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5,794 results for “exposures”
The response of E. coli to exposure to the biocide polyhexamethylene biguanide
GEO Series GSE2827. Escherichia coli. 6 samples. Type: Expression profiling by array.
The miRNA microarray data after UVB exposure to human keratinocyte HaCaT cells
GEO Series GSE142534. synthetic construct; Homo sapiens. 2 samples. Type: Expression profiling by array.
Gene expression analysis of different motor neuron genotypes and their response to biological exposure and AAV treatment [neuropathology]
GEO Series GSE281714. Homo sapiens. 23 samples. Type: Other.
Ancestral gestational exposure to widely used neonicotinoid thiacloprid leads to global DNA methylation alterations in spermatozoa in three generations of male mice [MEDIP-seq]
GEO Series GSE234861. Mus musculus. 21 samples. Type: Methylation profiling by high throughput sequencing.
Bystander response to 2.5 Gy of protons in a human 3-dimensional skin model in 16 h after exposure
Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling. Thus identification and characterization of bystander mechanisms will help to development of new treatments of patients with a radiation exposure. In the present study we irradiated 3-dimensional tissue model of human epidermis Epi-200 (Mat-Tek Ashland MA) with 2.5 Gy protons. By exposing only a thin strip across the center of the EPI-200 tissue we have been able to measure global gene expression responses in directly irradiated and bystander cells located at 0.125-0.375 0.375-0.625 0.625-875 mm from the irradiation line. The data were analyzed using BRB-Array Tools (NIH) and further gene ontology analysis and network analysis was performed with Panther (Applied Biosystems) and IPA (Ingenuity) accordingly. Significantly responding genes were identified at all distances and included sets common to both direct and bystander responses. False discovery rate in bystander samples did not exceed 20% (p=0.001) and was sufficiently low in the samples obtained after the whole tissue exposure (0.06-1.16%). Analysis of the fragments cut at the same distance revealed 52 54 and 88 differentially expressed genes. These gene lists overlapped each other had from 3 to 12 genes in common including CLED2 S100A7A. Samples obtained after the whole tissue exposure discovered 949 differentially expressed genes. Moreover the performed gene ontology analysis showed there overrepresentation of TP53 pathway (pathways p=2.04E-02) a common marker of direct irradiation response and also overrepresentation of the following groups of genes: signal transduction (p=4.52E-04) cell communication (p=1.24E-04) and cell cycle in the category of biological processes; DNA helicase activity (p=2.54E-07) receptor binding (p=6.19E-04) calcium ion binding proteins (p=2.57E-03) as the molecular functions. Differentially expresses genes of bystander samples had few categories in common such as cell communication (p=2.36E-03) and signal transduction (p=2.42E-03) among the biological processes and receptor activity (p=4.54E-03) among the molecular functions. Categories specific for the bystander samples included G-protein coupled receptors (p=7.24E-03) and ligand-gated ion channels (p=4.16E-03) suggesting a role of external stimulation and ion trafficking in bystander mechanisms. Radiation induced gene expression in 3-dimensional tissue model Epi-200 was measured in 16 hours after exposure to 2.5 Gy of protons. Four independent experiments were performed for the samples collected at different distances from the irradiation line (125-375 375-625 and 625-875 micrometers) using three tissue fragments per a data point. Moreover three sets of whole tissue irradited samples were also generated for 0 and 2.5 Gy (6 samples total) and used for comparison of bystander and direct responses.
Identifying radiation exposure biomarkers from mouse blood transcriptome
Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological samples here. Mice were exposed to ionizing radiation (Cesium-138 source) and whole blood was collected by cardiac puncture 6 hours post treatment. Doses were 0 (7 samples) 2 (5 samples) and 8 (6 samples) gy.
XMM-Newton Large-Scale Structure Deep Full-Exposure X-Ray Source Catalog
This table contains some of the X-ray results from the final release of the multiwavelength XMM-Large Scale Structure (LSS) data set, covering the full survey area of 11.1 deg<sup>2</sup>. The 124 XMM-Newton observations used in the complete XMM-LSS are described in Section 2 and Table 1 of the primary reference paper (Chiappetti et al. 2013, hereafter Paper II). The X-ray data were processed with the latest XMM-LSS XAMIN pipeline version. The catalogs in Paper II supersede the catalog from the first paper in this series (Paper I: Pierre et al. 2007, MNRAS, 382, 279, available at the HEASARC as the XMMLSS table) pertaining to the initial 5 deg<sup>2</sup>. The authors provide X-ray source lists in the customary soft and hard energy bands (0.5-2 keV and 2-10 keV, respectively) for a total of 6721 objects in the deep full-exposure 2XLSSd catalog presented in this table, and 5572 objects in the catalog limited to 10 ks exposures (available at the HEASARC as the XMMLSS10KS table), above a detection likelihood of 15 in at least one band. At the XMMLSS web site which they maintain (<a href="http://cosmosdb.iasf-milano.inaf.it/XMM-LSS/">http://cosmosdb.iasf-milano.inaf.it/XMM-LSS/</a>), the authors also provide a multiwavelength catalog, cross-correlating their list of X-ray sources with infrared, near-infrared, optical and ultraviolet catalogs. Customary data products, such as X-ray FITS images and thumbnail images from the Canada-France-Hawaii Telescope Legacy Survey and the Spitzer Wide-Area Infrared Extragalactic Survey, are made available there, together with their data base in Milan, which can be queried interactively. In this table, the authors provide the source list for the full area (11.1 square degrees) of the XMM-LSS, with a total of 6721 point-like or extended sources above a detection likelihood of 15 in either the 0.5-2 or 2-10 keV bands. This table, the 2XLSSd "deep catalog" version containing the result of the analysis of the full-length exposures, lists the main X-ray parameters, while further multiwavelength parameters and data products (X-ray images and optical/IR thumbnails) are available at the Milan XMM-LSS database site referenced above. It supersedes the first XMM-LSS version (Pierre et al. 2007, available at the HEASARC as the XMMLSS table). Analogously to Paper I, only sources with an off-axis angle < 13 arcmin were processed by the authors' X-ray data processing pipeline software, XAMIN. The catalog includes all the extended sources classified in the customary C1 and C2 classes (see Section 3.6 of Paper II) plus all point-like sources with a point source detection likelihood (DET_LH) greater than 15 (so-called non-spurious sources). This table was created by the HEASARC in February 2013 based on the <a href="https://cdsarc.cds.unistra.fr/ftp/cats/J/MNRAS/429/1652">CDS catalog J/MNRAS/429/1652</a> file 2xlssd.dat. This is a service provided by NASA HEASARC .
WISE All-Sky Single Exposure (L1b) Source Table
NASA's Wide-field Infrared Survey Explorer (WISE; Wright et al. 2010) mapped the sky at 3.4, 4.6, 12, and 22 μm (W1, W2, W3, W4) in 2010 with an angular resolution of 6.1", 6.4", 6.5", & 12.0" in the four bands. WISE achieved 5σ point source sensitivities better than 0.08, 0.11, 1 and 6 mJy in unconfused regions on the ecliptic in the four bands. Sensitivity improves toward the ecliptic poles due to denser coverage and lower zodiacal background.The All-Sky Release includes all data taken during the WISE full cryogenic mission phase, 7 January 2010 to 6 August 2010, that were processed with improved calibrations and reduction algorithms. Release data products include an Atlas of 18,240 match-filtered, calibrated and coadded image sets, a Source Catalog containing positional and photometric information for over 563 million objects detected on the WISE images, and an Explanatory Supplement that is a guide to the format, content, characteristics and cautionary notes for the WISE All-Sky Release products.The WISE All-Sky Data Release Single-exposure Source Working Database contains positions and brightness information, uncertainties, time of observation and assorted quality flags for 9,479,433,101 "sources" detected on the individual WISE 7.7s (W1 and W2) and 8.8s (W3 and W4) Single-exposure images. Because WISE scanned every point on the sky multiple times, the Single-exposure Database contains multiple, independent measurements of objects on the sky.Entries in the Single-exposure Source Table include detections of real astrophysical objects, as well as spurious detections of low SNR noise excursions, transient events such as hot pixels, charged particle strikes and satellite streaks, and image artifacts light from bright sources including the moon. Many of the unreliable detections are flagged in the Single-exposure Table, but they have not been filtered out as they were for the Source Catalog. Therefore, the Table must be used with caution. Users are strongly encouraged to read the Cautionary Notes before using the Table.
Effects of low dose space radiation exposures on the splenic metabolome
Future space missions will include return to the Moon and long duration deep space roundtrip missions to Mars. Leaving the protection that Low Earth Orbit provides will unavoidably expose astronauts to higher cumulative doses of space radiation, in addition to other stressors, e.g. microgravity. Immune regulation is known to be impacted and it remains to be seen whether prolonged effects will be encountered in deep space that can have an adverse impact on health. In this study we investigated the effects in overall metabolism of three different low dose radiation exposures (γ-rays, 16O, and 56Fe) in spleen from male C57BL/6 mice at 1, 2, and 4 months after exposure. Forty metabolites were identified with significant enrichment in purine metabolism, tricarboxylic acid cycle, fatty acids, acylcarnitines, and amino acids. Early perturbations were more prominent in the γ irradiated samples, while longer term responses shifted towards the high energy particle effects. Regression analysis showed a positive correlation of fatty acids with time and negative association with γ-rays, while degradation of purines were positively associated with time. Taken together, there is a strong suggestion of mitochondrial implication and the possibility of long term effects in DNA repair and nucleotide pools following radiation exposure.
WISE All-Sky Single Exposure (L1b) Frame Metadata Table
NASA's Wide-field Infrared Survey Explorer (WISE; Wright et al. 2010) mapped the sky at 3.4, 4.6, 12, and 22 μm (W1, W2, W3, W4) in 2010 with an angular resolution of 6.1", 6.4", 6.5", & 12.0" in the four bands. WISE achieved 5σ point source sensitivities better than 0.08, 0.11, 1 and 6 mJy in unconfused regions on the ecliptic in the four bands. Sensitivity improves toward the ecliptic poles due to denser coverage and lower zodiacal background.The All-Sky Release includes all data taken during the WISE full cryogenic mission phase, 7 January 2010 to 6 August 2010, that were processed with improved calibrations and reduction algorithms. Release data products include an Atlas of 18,240 match-filtered, calibrated and coadded image sets, a Source Catalog containing positional and photometric information for over 563 million objects detected on the WISE images, and an Explanatory Supplement that is a guide to the format, content, characteristics and cautionary notes for the WISE All-Sky Release products.The WISE All-Sky Data Release Single-exposure Source Working Database contains positions and brightness information, uncertainties, time of observation and assorted quality flags for 9,479,433,101 "sources" detected on the individual WISE 7.7s (W1 and W2) and 8.8s (W3 and W4) Single-exposure images. Because WISE scanned every point on the sky multiple times, the Single-exposure Database contains multiple, independent measurements of objects on the sky.Entries in the Single-exposure Source Table include detections of real astrophysical objects, as well as spurious detections of low SNR noise excursions, transient events such as hot pixels, charged particle strikes and satellite streaks, and image artifacts light from bright sources including the moon. Many of the unreliable detections are flagged in the Single-exposure Table, but they have not been filtered out as they were for the Source Catalog. Therefore, the Table must be used with caution. Users are strongly encouraged to read the Cautionary Notes before using the Table.
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [iron]
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) iron (56Fe) particles 1, 3, 7, 14 and 28 days after exposure. Unsupervised clustering analysis of gene expression segregated samples according to the radiation (IR) response, and time after exposure with 56Fe-IR showing the greatest level of gene modulation. 1H-IR exposures showed little differential transcript modulation. Network analysis categorized the major differentially expressed genes into cell cycle, oxidative responses and transcriptional regulation functional groups. Transcriptional networks identified key nodes regulating expression. Individual transcription factors were inferred to be active at 1, 3, 7, 14 and 28 days after exposure. Validation of the signal transduction network by protein analysis showed that particle IR clearly regulates a long lived signaling mechanism for p38 MAPK signaling and NFATc4 activation. Electrophoresis mobility shift assays supported the role of additional key transcription factors GATA-4, STAT-3 and NF-kB as regulators of the response at specific time points. These data suggest that the molecular response to 56Fe-IR is unique and shows long-lasting gene expression in cardiomyocytes, up to 28 days after exposure. Additionally, proteins involved in signal transduction and transcriptional activation via DNA binding play a role in the response to high charge (Z) and energy (E) particles (HZE). Our study may have implications for NASA's efforts to develop heart disease risk estimates for astronauts safety via identification of specific HZE-IR molecular markers and for patients receiving conventional and particle radiotherapy. Transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) iron (56Fe) particles 1, 3, 7, 14 and 28 days after exposure.
Transcriptome Profiles in Normal Human Bronchial Epithelial Cells after Exposure to gamma-rays and different HZE particles
Distinct transcriptome profiles in response to low-LET and high-LET and different radiation qualities of HZE particles. Total RNA obtained from HBEC3KT cells after 1 4 12 and 24 hours of radiation. Mock-irradiated samples at each time point and control samples before radiation (0 hour) were also collected.
WISE 3-Band Cryo Single Exposure (L1b) Frame Metadata Table
The WISE 3-Band Cryo Data Release products are comprised of data taken during the mission's 3-Band Cryo survey phase. This phase covers the time following the exhaustion of solid hydrogen in the WISE payload outer cryogen tank, while the detectors and telescope were still cooled by the inner cryogen tank. During this time, WISE's W1, W2 and W3 bands were operational and continued to acquire useful data, but the W4 detector was saturated by thermal emission from the warming telescope. The sensitivity achieved in the W1 and W2 bands was similar to that during the full cryogenic mission phase. The W3 measurement sensitivity was degraded and decreased steadily during the 3-Band Cryo phase because of the increasing telescope temperature and decreasing exposure times. WISE scanned approximately 30% of the sky during the 3-Band Cryo survey phase continuing with the same strategy that was used during the full cryogenic survey. The following table contains brief descriptions of all metadata information that is relevant to the processing of Single-exposure (level 1) images and the extraction of sources from the corresponding Single-exposure images. The table contains the unique scan ID for a specific scan frame and the reconstructed right ascension and declination of the level 1b frame center. Much of the information in this table is processing-specific, and may not be of interest to general users (e.g. flags indicating whether frames have been processed or not, and the date and time for starting of the pipeline, etc.). The metadata table also contains some characterization and derived statistics of the Single-expsoure image frames, basic photometric parameters used for photometry and derived statistics for extracted sources and artifacts. For example, it contains median pixel values of the coadded sky coverage map, the number of sources with profile-fit photometry Signal-to-Noise (SNR) greater than 3, and the total number of real sources affected by artifacts such as electronic ghosts, etc.
Simulated Galactic Cosmic Ray Exposure Activates Dose-Dependent DNA Repair Response and Downregulates Glucosinolate Pathway in Arabidopsis Seedlings
This study's objective was to develop an understanding of the biological effects of space radiation on plants with the goal of producing fresh food during long duration space missions to support astronauts' nutritional and psychological needs.10-day-old Arabidopsis seedlings were exposed to simulated Galactic Cosmic Rays (GCR) and assessed for transcriptomic changes. The simulated GCR irradiation was carried out in the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Lab (BNL). The exposures were conducted acutely for two dose points at 40 cGy or 80 cGy, with sequential delivery of proton, helium, oxygen, silicon, and iron ions. Control and irradiated seedlings were then harvested and stabilized in RNAlater at 3 hrs. post irradiation. Total RNA was isolated for transcriptomic analyses using RNAseq. The data revealed that the transcriptomic responses were dose-dependent, with significant upregulation of DNA repair pathways and downregulation of glucosinolate biosynthetic pathways. Glucosinolates are important for plant pathogen defense and for the taste of a plant, which are both relevant to growing plants for spaceflight. These findings fill in knowledge gaps of how plants respond to radiation in beyond-Earth environments.
Long-read sequencing reveals increased occurrence of genomic variants and adenosine methylation in Bacillus pumilus SAFR-032 after long-duration flight exposure onboard the International Space Station
Bacillus pumilus SAFR-032, an endospore-forming bacterial strain, was investigated to determine its methylation pattern (methylome) change, compared to ground control, after direct exposure to space conditions onboard the International Space Station (ISS) for 1.5 years. The resulting ISS-flown and non-flown strains were sequenced using the Nanopore MinION and an in-house method and pipeline to identify methylated positions in the genome. Our analysis indicated genomic variants and m6A methylation increased in the ISS-flown SAFR-032. To complement the broader omics investigation and explore phenotypic changes, ISS-flown and non-flown strains were compared in a series of laboratory-based chamber experiments using an X-ray irradiation source (doses applied at 250, 500, 750, 1000 and 1250 Gy); results show a potentially higher survival fraction of ISS-flown DS2 at the two highest exposures. Taken together, results from this study document lasting changes to the genome by methylation, potentially triggered by conditions in spaceflight, with functional consequences for the resistance of bacteria to stressors expected on long-duration missions beyond low Earth orbit.
XMM-Newton Large-Scale Structure Uniform 10-ksec Exposure X-Ray Source Catalog
This table contains some of the X-ray results from the final release of the multiwavelength XMM-Large Scale Structure (LSS) data set, covering the full survey area of 11.1 deg<sup>2</sup>. The 124 XMM-Newton observations used in the complete XMM-LSS are described in Section 2 and Table 1 of the primary reference paper (Chiappetti et al. 2013, hereafter Paper II). The X-ray data were processed with the latest XMM-LSS XAMIN pipeline version. The catalogs in Paper II supersede the catalog from the first paper in this series (Paper I: Pierre et al. 2007, MNRAS, 382, 279, available at the HEASARC as the XMMLSS table) pertaining to the initial 5 deg<sup>2</sup>. The authors provide X-ray source lists in the customary soft and hard energy bands (0.5-2 keV and 2-10 keV, respectively) for a total of 5572 objects in the catalog limited to 10 ks exposures presented in this table, and a total of 6721 objects in the deep full-exposure 2XLSSd catalog (available at the HEASARC as the XMMLSSDEEP table), above a detection likelihood of 15 in at least one band. At the XMMLSS web site which they maintain (<a href="http://cosmosdb.iasf-milano.inaf.it/XMM-LSS/">http://cosmosdb.iasf-milano.inaf.it/XMM-LSS/</a>), the authors also provide a multiwavelength catalog, cross-correlating their list of X-ray sources with infrared, near-infrared, optical and ultraviolet catalogs. Customary data products, such as X-ray FITS images and thumbnail images from the Canada-France-Hawaii Telescope Legacy Survey and the Spitzer Wide-Area Infrared Extragalactic Survey, are made available there, together with their data base in Milan, which can be queried interactively. In this table, the authors provide the source list for the full area (11.1 square degrees) of the XMM-LSS, with a total of 5572 point-like or extended sources above a detection likelihood of 15 in either the 0.5-2 or 2-10 keV bands. This table, the "standard" 2XLSS catalog containing the results of the analysis of the survey area using uniform 10-ksec exposures for all pointings longer than 10 ksec, lists the main X-ray parameters, while further multiwavelength parameters and data products (X-ray images and optical/IR thumbnails) are available at the Milan XMM-LSS database site referenced above. It supersedes the first XMM-LSS version (Pierre et al. 2007, available at the HEASARC as the XMMLSS table). Analogously to Paper I, only sources with an off-axis angle < 13 arcmin were processed by the authors' X-ray data processing pipeline software, XAMIN. The catalog includes all the extended sources classified in the customary C1 and C2 classes (see Section 3.6 of Paper II) plus all point-like sources with a point source detection likelihood (DET_LH) greater than 15 (so-called non-spurious sources). This table was created by the HEASARC in February 2013 based on the <a href="https://cdsarc.cds.unistra.fr/ftp/cats/J/MNRAS/429/1652">CDS catalog J/MNRAS/429/1652</a> file 2xlss.dat. This is a service provided by NASA HEASARC .
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [proton]
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) proton (56Fe) particles 1, 3, 7, 14 and 28 days after exposure. Unsupervised clustering analysis of gene expression segregated samples according to the radiation (IR) response, and time after exposure with 56Fe-IR showing the greatest level of gene modulation. 1H-IR exposures showed little differential transcript modulation. Network analysis categorized the major differentially expressed genes into cell cycle, oxidative responses and transcriptional regulation functional groups. Transcriptional networks identified key nodes regulating expression. Individual transcription factors were inferred to be active at 1, 3, 7, 14 and 28 days after exposure. Validation of the signal transduction network by protein analysis showed that particle IR clearly regulates a long lived signaling mechanism for p38 MAPK signaling and NFATc4 activation. Electrophoresis mobility shift assays supported the role of additional key transcription factors GATA-4, STAT-3 and NF-kB as regulators of the response at specific time points. These data suggest that the molecular response to 56Fe-IR is unique and shows long-lasting gene expression in cardiomyocytes, up to 28 days after exposure. Additionally, proteins involved in signal transduction and transcriptional activation via DNA binding play a role in the response to high charge (Z) and energy (E) particles (HZE). Our study may have implications for NASA's efforts to develop heart disease risk estimates for astronauts safety via identification of specific HZE-IR molecular markers and for patients receiving conventional and particle radiotherapy. Transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) proton (56Fe) particles 1, 3, 7, 14 and 28 days after exposure.
NEOWISE 2-Band Post-Cryo Single Exposure (L1b) Known Solar System Object Possible Association List
The NEOWISE Post-Cryo Data Release products were generated using data taken during the mission's Post-Cryo survey phase. This phase covers the time following the exhaustion of solid hydrogen in the WISE payload inner cryogen tank, when the detectors and optics gradually warmed until they reached a stable equilibrium temperature near 73.5 K. During this time, WISE's W1 and W2 detectors continued to acquire high quality imaging data with sensitivities close to that during the mission's cryogenic survey phases. The W3 and W4 detectors were fully saturated by the thermal emission from the warming telescope. WISE scanned approximately 70% of the sky during the Post-Cryo survey phase continuing with the same strategy that was used during the full cryogenic survey. The Known Solar System Object Possible Associations List is a compendium of asteroids and comets, with orbits known at the time of WISE second-pass data processing, that were predicted to be within the field-of-view at the time of individual WISE exposures. Individual objects were observed multiple times, so may have multiple entries in the list. When the predicted position of a solar system object is in proximity to a detection in the WISE single-exposures, the WISE source position and brightness information are also provided.
Subaru Prime Focus Camera (Suprime-Cam) Exposures Log
This table contains the Subaru Prime Focus Camera (Suprime-Cam) log of exposures having observation type = 'OBJECT' (those with 'BIAS', 'FLAT' and other types are not included) which have been made since April 2001. Note that from the version of Nov. 2005 on, the number of rows has significantly increased because those data with worse position determination (up to 30 arcsec error) are now included. The data currently extend to November 2005 and it is anticipated that they will be regularly updated Suprime-Cam is an 80-mega pixels (10240 x 8192) mosaic CCD camera, for the wide-field prime focus of the 8.2m Subaru telescope. Suprime-Cam covers a field of view 34' x 27', a unique facility among the 8-10m class telescopes, with a resolution of 0.202 arcseconds per pixel. The focal plane consists of ten high-resistivity 2kx2k CCDs developed by MIT Lincoln Laboratory, which are cooled by a large Stirling-cycle cooler. The CCD readout electronics was designed to be scalable, which allows the multiple read-out of tens of CCDs. It takes 50 seconds to readout entire arrays. A filter-exchange mechanism of the jukebox type is designed that can hold up to ten large filters (205 x 170 x 15 mm<sup>3</sup>). The wide-field corrector is basically a three-lens Wynne-type, but has a new type of atmospheric dispersion corrector. The corrector provides a flat focal plane and an un-vignetted field of view of 30' in diameter. The achieved co-planarity of the focal array mosaic is smaller than 30 um peak-to-peak, which realizes mostly the seeing limited image over the entire field. The median seeing in the I_c-band, measured over one year and a half, is 0.61 arcseconds. The PSF anisotropy in Suprime-Cam images, estimated by stellar ellipticities, is about 2% under this median seeing condition. At the time of its commissioning, Suprime-Cam had the largest survey speed, which is defined as the field of view multiplied by the primary mirror area of the telescope, among those cameras built for sub-arcsecond imaging. For more details, see: Miyazaki et al., Publ. Astron. Soc. Japan 54, 833-853, 2002 (2002PASJ...54..833M). This table was created by the HEASARC in September 2007 based on CDS table B/subaru/suprimc.dat (the ReadMe file for the latter was tagged with a date of August 25th, 2007). This is a service provided by NASA HEASARC .
Mouse fecal microbiome after exposure to high LET radiation
Space travel is associated with continuous low-dose-rate exposure to high Linear Energy Transfer (LET) radiation. Pathophysiological manifestations after low-dose radiation exposure are strongly influenced by non-cytocidal radiation effects including microbiome and cellular gene expression. Using a mouse model for exposure to high LET radiation we observed substantial changes in the composition and functional potential of the microbiome. These were paralleled by changes in the abundance of multiple metabolites which were related to the enzymatic activity of the altered metagenome by means of metabolic network modeling. There was a complex dynamic in microbial and metabolic composition at different radiation doses suggestive of transient dose-dependent interactions between microbial ecology and signals from the host s cellular damage repair processes. Functional shifts included features associated with dysbiosis at the onset of chronic inflammatory responses which could prMouse fecal microbiome after exposure to high LET radiatione-dispose space travelers to systemic long-term health risks.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.