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ShareScore release 0.9.0
Dataset results
480 results for “Respiratory failure”
Empirical Steroids and/or Antifungals in Immunocompromised Patients With Acute Respiratory Failure From Undetermined Etiology: a Multicenter Double-blind Randomized Controlled Trial
ClinicalTrials.gov study NCT04680884. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
HVNI vs NIPPV in Type 2 Respiratory Failure
ClinicalTrials.gov study NCT07065656. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Therapy With High-flow Oxygen by Nasal Cannula vs Noninvasive Ventilation in Patients With Acute Hypoxemic Respiratory Failure: a Crossover Physiologic Study
ClinicalTrials.gov study NCT03865056. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Cardinality Matching Study of Early v.s. Delayed VV ECMO in Severe Respiratory Failure
ClinicalTrials.gov study NCT03981393. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Multicenter National Randomized Controlled Open Label Study Assessing Interest of Non Invasive Ventilation in out-of Hospital Setting During Acute Respiratory Failure in Chronic Obstructive Pulmonary
ClinicalTrials.gov study NCT01626937. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Data Analysis of the Cytokine Adsorption Treatment on Coronavirus Disease-19 (COVID-19) Patients With Respiratory Failure
ClinicalTrials.gov study NCT04422626. IPD Sharing: NO. Countries: 0. Publications: 0.
Cervical Erector Spinae Plane Block for Dyspnea in Acute Respiratory Failure: A Prospective Cohort
ClinicalTrials.gov study NCT07182695. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Influence of Chest X-ray vs. Chest CT Scan on the Management of ICU Patients With Respiratory Failure
ClinicalTrials.gov study NCT07256860. IPD Sharing: Not stated. Countries: 0. Publications: 0.
POCUS and Respiratory Failure Prognosis Based on Diaphragmatic Dysfunction
ClinicalTrials.gov study NCT05869045. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Doppler Ultrasound Renal Arterial Resistive Indices As Predictor Of Multiorgan Failure In Patients With Acute Hypoxic Respiratory Failure Admitted To Respiratory Intensive Care Unit (Cryptic Shock Ind
ClinicalTrials.gov study NCT03897920. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
A Prospective Observational Cohort Study of Awake Prone Position Ventilation Strategy in Patients With Acute Respiratory Failure
ClinicalTrials.gov study NCT05570903. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Effects of HFNC on Moderate and Severe Respiratory Failure Patients
ClinicalTrials.gov study NCT02687074. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Noninvasive Positive Pressure Ventilation Using Helium:Oxygen Versus Air:Oxygen in Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease Patients Exposed to Sulfur Mustard
ClinicalTrials.gov study NCT00515606. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Outcome of Patients Admitted to Pediatric Intensive Care for Acute Respiratory Failure
ClinicalTrials.gov study NCT06470932. IPD Sharing: NO. Countries: 0. Publications: 0.
Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice
GEO Series GSE37080. Mus musculus. 8 samples. Type: Expression profiling by array.
Dataset related to article: "Clusters of Survivors of COVID-19 Associated Acute Respiratory Failure According to Response to Exercise"
<p>We provide the raw data used for the following article:</p> <p>Vitacca, M.; Paneroni, M.; Malovini, A.; Carlucci, A.; Binda, C.; Sanci, V.; Ambrosino, N. Clusters of Survivors of COVID-19 Associated Acute Respiratory Failure According to Response to Exercise. <em>Int. J. Environ. Res. Public Health</em> 2021, 18, 11868.</p> <p><strong>Abstract</strong>: COVID-19 survivors are associated with acute respiratory failure (ARF) and show a high prevalence of impairment in physical performance. The present studied aimed to assess whether we may cluster these individuals according to an exercise test. The presented study is a retrospective analysis of 154 survivors who were admitted to two hospitals of Istituti Clinici Scientifici Maugeri network, Italy. Clinical characteristics, walked distance, heart rate (HR), pulse oximetry (SpO2), dyspnoea, and leg fatigue (Borg scale: Borg-D and Borg-F, respectively) while performing the sixminute walking distance (6MWT) were entered into unsupervised clustering analysis. Multivariate linear regression identified variables that were informative for the set of variables used for cluster definition. Cluster 1 (C1: 86.4% of participants) and Cluster 2 (C2: 13.6%) were identified. Compared to C1, the individuals in C2 were significantly older, showed significantly higher increase in fatigue and in dyspnoea, greater reduction in SpO2, and a lower HRpeak during the test. The need of walking aids, time from admission to acute care hospitals, age, body mass index, endotracheal intubation, baseline HR and baseline Borg-D, and exercise-induced SpO2 change were significantly associated<br> with the variables that were used for cluster definition. Different characteristics and physiological parameters during the 6MWT characterise survivors of COVID-19-associated ARF. These results may help in the management of the long-term effects of the disease.</p>
Dataset related to: "In-Patient Trajectories and Effects of Training in Survivors of COVID-19-Associated Acute Respiratory Failure"
<p>We provide the raw data used for the following article:</p> <p>Vitacca M, Paneroni M, Salvi B, Comini L, Ambrosino N. <strong>In-Patient Trajectories and Effects of Training in Survivors of COVID-19-Associated Acute Respiratory Failure</strong>. Respir Care. 2022 Jun;67(6):657-666. doi: 10.4187/respcare.09808.</p> <p>Abstract</p> <p><strong>Background: </strong>Pulmonary rehabilitation (PR) is useful in survivors of COVID-19-associated acute respiratory failure (ARF). The aim of this retrospective study on in-patient PR was to report rehabilitative trajectories and effects of cycle training.</p> <p><strong>Methods: </strong>According to the Short Physical Performance Battery (SPPB) score at admission (T0), participants were allocated to stage 1 (SPPB < 6), stage 2 (SPPB ≥ 6 and < 10), or stage 3 (SPPB ≥ 10) and performed increasing level of activities from passive exercises to free walking, balance exercises, strength exercises, and tailored cycle-ergometer endurance training. The primary outcome was SPPB. 6-min walk distance (6MWD), Medical Research Council score, Barthel dyspnea index, and rate of subjects able to cycling were also assessed.</p> <p><strong>Results: </strong>Data of 123 participants were analyzed. At T0, 44 (35.8%), 50 (40.6%), and 29 (23.6%) participants were allocated to stages 1-3, respectively. At discharge, participants showed significant improvements in SPPB, independent of the initial stage, 81 (65.8%) improving more than its minimal clinically important difference. At T1, the proportion of participants in stages 1 and 2 decreased, whereas significantly increased in stage 3 (<em>P</em> = .003), (being 9.8%, 33.3%, and 56.9% for stages 1-3, respectively; <em>P</em> <.001). Sixty-nine of 123 participants (56.1%) underwent cycle exercise training. In participants able to perform it, 6MWD improved by 115 (65-240) m and 60 (40-118) m in participants with and without exercise-induced desaturation, respectively, with significant difference between groups (<em>P</em> = .044).</p> <p><strong>Conclusions: </strong>In-patient PR could be tailored and progressively increased to survivors of COVID-19-associated ARF; cycle training was feasible in half of the participants. Benefits were independent of initial stage of physical performance and allowed participants to move from lower to higher levels of activities.</p>
Dataset related to: "Relationship between perceived and neuromuscular fatigue in COPD patients with chronic respiratory failure with long‑term oxygen therapy: a cross‑sectional study"
<p>We provide the raw data used for the following article:</p> <p>Paneroni M, Vitacca M, Comini L, Salvi B, Saleri M, Schena F, Venturelli M. <strong>Relationship between perceived and neuromuscular fatigue in COPD patients with chronic respiratory failure with long-term oxygen therapy: a cross-sectional study</strong>. Eur J Appl Physiol. 2022 Nov;122(11):2403-2416. doi: 10.1007/s00421-022-05021-2.</p> <p>Abstract</p> <p><strong>Purpose: </strong>To evaluate perceived fatigue (PF) and neuromuscular fatigue (NMF) in patients with COPD and chronic respiratory failure (CRF) on long-term oxygen therapy (CRF-COPD group), and the relationships between PF, NMF, patient's characteristics, comparing severe patients with COPD to patients without CRF (COPD group).</p> <p><strong>Methods: </strong>This cross-sectional study compared 19 CRF-COPD patients with 10 COPD patients attending a rehabilitation program. PF was determined by Fatigue Severity Scale (FSS), while dyspnea by the Barthel Dyspnea Index (BDI). We assessed quadriceps NMF via electrical nerve stimulation during and following a Maximal Voluntary Contraction (MVC) detecting changes after a Constant Workload Cycling Test (CWCT) at 80% of the peak power output at exhaustion.</p> <p><strong>Results: </strong>CRF-COPD patients showed higher PF (+ 1.79 of FSS score, p = 0.0052) and dyspnea (+ 21.03 of BDI score, p = 0.0023) than COPD patients. After the fatiguing task and normalization for the total work, there was a similar decrease in the MVC (CRF-COPD -1.5 ± 2.4 vs COPD -1.1 ± 1.2% baseline kJ<sup>-1</sup>, p = 0.5819), in the potentiated resting twitch force (CRF-COPD -2.8 ± 4.7 vs COPD -2.0 ± 3.3% baseline kJ<sup>-1</sup>, p = 0.7481) and in the maximal voluntary activation (CRF-COPD -0.1 ± 3.9 vs COPD -0.9 ± 1.2 -2.0 ± 3.3% baseline kJ<sup>-1</sup>, p = 0.4354). FSS and BDI were closely related (R = 0.5735, p = 0.0011), while no correlation between PF and NMF was found.</p> <p><strong>Conclusion: </strong>Patients with CRF-COPD develop higher levels of perceived fatigue and dyspnea than patients with COPD; while neuromuscular fatigue is similar, suggesting a mismatch between symptoms and neuromuscular dysfunction.</p> <p> </p>
Lack of association between heart period variability asymmetry and respiratory sinus arrhythmia in healthy and chronic heart failure individuals
<p>Dataset from De Maria B, Dalla Vecchia LA, Maestri R, Pinna GD, Parati M, Perego F, Bari V, Cairo B, Gelpi F, La Rovere MT, Porta A. Lack of association between heart period variability asymmetry and respiratory sinus arrhythmia in healthy and chronic heart failure individuals. PLoS One. 2021 Feb 16;16(2):e0247145. doi: 10.1371/journal.pone.0247145. PMID: 33592077; PMCID: PMC7886158.</p> <p>Abstract</p> <p>Temporal asymmetry is a peculiar aspect of heart period (HP) variability (HPV). HPV asymmetry (HPVA) is reduced with aging and pathology, but its origin is not fully elucidated. Given the impact of respiration on HPV resulting in the respiratory sinus arrhythmia (RSA) and the asymmetric shape of the respiratory pattern, a possible link between HPVA and RSA might be expected. In this study we tested the hypothesis that HPVA is significantly associated with RSA and asymmetry of the respiratory rhythm. We studied 42 middle-aged healthy (H) subjects, and 56 chronic heart failure (CHF) patients of whom 26 assigned to the New York Heart Association (NYHA) class II (CHF-II) and 30 to NYHA class III (CHF-III). Electrocardiogram and lung volume were monitored for 8 minutes during spontaneous breathing (SB) and controlled breathing (CB) at 15 breaths/minute. The ratio of inspiratory (INSP) to expiratory (EXP) phases, namely the I/E ratio, and RSA were calculated. HPVA was estimated as the percentage of negative HP variations, traditionally measured via the Porta's index (PI). Departures of PI from 50% indicated HPVA and its significance was tested via surrogate data. We found that RSA increased during CB and I/E ratio was smaller than 1 in all groups and experimental conditions. In H subjects the PI was about 50% during SB and it increased significantly during CB. In both CHF-II and CHF-III groups the PI was about 50% during SB and remained unmodified during CB. The PI was uncorrelated with RSA and I/E ratio regardless of the experimental condition and group. Pooling together data of different experimental conditions did not affect conclusions. Therefore, we conclude that the HPVA cannot be explained by RSA and/or I/E ratio, thus representing a peculiar feature of the cardiac control that can be aroused in middle-aged H individuals via CB.</p>
Respiratory patterns and baroreflex function in heart failure
<p>Dataset to reproduce tables 1, 2 and 3 of the paper "Respiratory patterns and baroreflex function in heart failure" published on Scientific Reports</p>
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OpenNeuro
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