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2,326 results for “clusters”
Raw Diffraction Images: Formation of a highly dense tetra rhenium cluster in a protein crystal and its implications in medical imaging.
<p>Exploration of a “time on shelf” protein structure containing the radiopharmaceutical synthon <em>fac</em>-[Re(CO)<sub>3</sub>(H<sub>2</sub>O)<sub>3</sub>]<sup>+ </sup>as an <em>in vivo</em> reaction vessel to form tetranuclear rhenium clusters appropriate for theranostic applications.That a protein crystal can serve as a chemical reaction vessel is intrinsically fascinating. That it can produce an electron dense tetranuclear rhenium cluster compound from a rhenium tricarbonyl tribromo starting compound adds to the fascination. The cluster has been synthesised before in vitro when it formed under basic conditions. Therefore its synthesis in a protein crystal grown at pH4.5 is even more unexpected. The X-ray crystal structures presented here are for the protein hen egg white lysozyme incubated with the rhenium tricarbonyl tribromo compound for periods of 1 year and 2 years. These reveal a completed, very well resolved, tetra rhenium cluster after two years and an intermediate state after 1 year where the carbonyl ligands to the rhenium cluster are not yet clearly resolved. A dense tetra-nuclear rhenium cluster, and its technetium form, offers enhanced medical imaging contrast. The raw diffraction images for the one year and two year protein structure, described in the manuscript, is made avaliable on the Zenodo repository.</p>
IMPROVE AKI Cluster-Randomized Trial
ClinicalTrials.gov study NCT03556293. IPD Sharing: YES. Countries: 1. Publications: 2.
Prevention and Acute Treatment of Chronic Cluster Headache Compared to Standard of Care
ClinicalTrials.gov study NCT01701245. IPD Sharing: NO. Countries: 4. Publications: 1.
Study to Evaluate the Long-term Safety and Tolerability of USL261 in Patients With Seizure Clusters
ClinicalTrials.gov study NCT01529034. IPD Sharing: NO. Countries: 10. Publications: 2.
MIDAS Cluster Randomized Controlled Trial of Implementation Strategies to Optimize Use of Medications in VA Clinical Settings
ClinicalTrials.gov study NCT05065502. IPD Sharing: YES. Countries: 1. Publications: 2.
Community Based Interventions to Improve HIV Outcomes in Youth: a Cluster Randomised Trial in Zimbabwe
ClinicalTrials.gov study NCT03719521. IPD Sharing: YES. Countries: 1. Publications: 15.
A Prospective Cluster-Randomized, Controlled Crossover Trial to Validate an Electronic "Resistance Calculator"
ClinicalTrials.gov study NCT05304221. IPD Sharing: NO. Countries: 1. Publications: 10.
Somatic Acupressure for Symptom Cluster Management in Breast Cancer Survivors
ClinicalTrials.gov study NCT06412107. IPD Sharing: NO. Countries: 1. Publications: 1.
Non-invasive Neurostimulation of the Vagus Nerve for the Treatment of Cluster Headache
ClinicalTrials.gov study NCT01792817. IPD Sharing: NO. Countries: 1. Publications: 2.
Cluster-randomized Controlled Trial of Mindfulness-Based Cognitive Therapy Effects on Anxiety and Stress
ClinicalTrials.gov study NCT06019299. IPD Sharing: YES. Countries: 1. Publications: 1.
Mobile Food Market Cluster Randomized Trial
ClinicalTrials.gov study NCT05672186. IPD Sharing: YES. Countries: 1. Publications: 1.
A Study of Galcanezumab in Participants With Chronic Cluster Headache
ClinicalTrials.gov study NCT02438826. IPD Sharing: YES. Countries: 12. Publications: 2.
Self-Help Plus to Enhance Early Development: A Cluster-Randomized Controlled Trial of Maternal Mental Health, Child Cognitive Abilities, and Socio-Behavioral Skills Among South Sudanese Refugee Mother
ClinicalTrials.gov study NCT07062341. IPD Sharing: NO. Countries: 1. Publications: 1.
A Randomized Multicentre Study for the Acute Relief of Episodic and Chronic Cluster Headache.
ClinicalTrials.gov study NCT01958125. IPD Sharing: NO. Countries: 4. Publications: 1.
A Cluster-randomized Trial to Assess a Sexual Assault Prevention Intervention in Adolescents in Nairobi, Kenya
ClinicalTrials.gov study NCT02771132. IPD Sharing: NO. Countries: 1. Publications: 2.
Cluster Randomized Trial of Hospitals to Assess Impact of Targeted Versus Universal Strategies to Reduce Methicillin-resistant Staphylococcus Aureus (MRSA) in Intensive Care Units (ICUs)
ClinicalTrials.gov study NCT00980980. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Cluster of Differentiation Antigen 19/22(CD19/22) CAR T Cells (AUTO3) for the Treatment of Diffuse Large B Cell Lymphoma
ClinicalTrials.gov study NCT03287817. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Family Connections Cluster RCT in Zambia
ClinicalTrials.gov study NCT05358795. IPD Sharing: YES. Countries: 1. Publications: 1.
Decreasing Stunting by Reducing Maternal Depression in Uganda: A Cluster Randomized Controlled Trial (CRCT) for Improved Nutrition Outcomes
ClinicalTrials.gov study NCT03573713. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
A 1-year Trial to Inform About Long-term Exposure to Eptinezumab in Participants With Chronic Cluster Headache (cCH)
ClinicalTrials.gov study NCT05064397. IPD Sharing: Not stated. Countries: 9. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.