (through phenotypic plasticity). Developmental plasticity, in particular, refers to the phenomenon whereby an organism's phenotype depends on the environmental conditions during development. It can match phenotype to ecological conditions and help organisms to cope with environmental heterogeneity, including differences between alternating seasons. Experimental studies of developmental plasticity often focus on the impact of individual environmental cues and do not take explicit account of genetic variation. In contrast, natural environments are complex, comprising multiple variables with combined effects that are poorly understood and may vary among genotypes. We investigated the effects of multifactorial environments on the development of the seasonally plastic eyespots of <em>Bicyclus anynana</em> butterflies. Eyespot size depends on developmental temperature and is involved in alternative seasonal strategies for predator avoidance. In nature, both temperature and food availability undergo seasonal fluctuations. However, our understanding of how thermal plasticity in eyespot size varies in response to food availability and across genotypes remains limited. To address this, we investigated the combined effects of temperature (T; two levels: 20°C and 27°C) and food availability (N; two levels: control and limited) during development. We examined their impact on wing and eyespot size in adult males and females from multiple genotypes (G; 28 families). We found evidence of thermal and nutritional plasticity and temperature-by-nutrition interactions (significant TxN) on the size of eyespots in both sexes. Food limitation resulted in relatively smaller eyespots and tempered the effects of temperature. Additionally, we found differences among families for thermal plasticity (significant GxT effects), but not for nutritional plasticity (non-significant GxN effects) nor for the combined effects of temperature and food limitation (non-significant GxTxN effects). Our results reveal the context dependence of thermal plasticity, with the slope of thermal reaction norms varying across genotypes and across nutritional environments. We discuss these results in light of the ecological significance of pigmentation and the value of considering thermal plasticity in studies of the biological impact of climate change.</p>
Dataset for "Multi-model evidence of future tropical Atlantic rainfall change modulated by AMOC decline"
<p>This dataset contains EC-Earth3 experiments used for the paper Multi-model evidence of future tropical Atlantic rainfall change modulated by AMOC decline (G. Cerato, K. Bellomo, R. D'Agostino, J. von Hardenberg, 2024) submitted to <em>Journal of Climate. </em>Data uploaded here allows the user to reproduce the figures related to the EC-Earth3 experiments from the journal article.</p>
"Systematic Identification of Post-Transcriptional Regulatory Modules": preprocessed data
<p>Processed functional genomic data supplementing the paper "<strong>Systematic Identification of Post-Transcriptional Regulatory Modules"</strong></p>
Novel Activation Modulating Sites in a GPCR Identified with a Large-Scale Alchemical Mutation Scan
<p>This dataset contains the starting configurations and mdp files for the alchemical free energy calculations using pmx.<br>The MD parameter files (*.mdp) for the forward reaction (lambda 0 to 1, wt to mutant) and reverse reaction (lambda 1 to 0, mutant to wt) start with f (forward) and r (reverse). Mdp files are available for the energy minimization (em), npt (npt), equilibrium run (equilibrium) and non equilibrium alchemical transition (nonequilibrium). <br>The starting configurations for mutants of the DRD2 receptor can be found in WT7jvr and WT6cm4 for the active and inactive state respectively. Mutant folders are labeled with the residue number and the amino acid it is mutated to.</p>
DATA for: Asgard archaea modulate potential methanogenesis substrates in wetland soil
<p>Data supporting the findings of this study, including the complete genomes of soil-associated Atabeyarchaeia and Freyarchaeia and their in situ metabolic profiles, are available.</p> <p><strong>Asgard archaea modulate potential methanogenesis substrates in wetland soil</strong></p> <p>Luis E. Valentin-Alvarado<sup>1,2,</sup><sup>†</sup>, Kathryn E. Appler<sup>3,</sup><sup>†</sup>, Valerie De Anda<sup>3,4</sup>, Marie C. Schoelmerich<sup>1,</sup><sup>‡</sup>, Jacob<sup> </sup>West-Roberts<sup>5</sup>, Veronika Kivenson<sup>9</sup>, Alexander Crits-Christoph<sup>1,2,</sup><sup>§</sup>, Lynn Ly<sup>6</sup>, Rohan Sachdeva<sup>1</sup>, David F. Savage<sup>1,7</sup>, Brett J. Baker<sup>3,4</sup>, and Jillian F. Banfield<sup>1,4,8,9,</sup>*</p>
Coastal Upwelling Modulates Winds and Air-Sea Fluxes, Impacting Offshore Wind Energy
<p>Model Output supporting the paper "Coastal Upwelling Modulates Winds and Air-Sea Fluxes, Impacting Offshore Wind Energy"</p> <p>The dataset includes four WRF runs, with upwelling (labeled 'operational') and with upwelling removed (labeled 'experimental'). Two of the runs have parameterized wind turbines, labeled "Fitch". </p> <p>This work was supported by NJ Board of Public Utilities. </p> <p> </p>
Surface Plasmon Resonance Biosensor with Anti-Crossing Modulation Readout
Open the record for dataset details and reuse information.
Data from: Structural basis for activation and allosteric modulation of full-length calcium-sensing receptor
<p>Calcium-sensing receptor (CaSR) is a class C G protein-coupled receptor (GPCR) that plays an important role in calcium homeostasis and parathyroid hormone secretion. Here, we present multiple cryo-electron microscopy structures of full-length CaSR in distinct ligand-bound states. Ligands (Ca<sup>2+</sup> and l-tryptophan) bind to the extracellular domain of CaSR and induce large-scale conformational changes, leading to the closure of two heptahelical transmembrane domains (7TMDs) for activation. The positive modulator (evocalcet) and the negative allosteric modulator (NPS-2143) occupy the similar binding pocket in 7TMD. The binding of NPS-2143 causes a considerable rearrangement of two 7TMDs, forming an inactivated TM6/TM6 interface. Moreover, a total of 305 disease-causing missense mutations of CaSR have been mapped to the structure in the active state, creating hotspot maps of five clinical endocrine disorders. Our results provide a structural framework for understanding the activation, allosteric modulation mechanism, and disease therapy for class C GPCRs.</p>
Clust&See3.0 : clustering, module exploration and annotation.
<p><span>Clust&See</span><span>3</span><span>.0 is the novel version of a </span><span>Cytoscape</span><span> app </span><span>that has been developed to </span><span>identify, visualize and manipulate network clusters and modules, newly enriched with functionalities allowing </span><span>custom </span><span>annotation</span><span>s</span><span> of nodes and computation of their statistical enrichment</span><span>s</span><span>. As the wealth of multi-omics data is growing,</span><span> such functionalities are highly valuable for a better understanding of biological module composition</span><span>.</span></p> <p> </p> <ul> <li><span>go_annot.txt : The protein annotation file extracted from Gene Ontology Biological Process database.</span></li> <li><span>HuRI_CC.txt : The network file containing the largest connect component of <span>the </span>human reference interactome network [1]</span></li> </ul> <p><span>[1] <span>Luck K, Kim D-K, Lambourne L, Spirohn K, Begg BE, Bian W, et al. A reference map of the human binary protein interactome. Nature. 2020;580:402–8. </span></span></p>
Foliar phosphorus concentration modulates the defensive mutualism of an endophytic fungus in a perennial host grass
<p>Grasses hosting <em>Epichloë</em> endophytes are protected against herbivores due to the production of various fungal alkaloids. Previous research has found that high foliar phosphorus concentrations reduce the level of the alkaloid ergovaline, thereby reducing the endophyte-mediated herbivore resistance. Yet, the impact of phosphorus on ergovaline biosynthesis versus its influence on endophyte growth and synthesis of other fungal alkaloids remains unresolved. Our objective was to elucidate these relationships. We grew endophyte-symbiotic and non-symbiotic <em>Festuca arundinacea</em> plants and fertilized them with different doses of phosphorus. Later, half of the plants from each treatment were challenged with larvae of the generalist chewing insect <em>Spodoptera frugiperda</em>. We assessed the relationships between foliar phosphorus levels, fungal mycelium, and alkaloid concentrations, as well as their impacts on larvae performance, herbivore-caused damage, and plant biomass. Endophyte mycelial biomass in plant tissue was found to be independent of foliar phosphorus concentration. The alkaloids lolines and peramine showed a linear relationship with mycelial biomass but no correlation with foliar phosphorus. Surprisingly, high ergovaline concentrations were positively associated with an interaction between endophyte mycelial biomass and foliar phosphorus concentration. Although herbivory increased loline concentration, only high concentrations of ergovaline and peramine were related to reduced <em>S. frugiperda</em> larvae weight gain. However, endophyte presence did not reduce herbivory damage to plants. Contrary to expectation, we did not find a negative but a positive association between concentrations of foliar phosphorus and ergovaline alkaloid, through its interaction with endophyte mycelial biomass. Alternatively, our findings suggest that phosphorus plays a crucial role in modulating the <em>Epichloë</em>-mediated defensive mutualism, primarily through its effects on ergovaline rather than on endophyte concentration or production of other alkaloids.</p>
Data for: 3D Graphene Straintronics for Broadband Terahertz Modulation
<p><span>The dataset contains the raw data for the graphene aerogel study, which evaluated the terahertz properties of different graphene aerogels as a function of compressive strain and annealing conditions. The package includes the data and figures for the paper entitled "3D Graphene Straintronics for Broadband Terahertz Modulation", <a href="https://doi.org/10.1002/aelm.202300853">https://doi.org/10.1002/aelm.202300853</a>.</span></p> <p><span> </span></p>
Tuning the electronic properties of Zr UiO-66 through defect-functionalised multivariate modulation
<p>Raw data supporting the article 'Tuning the electronic properties of Zr UiO-66 through defect-functionalised multivariate modulation'.</p>
Electrically -Modulated Photothermal Force Microscopy for Revealing the Chemical Origins of Polarization Switching at the Nanoscale
<p>The data include all display items that are presented in the main manuscrit and supplementray information files.</p>
Data from: Phenotypic selection on an ornamental trait is not modulated by breeding density in a pied flycatcher population
<p>Most studies of phenotypic selection in the wild have focused on morphological and life-history traits and looked at abiotic (climatic) variation as the main driver of selection. Consequently, our knowledge of the effects of biotic environmental variation on phenotypic selection on sexual traits is scarce. Population density can be considered a proxy for the intensity of intra- and inter-sexual competition and could therefore be a key factor influencing the covariation between individual fitness and the expression of sexual traits. Here, we used an individual-based data set from a population of pied flycatchers (<em>Ficedula hypoleuca</em>) monitored over 24 years to analyse the effect of breeding density on phenotypic selection on dorsal plumage colouration, a heritable and sexually selected ornament in males of this species. Using the number of recruits as a fitness proxy, our results show overall stabilizing selection on male dorsal colouration, with intermediate phenotypes being favoured over extremely dark and dull individuals. However, our results did not support the hypothesis that breeding density mediates phenotypic selection on this sexual trait. We discuss the possible role of other biotic factors influencing selection on ornamental plumage.</p>
Raw Picarro L2140i data - Support to "A versatile water vapor generation module for vapor isotope calibration and liquid isotope measurements"
<p>Support data to reproduce Figure 3 - Figure 10 from the article:</p> <p><em>A versatile water vapor generation module for vapor isotope calibration and liquid isotope measurements</em></p> <p>by Hans Christian Steen-Larsen and Daniele Zannoni</p> <p>Accepted in Atmospheric Measurement Techniques on 25/05/2024 (Preprint available at <a href="https://doi.org/10.5194/amt-2023-160" rel="nofollow">https://doi.org/10.5194/amt-2023-160</a>)</p> <p>Figure numbers refer to the final (peer-reviewed and accepted) version of the manuscript.</p> <p>To reproduce the figures, the data can be used in conjunction with the code available at <a href="https://github.com/danielez83/AMT-2023-160" target="_blank" rel="noopener">https://github.com/danielez83/AMT-2023-160 </a>(https://zenodo.org/doi/10.5281/zenodo.12741980)</p> <p><strong>File description</strong></p> <p>Figure numbers are referring to the final (peer-reviewd and accepted) version of the manuscript.</p> <ul> <li>ADEV_BER17k_withmemory_CALIBRATED_R1.csv <ul> <li>Allan Deviation data without removing memory effect, used in FIgure 3</li> </ul> </li> <li>Cal_Pulses_MultiOven_new20230609.csv <ul> <li>Data obtained with the multioven configuration, used in Figure 9</li> </ul> </li> <li>Cal_Pulses_Selector.csv<br> <ul> <li>Data obtained with the VICI selector configuration (only one oven working), used in Figure 9</li> </ul> </li> <li>HKDS2092.zip<br> <ul> <li>Compressed archive of the Picarro L2140i (HKDS2092) raw data.</li> </ul> </li> <li>HKDS2156.zip<br> <ul> <li>Compressed archive of the Picarro L2140i (HKDS2156) raw data.</li> </ul> </li> <li>HKDS2156_IsoWater_20221116_165037.csv<br> <ul> <li>Results of liquid injections with Picarro vaporizer, used in Figure 4 and Figure 10</li> </ul> </li> <li>SP_BER_inj_time.csv <ul> <li>Date and times of injections, used in Figure 4 and Figure 10</li> </ul> </li> <li>Timings_Picarro.xlsx <ul> <li>Excel spreadsheet with time and dates of experiment. It is used as a lookup table to retrieve the raw data correctly</li> </ul> </li> </ul>
Example data for running wrmXpress modules
<p>Example/test datasets for wrmXpress</p> <ul> <li>Motility (96-well plate, individual wells) - <em>Brugia malayi</em> microfilaria: 20210819-p01-NJW_753</li> <li>Motility (96-well plate, whole plate) - <em>Brugia pahangi</em> adults: 20220622-p02-KTR</li> <li>Motility (24-well plate, whole plate) - <em>Brugia pahangi</em> adults: 20220527-p02-KTR</li> <li>Feeding - <em>Caenorhabditis elegans</em> adults: 20210823-p01-KJG_795</li> <li>Worm size - <em>Caenorhabditis elegans</em>: 20220408-p01-MGC_1351</li> <li>Viability (CellTox) - <em>Brugia malayi</em> microfilaria: 20210917-p15-NJW_913</li> <li>Fecundity (with adults) - <em>Schistosoma mansoni</em>: 20220722-p04-JDC_1606</li> <li>Fecundity (without adults) - <em>Schistosoma mansoni</em>: 20220722-p06-JDC_1608</li> <li>Fecundity - <em>Brugia pahangi</em>: 20210906-p01-NJW_857</li> <li>Tracking - <em>Schistosoma mansoni</em> miracidia: 20240307-p01-RVH</li> </ul>
The role of non-native plant species in modulating riverbank erosion: a systematic review - extracted coded articles dataset
<p>Data extraction sheet of code typologies for the review titled: The role of non-native plant species in modulating riverbank erosion: a systematic review. The uploaded csv file contains all the extracted values for each typology. </p>
Figure 3. Describing the sequence of input sensations sent by the system.-Designing a Growing Functional Modules "Artificial Brain"
<p>To design the controller, first of all, the user should click the button “new” on the toolbar to<br> create an empty canvas and to assign it a controller's name, presently “pathfinder”. Then, the first<br> convenient step is to describe the feedback given by the system as a sequence of sensations (see<br> figure 3). The first sensation named “free”, indicates if the vehicle has been able or not to cross the<br> range of obstacles. Each of the next sixteen values is associated to its corresponding proximity<br> sensors that points out the presence of an obstacle. They are given a name beginning with “s”<br> followed by a number. The red color of the last sensation's field indicates that the given name is<br> invalid; presently, because it contains a blank character.</p>
Probabilistic Shaping over Multi-Subcarrier Modulation - LAB Data
<p>Experimental data of long-haul transmission with probabilistic shaping 36QAM and multi-subcarrier 16QAM. Data sets include optical back-to-back (OB2B) and recirculating loop (LOOP) measurements for 1, 4 and 8 subcarriers.</p>
First Version of iMuSciCA 3D Interaction module
<p>A demonstrator video of the the first version of the iMuSciCA 3D music instrument interaction environment.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.