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468
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ShareScore release 0.9.0
Dataset results
468 results for “ferroptosis”
The epitranscriptional factor PCIF1 orchestrates CD8+ T cell ferroptosis and activation to govern anti-tumor immunity
GEO Series GSE254353. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Targeting nucleoporin 214 selectively eliminates leukemia stem cells by inducing ferroptosis [H3K27ac CUT-Tag-seq]
GEO Series GSE302497. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
MYCN mediates cysteine addiction and sensitizes to ferroptosis
GEO Series GSE189174. Homo sapiens. 56 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Btg2 Inhibits the UFMylation of Fmo1 thus Restricting Taurine Synthesis and Exacerbating Ferroptosis in Hepatic Ischemia-Reperfusion Injury in Mice
GEO Series GSE293329. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Daphnetin induces ferroptosis in ovarian cancer by inhibiting NAD(P)H: Quinone oxidoreductase 1 (NQO1)
GEO Series GSE267812. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Targeting nucleoporin 214 selectively eliminates leukemia stem cells by inducing ferroptosis [RNA-seq 3]
GEO Series GSE273647. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
NCOA4-mediated ferritinophagy exacerbates heart failure by releasing free iron to promote GPX4-mediated ferroptosis
<p>Heart failure (HF) is typically characterized by high mortality and disability rates. The pathogenesis of HF is complex and multifactorial,the exact pathophysiology of HF remains to be fully elucidated. In our research group, we have discovered that autophagy is a crucial mechanism underlying the development of heart failure, and abnormal iron metabolism (such as ferroptosis) is closely associated with the occurrence and progression of cardiovascular diseases.Thus, through the construction of a rat model of heart failure following myocardial infarction and an H/R H9C2 cell model, we have conducted studies and found that NCOA4, through the classical autophagy pathway mediated by ATG5/ATG7 and in association with LC3B, plays a role in mediating ferritinophagy, controlling the degradation of ferritin. This modulation regulates the concentrations of cellular free iron and labile iron pool, suppresses GPX4 expression, promotes lipid peroxidation and oxidative stress, induces ferroptosis, and exacerbates the severity of heart failure. Our proposed hypothesis elucidates the mechanisms by which autophagy, NCOA4-mediated ferritinophagy, and GPX4-mediated ferroptosis contribute to the development of heart failure under conditions of myocardial ischemia and hypoxia. It helps reconcile many previously contradictory viewpoints and provides a viable pathway for the treatment of post-myocardial infarction heart failure.</p>
Construction and validation of a prognostic model for colon cancer based on ferroptosis-related lncRNAs
<p>code and supplemental files</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.