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10,356
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Dataset results
10,356 results for “Severity”
TGF-β3 increases the severity of radiation-induced oral mucositis and salivary gland fibrosis in a mouse model
<p>This is a collection of results from a preclinical trial investigating the effects of TGF-B3 treatment on healthy tissue radiotoxicity in C57BL/6 mice after fractionated head and neck radiotherapy. Survival, body weight, oral mucositis, lip dermatitis, saliva volume, and salivary gland collagen deposition were monitored. This data set is used in the manuscript "TGF-β3 increases the severity of radiation-induced oral mucositis and salivary gland fibrosis in a mouse model". </p> <p> </p>
Data on: Projecting spatiotemporal dynamics of severe fever with thrombocytopenia syndrome in the mainland of China
<p>This dataset is the data used in the paper of Global change biology entitled "<span>Projecting spatiotemporal dynamics of severe fever with thrombocytopenia syndrome in the mainland of China</span>". <span>We use an integrated multi-model, multi-scenario framework to assess the impact of global climate change on SFTS disease in the mainland of China. The SFTS incidence in three time periods (2030-2039, 2050-2059, 2080-2089) is predicted to be increased as compared to the 2010s in the context of various RCPs. The projected spatiotemporal dynamics of SFTS will be heterogeneous across provinces. Notably, we predict possible outbreaks in Xinjiang and Yunnan in the future, where only sporadic cases have been reported previously. </span><span>These findings highlight the need for population awareness of SFTS in endemic regions, and enhanced monitoring in potential risk areas. </span></p>
Prediction of Port Recovery Time after a Severe Storm Project
<p>Predicting the impact of incoming tropical cyclones on ports in terms of the number of days underperforming is crucial for the effective management of the ports. However, existing methods perform undesirably due to the limited data and the inherent uncertainty associated with cyclone trajectory forecasting. This study applies a recommendation algorithm to address these challenges by focusing on predicting port impact rankings instead of predicting the duration of port impacts, which is often inaccurate and unreliable. First, we have collected comprehensive features of ports and hurricanes in the Gulf of Mexican and employed a modular time-series regression model to determine the duration of port impacts due to tropical cyclones, leveraging vessel count data extracted from the Automatic Identification System (AIS). Inspired by the recommendation algorithm, we recast tropical cyclones and ports as “user” and “items,” respectively, while the duration of port impacts represents their “interaction,” offering an innovative approach to model and analyze cyclone effects on ports. The Factorization Machine (FM) is adopted to learn the relationship between features (i.e., ports and cyclones) and subsequently conduct the port impact ranking. Finally, utilizing the hurricanes Alex, Ian, and Nicole that happened in 2022 as testing cases, the FM-based model excels in prediction performance and robustness against uncertainties compared to the widely used distance-based method. This study aims to provide port authorities and other stakeholders with a trustworthy tool for informed disaster management decisions, thereby enhancing port resilience. </p>
Methotrexate for Severe Vulvar Lichen Sclerosus
ClinicalTrials.gov study NCT07352917. IPD Sharing: UNDECIDED. Countries: 1. Publications: 12.
Lung Volume Reduction for Severe Emphysema by Stereotactic Ablative Radiation Therapy
ClinicalTrials.gov study NCT03673176. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Pandemic Triage Score in Patients With Known or Suspected Severe Acute Respiratory Syndrome (SARS) CoronaVirus (CoV) 2 Infection
ClinicalTrials.gov study NCT04371471. IPD Sharing: YES. Countries: 1. Publications: 7.
Clinical Investigation Into Inhaled Treprostinil Sodium in Patients With Severe Pulmonary Arterial Hypertension (PAH)
ClinicalTrials.gov study NCT00147199. IPD Sharing: Not stated. Countries: 10. Publications: 1.
A Multicentre, Open Label Phase IIIb/IV Study of Subcutaneously Administered Raptiva in the Treatment of Adult Subjects With Moderate to Severe Plaque Psoriasis
ClinicalTrials.gov study NCT00287118. IPD Sharing: Not stated. Countries: 1. Publications: 1.
AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department
ClinicalTrials.gov study NCT04669288. IPD Sharing: NO. Countries: 1. Publications: 0.
An Investigational Study to Evaluate Experimental Medication BMS-986165 in Japanese Participants With Moderate-to-Severe Psoriasis
ClinicalTrials.gov study NCT03924427. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Evaluation of Efficacy and Safety of Symbicort® as an add-on Treatment to Spiriva® in Patients With Severe COPD.
ClinicalTrials.gov study NCT00496470. IPD Sharing: Not stated. Countries: 9. Publications: 4.
The Efficacy of Cobitolimod in Patients With Moderate to Severe Active Ulcerative Colitis
ClinicalTrials.gov study NCT03178669. IPD Sharing: NO. Countries: 10. Publications: 1.
Safety and Efficacy Study of JNJ-64304500 in Participants With Moderately to Severely Active Crohn's Disease
ClinicalTrials.gov study NCT02877134. IPD Sharing: Not stated. Countries: 14. Publications: 2.
Safety of Single and Repeat Treatments of DaxibotulinumtoxinA for Injection for Treatment of Moderate to Severe Glabellar Lines
ClinicalTrials.gov study NCT03004248. IPD Sharing: NO. Countries: 2. Publications: 2.
Study of Dupilumab Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis
ClinicalTrials.gov study NCT01859988. IPD Sharing: Not stated. Countries: 7. Publications: 6.
Etrasimod Dose-Ranging Versus Placebo as Induction Therapy Study in Adult Japanese Subjects With Moderately to Severely Active Ulcerative Colitis
ClinicalTrials.gov study NCT05061446. IPD Sharing: YES. Countries: 1. Publications: 1.
Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis.
ClinicalTrials.gov study NCT04250337. IPD Sharing: YES. Countries: 4. Publications: 1.
A Study Comparing the Efficacy and Safety of Etrolizumab to Infliximab in Participants With Moderate to Severe Ulcerative Colitis Who Are Naïve to Tumor Necrosis Factor (TNF) Inhibitors
ClinicalTrials.gov study NCT02136069. IPD Sharing: YES. Countries: 20. Publications: 2.
Efficacy and Safety of a Retinoid in the Treatment of Severe Chronic Hand Eczema
ClinicalTrials.gov study NCT00817063. IPD Sharing: YES. Countries: 1. Publications: 4.
A Study of RoActemra/Actemra (Tocilizumab) Given Subcutaneously in Combination With Traditional DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis
ClinicalTrials.gov study NCT01232569. IPD Sharing: Not stated. Countries: 22. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.