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zenodo16/100

Dataset related to article "Contrast imaging techniques to diagnose hepatocellular carcinoma in cirrhotics outside regular surveillance."

<p>I</p> <p>NTRODUCTION AND AIM:</p> <p>The American Association for the Study of the Liver (AASLD) recommends contrast computerized tomography (CT-scan) and magnetic resonance (MRI) to diagnose hepatocellular carcinoma (HCC) arising in cirrhotic patients under semiannual surveillance with abdominal ultrasound (US). A US guided fine needle biopsy (FNB) serves the same purpose in radiologically undiagnosed tumors and incidentally detected nodules in cirrhotics outside surveillance. In this population, we evaluated the performance of radiological diagnosis of HCC according to 2010 AASLD recommendations.</p> <p>MATERIALS AND METHODS:</p> <p>All cirrhotic patients with a liver nodule incidentally detected by US were prospectively investigated with a sequential application of CT-scan/MRI examination and a FNB.</p> <p>RESULTS:</p> <p>Between 2011 and 2015, 94 patients (mean age 67 years) had a liver nodule (total 120) detected by US in the context of histologically confirmed cirrhosis. Mean nodules diameter was 40 (10-160) mm, 87 (73%) &lt;5cm. At histology, 84 (70%) nodules were HCC, 8 (7%) intrahepatic cholangiocarcinoma, 6 (5%) metastases, 2 (2%) neuroendocrine tumors and 20 (16%) benign lesions. Hyperenhancement in arterial phase followed by wash-out in venous phases on at least one radiological technique was demonstrated in 62 nodules (61 HCC, 1 high grade dysplastic nodule), with a specificity of 97% (IC95%: 85-100%), sensitivity 73% (IC95%: 62-81%) and diagnostic accuracy 80%, being 64% for &ge;5cm HCC. Sensitivity of AFP &gt;200ng/mL was 12% (IC95%: 6-23%).</p> <p>CONCLUSION:</p> <p>A single contrast imaging technique showing a typical contrast pattern confidently identifies HCC also in cirrhotic patients with an incidental liver nodule, thereby reducing the need for FNB examinations.</p>

restrictedMar 2020View details →
zenodo16/100

scINRB: single-cell gene expression imputation with network regularization and bulk RNA-seq data

<p>This data set contains simulation data and experimental data.</p> <p>The simulation data set includes simulated data with five different sizes, each of which contains&nbsp;five different dropout rates, generated by Splatter. Each .rds file contains simulated dropout data, true data and bulk data.&nbsp;</p> <p>The experimental data set includes&nbsp;CellBench benchmarking scRNA-seq datasets, ENCODE cell line data, and HCA data.&nbsp;</p>

restrictedcc-by-4.0Jan 2023View details →
zenodo16/100

Data for: "A Neural-Network-Based Convex Regularizer for Inverse Problems"

<p>Data for: &quot;A Neural-Network-Based Convex Regularizer for Inverse Problems&quot;. The corresponding scripts can be accessed on GitHub (https://github.com/axgoujon/convex_ridge_regularizers).</p> <p>The data is organized as follows:</p> <p>- ct_data_sets.tar.gz:&nbsp; contains preprocessed validation (aka calibration) and test sets with:</p> <ul> <li>ground truth images,</li> <li>FBP reconstructions,</li> <li>measurements, for the various settings explored (3 noise levels).</li> </ul> <p>- mri_data_sets.tar.gz:&nbsp;contains preprocessed validation (aka calibration) and test sets with:</p> <ul> <li>subsampling cartesian masks,</li> <li>sensitivity masks,</li> <li>ground truth image,</li> <li>measurements, for the various settings explored: single- and multi-coil MRI, various acceleration rates (2, 4, and 8), synthetic noise, and different image types (fat suppression or not).</li> </ul> <p>For completeness, the code used to generate the preprocessed data from the raw data can be found on the GitHub repository.</p>

restrictedcc-by-4.0Aug 2023View details →
ClinicalTrials.gov16/100

Ventricular Rate Regularization for Improved Quality of Life in Patients With CHF and AF

ClinicalTrials.gov study NCT00583921. IPD Sharing: Not stated. Countries: 0. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov16/100

Test of Digital Breast Tomosynthesis vs. Regular Mammography in Detecting Breast Cancer in Women Undergoing Diagnostic Mammography

ClinicalTrials.gov study NCT00535327. IPD Sharing: Not stated. Countries: 0. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
geo16/100

The Effects of Regular Post-Exercise Cold Water Immersion on DNA methylation in Muscle Following 10-weeks of Strength Training

GEO Series GSE85621. Homo sapiens. 26 samples. Type: Methylation profiling by array.

openGEO-OpenAug 2016View details →
geo12/100

Expression analysis of seeds and seedlings of tomato growing on regular MS medium or MS medium supplemented with Helical multi-walled carbon nanotubes (Helical MWCNTs) in concentration 25 ug/ml

GEO Series GSE70842. Solanum lycopersicum. 12 samples. Type: Expression profiling by array.

openGEO-OpenMay 2016View details →
geo12/100

Expression data from roots and first two leaves of tomato seedlings growing on regular MS medium or MS medium supplemented with multi-wall carbon nanohorns (25 ug/ml)

GEO Series GSE57541. Solanum lycopersicum. 12 samples. Type: Expression profiling by array.

openGEO-OpenJan 2015View details →
geo12/100

Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for the histone modifications H3K27ac and H3K9me3 in liver tissues from MCD and regular chow diet mice

GEO Series GSE266077. Mus musculus. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMay 2024View details →
geo12/100

Changes in adipose tissue microRNA expression across the menstrual cycle in regularly menstruating women: a pilot study.

GEO Series GSE180625. synthetic construct; Homo sapiens. 29 samples. Type: Expression profiling by array.

openGEO-OpenJul 2021View details →
geo12/100

The Effects of Regular Post-Exercise Cold Water Immersion in Muscle Following 10-weeks of Strength Training

GEO Series GSE85636. Homo sapiens. 52 samples. Type: Expression profiling by array; Methylation profiling by array.

openGEO-OpenAug 2016View details →
geo12/100

Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for the histone modifications H3K27ac and H3K9me3 in liver tissues from high fat and regular chow diet mice.

GEO Series GSE226171. Mus musculus. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMay 2023View details →
geo12/100

Expression profile of a parent and ∆lstC strain in regular and high salt conditions

GEO Series GSE56828. Listeria monocytogenes. 12 samples. Type: Expression profiling by array.

openGEO-OpenApr 2014View details →
geo12/100

Epigenitic regular on effect of Hpb-colonized and -trained mice on peritoneal macrophage

GEO Series GSE301337. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2026View details →
geo12/100

Gene expression profiling of MRC-5 cells treated with 100 ug/mL regular-length pristine SWCNTs for 72 h

GEO Series GSE89375. Homo sapiens. 4 samples. Type: Expression profiling by array.

openGEO-OpenNov 2016View details →
geo12/100

Embryonic stem cells differentiated into embryoid bodies. vs cells grown in regular growth conditions

GEO Series GSE10404. Mus musculus. 12 samples. Type: Expression profiling by array.

openGEO-OpenMar 2008View details →
zenodo12/100

Improvement of Sympathovagal Balance by Regular Exercise May Counteract the Ageing Process. A Study by the Analysis of QT Variability

<p>De Maria B, Lucini D, Gois MO, Catai AM, Perego F, Malacarne M, Pagani M, Porta A, Dalla Vecchia LA. Improvement of Sympathovagal Balance by Regular Exercise May Counteract the Ageing Process. A Study by the Analysis of QT Variability. Front Physiol. 2022 Apr 20;13:880250. doi: 10.3389/fphys.2022.880250. PMID: 35514344; PMCID: PMC9065681.</p> <p>Abstract</p> <p>QT interval (QT) variability analysis provides pathophysiological and prognostic information utilized in cardiac and non-cardiac diseases, complementary to those obtained from the analysis of heart period (HP) variability. An increased QT variability has been associated to a higher risk for cardiac events and poorest prognosis. Autonomic cardiovascular adaptation to internal and external challenges, such those occurring in athletes exposed to high levels of physical stress and in ageing could also be deepen by analyzing QT variability, searching for early prognostic signatures. The aim of the study was to analyze the QT variability and cardiac control complexity in a group of middle-aged half-marathon runners at baseline (B) and at a 10-year follow-up (FU). We found that the overall QT variability decreased at FU, despite the inescapable increase in age (52.3 &plusmn; 8.0 years at FU). This change was accompanied by an increase of the HP variability complexity without changes of the QT variability complexity. Of notice, over the years, the group of athletes maintained their regular physical activity by switching to a moderate intensity rather than strenuous. In conclusion, regular and moderate exercise over the years was beneficial for this group of athletes, as reflected by the decreased overall QT variability that is known to be associated to lower cardiovascular risk. The concomitant enhanced cardiac control complexity also suggests a trend opposite to what usually occurs with ageing, resulting in a more flexible cardiac control, typical of younger people.</p>

restrictedJan 2023View details →
geo12/100

Regularity of Chondrocyte Phenotypic Changes Identified by Single-cell Sequencing in vitro

GEO Series GSE270642. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2025View details →
geo12/100

The Effects of Regular Post-Exercise Cold Water Immersion on Gene Expression in Muscle Following 10-weeks of Strength Training

GEO Series GSE85620. Homo sapiens. 26 samples. Type: Expression profiling by array.

openGEO-OpenAug 2016View details →
zenodo8/100

Row data of the publication: Can beta-blockers influence regular daily physical activity?

<p>Raw data</p> <p>BACKGROUND: In hypertension, beta-blockers have a high rate of nonadherence to treatment likely because of fatigue. METHODS: We evaluate daily physical activity and maximal exercise performance in 56 patients with hypertension (grades I-II), with and without beta-blockers (bisoprolol 10 mg or atenolol 100 mg) added to standard treatment; 48 patients completed the study. Study tests were performed after 8 weeks of antihypertensive therapy without beta blockers and after the following 8 weeks with beta-blockers. RESULTS: No significant differences between beta-blockers were observed. At office measurement, beta-blockers decreased heart rate (HR) from 78 +/- 9 to 62 +/- 7 bpm (P &lt; 0.01) and SBP from 133 +/- 13 to 125 +/- 12 mmHg (P &lt; 0.01). No significant changes were observed for DBP. Conversely, at ambulatory pressure monitoring DBP but not SBP decreased with beta-blockers (mean-24-h DBP 77 +/- 8 vs. 74 +/- 7 mmHg, P &lt; 0.01). An overall reduction of daily activities and of estimated kilocalories consumption was observed as measured by a portable armband device. Of note, time with activity more than 3 METS was reduced by beta-blockers from 148.1 (83-201) to 117.9 (82-189) min (P &lt; 0.01). Cardiopulmonary exercise (CPE) showed a preserved exercise performance unaffected by beta-blockers. CONCLUSION: In hypertension, beta-blocker treatment is associated to reduction of daily physical activity but not of maximal exercise performance.</p>

restrictedDec 2022View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

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