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505
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ShareScore release 0.9.0
Dataset results
505 results for “carriers”
Fas- and DR3-dependent transcriptome changes in naïve T-cells from EBV carrier during and after acute mononucleosis
GEO Series GSE95126. Homo sapiens. 48 samples. Type: Expression profiling by array.
A copper activated protease regulates photosynthetic soluble electron carriers in cyanobacteria
GEO Series GSE155385. Synechocystis sp. PCC 6803. 18 samples. Type: Expression profiling by high throughput sequencing.
Myoepithelial cell perturbations in BRCA mutation carriers and in DCIS (ductal carcinoma in situ)
GEO Series GSE113795. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing; Third-party reanalysis.
miRNA expression in healthy carriers of heterozygous BRCA1 mutation and healthy WT controls
GEO Series GSE60444. Homo sapiens; Mus musculus; Rattus norvegicus. 21 samples. Type: Non-coding RNA profiling by array.
Dataset related to article "Surgical management of BRCA-mutation carriers: A single institution experience"
<p>This record contains raw data related to article “Surgical management of BRCA-mutation carriers: A single institution experience"</p> <p>Abstract:</p> <p><strong>Introduction: </strong> The optimal surgical management of BRCA-mutation carriers remains a subject of debate. To evaluate the appropriateness of breast cancer (BC) treatment, the oncological outcomes of BRCA-mutation carriers treated either with breast-conserving therapy (BCT) or mastectomy were compared. Additionally, the role of bilateral salpingo-oophorectomy (BSO) and potential independent predictive factors for BC treatment were analyzed.</p> <p><strong>Materials and methods: </strong> We retrospectively reviewed all the consecutive patients with a pathogenic germline mutation in the BRCA1/2 genes tested at our Institution between July 2008 and October 2018. Primary end-points were disease-free survival (DFS), distant disease-free survival (DDFS), and overall survival (OS).</p> <p><strong>Results: </strong> The characteristics and outcomes of 124 BRCA-associated BC patients were analyzed. Overall, 69 (55.7%) and 55 (44.3%) patients underwent BCT and mastectomy, respectively; 72 (58.1%) patients underwent BSO. After a median interval of 13.3 months, 24 patients underwent mastectomy after primary BCT. There was no significant difference in terms of DFS, DDFS, and OS between patients treated with BCT or mastectomy (p = 0.39,p = 0.27,p = 0.265, respectively). Patients treated with BSO had significantly better DDFS and OS compared to ovarian conservation (p = 0.033,p = 0.040, respectively). Three independent predictive factors for BCT were identified: age ≤41 years, genetic testing performed post-operatively, and breast tumors ≤21 mm.</p> <p><strong>Conclusions: </strong> Our data suggest that BRCA-mutation carriers treated with BCT present similar oncological outcomes compared to mastectomy. Ovarian preservation decreases survival. Young BRCA-mutated patients with small BCs may not need up-front mastectomy, and BSO might be performed when ovarian cancer risk epidemiologically rises and potential reproductive desire is fulfilled.</p>
Dataset related to article: Distinct neural signatures of pulvinar in C9orf72 amyotrophic lateral sclerosis mutation carriers and noncarriers
<table> <tbody> <tr> <td> <p><span>The database includes clinical and MRI morphological data from a sample of 19 ALS patients carrying the C9orf72 mutation (ALSC9+), 19 non-mutation-carriers ALS patients (ALSC9-), and 19 ALS mimics (ALSmimics). The reported data consist of:<span> </span>demographic data (i.e., Age and Sex assigned at birth), clinical data (i.e., Bulbar/spinal onset, ALSFRS, Survival, disease duration, and King's Staging System scores), and volumetric information on the pulvinar subniclei (mm^3 and percentage of intracranial volume).</span></p> </td> </tr> </tbody> </table>
Dateset related to article "Spinocerebellar Ataxia Type 1: One‑Year Longitudinal Study to Identify Clinical and MRI Measures of Disease Progression in Patients and Presymptomatic Carriers "
<p>This dataset contains clinical information (neuropsychological evaluations, structural MRI measures, etc.) on patients with Spinocerebellar Ataxia included in the study reported at title</p>
Blood expression profiles of fragile X premutation carriers identify genes involved in neurodegenerative and infertility phenotypes
GEO Series GSE48903. Homo sapiens. 39 samples. Type: Expression profiling by array.
Mitochondrial carrier SLC25A19 is required for respiratory chain function
GEO Series GSE253270. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Mitochondrial carrier homolog 2 (MTCH2) is necessary for AML survival
GEO Series GSE147508. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mitochondrial dicarboxylate carrier SLC25A10 promotes HCC cell resistance to apoptosis by upregulating BCL2A1 expression [RNA-seq]
GEO Series GSE279929. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Aviation Safety Reporting System: Air Carrier (FAR 121) Flight Crew Fatigue Reports
A sampling of reports involving air carrier (FAR 121) flight crew fatigue.
NASA 3D Models: Orbital Replacement Unit Carrier
Polygons: 3794 Vertices: 2776
Loss of the mitochondrial pyruvate carrier promotes stem cell gene expression in colon adenomas.
GEO Series GSE136710. Mus musculus. 109 samples. Type: Other.
Carrier Subclass Year 4
GEO Series GSE281131. Homo sapiens. 156 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Mitochondrial dicarboxylate carrier SLC25A10 promotes HCC cell resistance to apoptosis by upregulating BCL2A1 expression [ChIP-seq]
GEO Series GSE279928. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Carrier Subclass
GEO Series GSE246010. Homo sapiens. 556 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Gene expression profiling of PBMC from normal individuals, chronic hepatitis B carriers and hepatocellular carcinoma patients
GEO Series GSE58208. Homo sapiens. 27 samples. Type: Expression profiling by array.
Expression profiling of the solute carrier gene family in the chicken intestine
GEO Series GSE8495. Gallus gallus. 28 samples. Type: Expression profiling by array.
caArray_strue-00134: Identification of BRCA1 mutation carriers using oligonucleotide arrays
GEO Series GSE91006. Homo sapiens. 83 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.