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1,427 results for “Heart diseases”
Measurement of the Prevalence of Sensory Integration Disorders in Babies Having Heart Disease Surgery for Transposition of the Great Vessels Before 6 Months of Age
ClinicalTrials.gov study NCT05137873. IPD Sharing: NO. Countries: 1. Publications: 4.
HUDDLE: Heart Health: Understanding & Diagnosing Disease by Leveraging Echocardiograms
ClinicalTrials.gov study NCT05009589. IPD Sharing: NO. Countries: 1. Publications: 1.
Development and Usability Testing of a Progressive WebApp for Women With Heart Disease
ClinicalTrials.gov study NCT03800082. IPD Sharing: NO. Countries: 1. Publications: 1.
Observatory of Pulmonary Arterial Hypertension of Congenital Heart Disease
ClinicalTrials.gov study NCT02260362. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Oxygen Pulse and Its Curve Patterns in Male Patients With Heart Failure and Chronic Obstructive Pulmonary Disease With and in Healthy Men
ClinicalTrials.gov study NCT05189301. IPD Sharing: NO. Countries: 1. Publications: 1.
The Efficacy and Safety of Ginkgo Biloba Dropping Pills in the Treatment of Coronary Heart Disease With Stable Angina Pectoris and Depression
ClinicalTrials.gov study NCT04529148. IPD Sharing: NO. Countries: 1. Publications: 2.
Exploring the link between airway microbiota and coronary heart disease in COPD patients and controls
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A study of gene expression, structure, and contractility of iPSC-Derived Cardiac Myocytes from a family with heart disease due to LMNA mutation
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Data from: Perfusion index in newborns during critical congenital heart disease screening at 24 hours in healthy newborns: retrospective observational study from the United States
Objective: To describe the distribution of Perfusion Index (PI) in asymptomatic newborns at 24 hours of life when screening for Critical Congenital Heart Disease (CCHD) using an automated data selection method. Design: This is a retrospective observational study. Setting: Newborn nursery in a California public hospital with 3500 to 4000 deliveries annually. Methods: We developed an automated program to select the PI values from CCHD screens. Included were term and late preterm infants who were screened for CCHD from November 2013 to January 2014 and from May 2015 to July 2015. PI measurements were downloaded every 2 seconds from the pulse oximeter and median PI were calculated for each oxygen saturation screen in our cohort. Results: We included data from 2768 oxygen saturation screens. Each screen had a median of 29 data points (interquartile range 17 to 49). The median PI in our study cohort was 1.8 (95% confidence interval 1.8 to 1.9) with interquartile range 1.2 to 2.7. The median pre-ductal PI was significantly higher than the median post-ductal (1.9 vs. 1.8, p = 0.03) although this difference may not be clinically significant. Conclusion: Using an automated data selection method, the median PI in asymptomatic newborns at 24 hours of life is 1.8 with a narrow interquartile range of 1.2 to 2.7. This automated data selection method may improve accuracy and precision compared to manual data collection method. Further studies are needed to establish external validity of this automated data selection method and its clinical application for CCHD screening.
Pulse Oximetry as a Tool for Neonatal Screening and Early Diagnosis of Critical Congenital Heart Disease
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Sex-based differences in short and longer term metabolic heart disease_Supplementary Figures
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Result of the correlation between plasma homocysteine and ischemic heart disease in young adult
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ISCHEMIC HEART DISEASES
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Data from: Age of heart disease presentation and dysmorphic nuclei in patients with LMNA mutations
Nuclear shape defects are a distinguishing characteristic in laminopathies, cancers, and other pathologies. Correlating these defects to the symptoms, mechanisms, and progression of disease requires unbiased, quantitative, and high-throughput means of quantifying nuclear morphology. To accomplish this, we developed a method of automatically segmenting fluorescently stained nuclei in 2D microscopy images and then classifying them as normal or dysmorphic based on three geometric features of the nucleus using a package of Matlab codes. As a test case, cultured skin-fibroblast nuclei of individuals possessing LMNA splice-site mutation (c.357-2A>G), LMNA nonsense mutation (c.736 C>T, pQ246X) in exon 4, LMNA missense mutation (c.1003C>T, pR335W) in exon 6, Hutchinson-Gilford Progeria Syndrome, and no LMNA mutations were analyzed. For each cell type, the percentage of dysmorphic nuclei, and other morphological features such as average nuclear area and average eccentricity were obtained. Compared to blind observers, our procedure implemented in Matlab codes possessed similar accuracy to manual counting of dysmorphic nuclei while being significantly more consistent. The automatic quantification of nuclear defects revealed a correlation between in vitro results and age of patients for initial symptom onset. Our results demonstrate the method's utility in experimental studies of diseases affecting nuclear shape through automated, unbiased, and accurate identification of dysmorphic nuclei.
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease (Invitro ArchR Object)
<p>This repo contains invitro ArchR object</p>
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease (Invivo ArchR Object)
<p>This repo contains invivo ArchR object</p>
Hybrid Exercise Program for Heart Disease: Effect on Health and Quality of Life
ClinicalTrials.gov study NCT07130045. IPD Sharing: YES. Countries: 1. Publications: 0.
Disease Management Platform for Heart Failure (DMP-HF)
ClinicalTrials.gov study NCT04782973. IPD Sharing: NO. Countries: 1. Publications: 0.
Nutrition In Preoperative Pediatric Congenital Heart Disease
ClinicalTrials.gov study NCT05457712. IPD Sharing: NO. Countries: 0. Publications: 1.
Red Flags for Cardiac Examination for Early Detection of Congenital Heart Disease
ClinicalTrials.gov study NCT04801251. IPD Sharing: YES. Countries: 0. Publications: 3.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.