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1,324 results for “Soft tissue”
Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III
ClinicalTrials.gov study NCT04865952. IPD Sharing: NO. Countries: 1. Publications: 13.
Data from: Three-dimensional soft tissue preservation revealed in the skin of a non-avian dinosaur
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Data from: Three-dimensionally preserved soft-tissues and calcareous hexactins in a Silurian sponge: implications for early sponge evolution.
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Data from: A new ophiocistioid with soft-tissue preservation from the Silurian Herefordshire Lagerstätte, and the evolution of the holothurian body plan
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A new marrellomorph arthropod from southern Ontario: A rare case of soft tissue preservation on a late Ordovician open marine shelf
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Prevalence, resistance profiles and factors associated with skin and soft-tissue infections at Jinja regional referral hospital: A retrospective study
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Data from: A new ankylosaurine dinosaur from the Judith River Formation of Montana, USA, based on an exceptional skeleton with soft tissue preservation
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Evolutionary biomechanics: hard tissues and soft evidence?
<p>Biomechanical modelling is a powerful tool for quantifying the evolution of functional performance in extinct animals to understand key anatomical innovations and selective pressures driving major evolutionary radiations. However, the fossil record is composed predominantly of hard parts, forcing palaeontologists to reconstruct soft tissue properties in such models. Rarely are these reconstruction approaches validated on extant animals, despite soft tissue properties being highly determinant of functional performance. The extent to which soft tissue reconstructions and biomechanical models accurately predict quantitative or even qualitative patterns in macroevolutionary studies is therefore unknown. Here, we modelled the masticatory system in extant rodents to objectively test the ability of current muscle reconstruction methods to correctly identify quantitative and qualitative differences between macroevolutionary morphotypes. Baseline models generated using measured soft tissue properties yielded differences in muscle proportions, bite force and bone stress expected between extant sciuromorph, myomorph and hystricomorph rodents. However, predictions from models generated using reconstruction methods typically used in fossil studies varied widely from high levels of quantitative accuracy to a failure to correctly capture even relative differences between macroevolutionary morphotypes. Our novel experiment emphasises that correctly reconstructing even qualitative differences between taxa in a macroevolutionary radiation is challenging using current methods. Future studies of fossil taxa should incorporate systematic assessments of reconstruction error into their hypothesis testing and, moreover, seek to expand primary data sets on muscle properties in extant taxa to better inform soft tissue reconstructions in macroevolutionary studies.</p>
Data from: Buoyancy mechanisms limit preservation of coleoid cephalopod soft tissues in Mesozoic Lagerstätten
Coleoid cephalopods are characterized by internalization of their shell, and are divided into the ten-armed Decabrachia (squids and cuttlefish) and the eight-armed Vampyropoda (octopuses and vampire squid). They have a rich fossil record predominantly of the limited biomineralized skeletal elements they possess: arm hooks, statoliths, mouthparts (the buccal mass) and internal shell (gladius or pen), although exquisitely preserved soft tissue coleoids are known from several Lagerstätten worldwide. Recent studies have shown that although morphological similarities between extant decabrachian gladii and fossil examples exist, no known examples of fossil decabrachians are currently known. However, molecular clock data and phylogenetic bracketing suggest that they should be present in Lagerstätten that are rich in vampyropod soft tissue fossils (i.e. Hâkel and Hâdjoula Lagerstätten, Cretaceous, Lebanon). We propose that a hitherto unknown taphonomic bias pertaining to the differing methods of buoyancy control within coleoid groups limits preservation potential. Both negatively and neutrally buoyant decabrachians use chemical buoyancy control (ammonia) whereas vampyropods do not. In the event of rapid burial in an environment conducive to exceptional preservation, ammonia dramatically decreases the ability of the decabrachian carcass to generate the required pH for authigenic calcium phosphate replacement, limiting its preservation potential. Moreover, the greater surface area and comparatively fragile dermis further decrease the potential for fossilization. This taphonomic bias may have contributed to the lack of preserved labile soft-tissues in other cephalopods groups such as the ammonoids.
Data from: A randomised trial comparing the clinical effectiveness of different emergency department healthcare professionals in soft tissue injury management
OBJECTIVE: To evaluate the clinical effectiveness of soft tissue injury management by emergency nurse practitioners (ENPs) and extended scope physiotherapists (ESPs) compared to the routine care provided by doctors in a UK emergency department (ED). DESIGN: Randomised, pragmatic trial of equivalence. SETTING: One adult ED in England. PARTICIPANTS: 372 patients were randomised; 126 to the ESP group, 123 to the ENP group and 123 to the doctor group. Participants were adults (older than 16 years) presenting to the ED with a peripheral soft tissue injury eligible for management by any of the three professional groups. Patients were excluded if they had any of the following: injury greater than 72 hours old; systemic disease; dislocated joints; recent surgery; unable to give informed consent (eg, dementia), open wounds; major deformities; opiate analgesia required; concurrent chest/rib injury; neurovascular deficits and associated fracture. INTERVENTIONS: Patients were randomised to treatment by ESPs, ENPs or routine care provided by doctors (of all grades). MAIN OUTCOME MEASURES: Upper-limb and lower-limb functional scores, quality of life, physical well-being, preference-based health measures and the number of days off work. RESULTS: The clinical outcomes of soft tissue injury treated by ESPs and ENPs in the ED were equivalent to routine care provided by doctors. CONCLUSIONS: As all groups were clinically equivalent it is other factors such as cost, workforce sustainability, service provision and skill mix that become important. This result validates the role of the ENP, which is becoming established as an integral part of minor injuries care, and demonstrates that the ESP should be considered as part of the clinical skill mix without detriment to outcomes. ISRCTN-ISRCTN trials register number 70891354.
Data from: Integrating viscoelastic mass spring dampers into position-based dynamics to simulate soft tissue deformation in real time
We propose a novel method to simulate soft tissue deformation for virtual surgery applications. The method considers the mechanical properties of soft tissue, such as its viscoelasticity, nonlinearity, and incompressibility; its speed, stability, and accuracy also meet the requirements for a surgery simulator. Modifying the traditional equation for mass spring dampers introduces nonlinearity and viscoelasticity into the calculation of elastic force. Then, the elastic force is used in the constraint projection step for naturally reducing constraint potential. The node position is enforced by the combined spring force and constraint conservative force through Newton's second law. We conduct a comparison study of conventional mass spring dampers and position based dynamics (PBD) for our new integrating method. Our approach enables stable, fast, and large step simulation by freely controlling visual effects based on nonlinearity, viscoelasticity and incompressibility. We implement a laparoscopic cholecystectomy simulator to demonstrate the practicality of our method, in which liver and gallbladder deformation can be simulated in real time. Our method is an appropriate choice for the development of real-time virtual surgery applications.
RESULTS OF TREATMENT OF PURULENT SOFT TISSUE DISEASES ON AN OUTPATIENT BASIS
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Fig. 1 in Soft-tissue preservation in the Lower Cambrian linguloid brachiopod from South China
Fig. 1. The lophophore of Lingulellotreta malongensis from the Yu'anshan Member of the Qiongzhusi (Chiungchussu) Formation, Lower Cambrian, China. A. ELI L−0014A, dorsal view of ventral interior, showing lophophore, with a series of definitive filaments, three−dimensionally preserved in a lamina of sediment between valves. B. ELI L−0033, showing paired imprints of brachia and depression of distinctive visceral cavity. C. ELI L−0052A, a specimen strongly compressed, showing lophophore with filaments. D. ELI L−0056A. D1, parallel specimen with straight pedicle strongly compressed, and with paired spiral brachial imprints; D2, details of the brachial imprints of D1. E. ELI L−0073, a lateral oblique view of strongly compressed specimen, showing detail of a hollow brachial tube. F. ELI L−0101, lateral oblique view of the lophophore three−dimensionally preserved in sediment in valves. G. ELI L−0081, a parallel, possible juvenile specimen strongly compressed; note the relatively small brachia. Scale bars 2 mm. See Fig. 2 for some interpretations.
Fig. 8 in Soft-tissue attachment structures and taphonomy of the Middle Triassic nautiloid Germanonautilus
Fig. 8. Orientation of the aperture and body chamber length of Germanonautilus bidorsatus (von Schlotheim, 1820) from the German Muschelkalk and of Recent Nautilus (modified after Saunders and Shapiro 1986).
Fig. 5 in Soft-tissue preservation in the Lower Cambrian linguloid brachiopod from South China
Fig. 5. Lingulellotreta malongensis from the Chengjiang Fauna, reconstruction of the internal morphology based on ELI L−0014 and ELI L−0017, showing disposition of lophophore and digestive tract, and location of measurements indicated in Table. 1. Abbreviations: L, length of the shell; Lb, length of the body; Ll, length of the lophophore; Ls, length of the dorsal valve; Wl, width of the lophophore; Ws, width of the shell. Scale bar 1 mm.
Fig. 4 in Soft-tissue preservation in the Lower Cambrian linguloid brachiopod from South China
Fig. 4. Two linguloid brachiopods, Lingulellotreta malongensis and Lingulella chengjiangensis, from the Yu'anshan Member of the Qiongzhusi (Chiungchussu) Formation, Lower Cambrian, South China. A. Lingulellotreta malongensis, ELL L−0017. A1, photograph of the dorsally and right laterally compressed specimen, showing the interiors, including the digestive system and paired imprints of brachia; A2, explanatory drawing of the same. B. ELI L−0091A, a parallel specimen of Lingulellotreta malongensis, note the faint brachial contour and digestive tract with considerable relief. C. Lingulella chengjiangensis, ELI C−0029. C1, photograph (dorsal view) of dorsal interior, showing the digestive tract with an anterior anus, and with impression of visceral cavity; C2, explanatory drawing of the same. D. Lingulella chengjiangensis, ELI C−0027, anterodorsally compressed specimen, showing the position of the mouth. Scale bars 2 mm.
The Safety and Efficacy of Combined Microwave Ablation During Limb-sparing Surgery in High-risk Soft Tissue Sarcoma Patients
ClinicalTrials.gov study NCT06802510. IPD Sharing: NO. Countries: 1. Publications: 0.
Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas
ClinicalTrials.gov study NCT00881595. IPD Sharing: Not stated. Countries: 0. Publications: 97.
Safety and Efficacy of a Metallic Cannula Versus A Standard Needle for Soft Tissue Augmentation of the Nasolabial Folds
ClinicalTrials.gov study NCT01066026. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction
ClinicalTrials.gov study NCT02844569. IPD Sharing: YES. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.