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2,009 results for “Disruption”

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geo24/100

A pleiotropic hypoxia-sensitive EPAS1 enhancer is disrupted by adaptive alleles in Tibetans

GEO Series GSE197527. Homo sapiens; Mus musculus. 67 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.

openGEO-OpenNov 2022View details →
geo24/100

Topological demarcation by HMGB2 is disrupted early upon senescence entry and induces CTCF clustering across cell types

GEO Series GSE98448. Homo sapiens. 53 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other.

openGEO-OpenApr 2018View details →
geo24/100

Selective disruption of NRF2-KEAP1 interaction leads to NASH resolution and reduction of liver fibrosis in mice

GEO Series GSE212644. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2022View details →
geo24/100

Disrupted Macrophage Metabolic Reprogramming in Aged Soleus Muscle During Early Recovery following Disuse Atrophy

GEO Series GSE158987. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2021View details →
geo24/100

MicroRNA biogenesis is broadly disrupted by inhibition of the splicing factor SF3B1

GEO Series GSE240904. Homo sapiens. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.

openGEO-OpenJun 2024View details →
geo24/100

Epigenetic identity in AML is mostly dependent on disruption of non-promoter regulatory elements and reveals potentially antagonistic effects of mutations in epigenetic modifiers [mouse]

GEO Series GSE96744. Homo sapiens; Mus musculus. 7 samples. Type: Methylation profiling by high throughput sequencing; Third-party reanalysis.

openGEO-OpenApr 2017View details →
geo24/100

The impact of late gestation circadian disruption, by two weeks of exposure to chronic light dark phase from 5 weeks before expected calving to 3 weeks expected calving, on dairy cattle hepatic and ma

GEO Series GSE168914. Bos taurus. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2021View details →
geo24/100

Persistent JunB Activation in Fibroblasts Disrupts Stem Cell Niche Interactions Enforcing Skin Aging [RNA-seq]

GEO Series GSE180008. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2021View details →
geo24/100

Mutating DDM1 in Physcomitrella patens disrupts DNA methylation with a minute effect on transposon regulation and development

GEO Series GSE198693. Physcomitrium patens. 8 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenMar 2023View details →
geo24/100

Single-Cell multi-omics reveals disrupted gene regulatory landscape and cell differentiation by Wilms tumor-associated ENL mutation in the developing kidney (snATAC-Seq)

GEO Series GSE243868. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo24/100

PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects

GEO Series GSE235866. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2024View details →
geo24/100

Lack of dystrophin disrupts fetal muscle stem cell polarity and commitment during secondary myogenesis

GEO Series GSE274925. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo24/100

IL-4-induced quiescence of resting naïve B cells is disrupted in systemic lupus erythematosus

GEO Series GSE136035. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2022View details →
geo24/100

A Fast Food Diet and Exercise Led to a Disrupted and Pathogenic Methylome in Mouse Liver

GEO Series GSE85772. Mus musculus. 38 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.

openGEO-OpenAug 2017View details →
geo24/100

Single-cell transcriptomics reveals probiotic reversal of neonatal morphine-induced gene disruptions underlying adolescent pain hypersensitivity.

GEO Series GSE298919. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2025View details →
geo24/100

Clonally expanded targetable natural killer-like T cells seed the aged spinal cord to disrupt wound healing

GEO Series GSE275570. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo24/100

Wide-spread disruption of transcription termination in HSV-1 infection: Next generation sequencing of total and newly transcribed (4sU-RNA) RNA from different virus strains and mutant viruses

GEO Series GSE151912. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2020View details →
geo24/100

Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans

GEO Series GSE83243. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2017View details →
geo24/100

Mistimed sleep disrupts circadian regulation of the human blood transcriptome - Heterozygotes

GEO Series GSE82113. Homo sapiens. 23 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2017View details →
geo24/100

Gene expression profiling of cancer cells with genetic disruption of DNA methyltransferases [Agilent-026652]

GEO Series GSE93135. Homo sapiens. 8 samples. Type: Expression profiling by array.

openGEO-OpenJan 2017View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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