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1,847 results for “Psoriasis”
Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects
ClinicalTrials.gov study NCT05172726. IPD Sharing: NO. Countries: 2. Publications: 0.
supplementary materials of NMN supplement ameliorates psoriasis-associated inflammation, oxidative stress and mitochondrial dysfunction by activating SIRT1 pathway
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Figure 7 from: Almudaris SA, Gatea FK (2024) Effects of topical Ivermectin on imiquimod-induced Psoriasis in mouse model – Novel findings. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e114753
Figure 7 Histopathological section of mice skin (clobetasol control group) showing hyperkeratosis (black arrow), absence of parakeratosis & Munro's abscess. And epidermal granular layer (yellow arrow) with mild acanthosis, mild papillary thinning, and few rete ridges (green arrow). The dermis shows mild lymphocytic infiltrate. H&E stain (4×,10×).
Figure 11 from: Almudaris SA, Gatea FK (2024) Effects of topical Ivermectin on imiquimod-induced Psoriasis in mouse model – Novel findings. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e114753
Figure 11 Comparison between induced non-treated group and all induced treated groups regarding histopathological scores (Baker score) and observational score (PASI score).
Figure 4 from: Almudaris SA, Gatea FK (2024) Effects of topical Ivermectin on imiquimod-induced Psoriasis in mouse model – Novel findings. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e114753
Figure 4 Histopathological section of mice skin (healthy control group) showing normal skin architecture including K = keratin, E = epidermis, D = dermis, AD = adnexa, S.C = subcutaneous tissue, M = muscles, B.V = blood vessels. H&E stain (4×,10×).
Figure 3 from: Almudaris SA, Gatea FK (2024) Effects of topical Ivermectin on imiquimod-induced Psoriasis in mouse model – Novel findings. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e114753
Figure 3 Scoring for skin inflammation severity, the pictures show different inflammation levels of the dorsal skin on which the test substances were applied on day 8 of the Experiment. A. Represents the healthy group; B. Represents the IMQ-induced group; C. Represents the vehicle group; D. Represents Clobetasol treated group; E. Represents the Ivermectin treated group; F. Represents Ivermectin + Clobetasol treated group.
Figure 6 from: Almudaris SA, Gatea FK (2024) Effects of topical Ivermectin on imiquimod-induced Psoriasis in mouse model – Novel findings. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e114753
Figure 6 Histopathological section of mice skin (vehicle group) showing hyperkeratosis, parakeratosis (black arrow), with focal neutrophilic infiltration (the Munro's abscess) in red arrow, with epidermal acanthosis and thinning papillae and elongated rete ridges (green arrow), and lack of granular layer. The dermis shows moderate to severe inflammatory lymphocytic infiltration (blue arrow). H&E stain (4×,10×).
Figure 9 from: Almudaris SA, Gatea FK (2024) Effects of topical Ivermectin on imiquimod-induced Psoriasis in mouse model – Novel findings. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e114753
Figure 9 Histopathological section of mice skin (Ivermectin treatment group) showing mild keratosis (black arrow), with the absence of Munro's abscess and parakeratosis and epidermal mild acanthosis with few rete ridges and mild papillary thinning (green arrow). The dermis shows severe lymphocytic infiltrate. H&E stain (4×,10×).
Figure 2 from: Almudaris SA, Gatea FK (2024) Effects of topical Ivermectin on imiquimod-induced Psoriasis in mouse model – Novel findings. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e114753
Figure 2 Induction of Psoriasis in mice. A Mouse before Induction. B Mouse after Induction by Imiquimod cream.
Figure 8 from: Almudaris SA, Gatea FK (2024) Effects of topical Ivermectin on imiquimod-induced Psoriasis in mouse model – Novel findings. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e114753
Figure 8 Histopathological section of mice skin (Ivermectin treatment group) showing mild keratosis (black arrow), with the absence of Munro's abscess and parakeratosis and epidermal mild acanthosis with few rete ridges and mild papillary thinning (green arrow). The dermis shows severe lymphocytic infiltrate. H&E stain (4×,10×, 40×).
Figure 10 from: Almudaris SA, Gatea FK (2024) Effects of topical Ivermectin on imiquimod-induced Psoriasis in mouse model – Novel findings. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e114753
Figure 10 Comparison between induced non-treated group and all induced treated groups regarding tissue biomarkers (IL-10, IL-17, TNF-a, and VEGF).
Figure 5 from: Almudaris SA, Gatea FK (2024) Effects of topical Ivermectin on imiquimod-induced Psoriasis in mouse model – Novel findings. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e114753
Figure 5 Histopathological section of mice skin (induction group) showing hyperkeratosis, parakeratosis (black arrow), with multifocal dense neutrophilic infiltration (the Munro's abscess) in red arrow, with epidermal acanthosis and thinning papillae and rete ridges appearance (green arrow), and lack of granular layer. The dermis shows moderate to severe inflammatory lymphocytic infiltration (blue arrow). H&E stain (4×,10×, 40×).
Effect of Topical Amlodipine on Imiquimod-Induced Psoriasis in Mice
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Cross-sectional Evaluation of Biological Markers of Cardiovascular Disease in Children and Adolescents With Psoriasis
ClinicalTrials.gov study NCT01122095. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Turmeric Based Therapy in the Treatment of Psoriasis: A Clinical Trial
ClinicalTrials.gov study NCT04071106. IPD Sharing: YES. Countries: 0. Publications: 5.
Long Term Safety and Efficacy Study of Calcitriol 3 mcg/g Ointment in Pediatric Subjects With Plaque Psoriasis
ClinicalTrials.gov study NCT02125279. IPD Sharing: NO. Countries: 5. Publications: 0.
A Plaque Test Study With LEO 35299 in Psoriasis Vulgaris
ClinicalTrials.gov study NCT01580488. IPD Sharing: NO. Countries: 1. Publications: 0.
A 12-Day Randomized, Blinded, Vehicle and Active Comparator-Controlled Study to Determine the Efficacy and Safety of Six Concentrations of Topical E6201 Gel in Subjects With Psoriasis Vulgaris
ClinicalTrials.gov study NCT01268527. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety and Efficacy Study of Adalimumab in the Treatment of Plaque Psoriasis
ClinicalTrials.gov study NCT01646073. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety and Efficacy of IDP-122 in the Treatment of Participants With Plaque Psoriasis
ClinicalTrials.gov study NCT02515097. IPD Sharing: YES. Countries: 1. Publications: 0.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.