Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
537
datasets available to search
ShareScore release 0.9.0
Dataset results
537 results for “genome structure”
Consticted migration is associated with stable 3D genome structure differences in cancer cells (RNA-Seq)
GEO Series GSE143677. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Role of Top1 and Genome structure in SARS-CoV-2 infection [RNA-Seq human]
GEO Series GSE162615. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
3D structure of the genome of F. graminearum strain PH-1
GEO Series GSE243436. Fusarium graminearum. 2 samples. Type: Other.
Distinct leukemogenic mechanism of acute promyelocytic leukemia based on genomic structure of PML-RARα fusion gene
GEO Series GSE207432. Homo sapiens. 8 samples. Type: Expression profiling by array.
Reprogramming of 3D genome structure underlying HSPC development in zebrafish [HiC]
GEO Series GSE262187. Danio rerio. 9 samples. Type: Other.
Genome-wide structure changes during neuronal differentiation drive gene regulatory networks
GEO Series GSE156671. Homo sapiens. 95 samples. Type: Expression profiling by high throughput sequencing; Other.
Structurally Complex Osteosarcoma Genomes Exhibit Limited Heterogeneity within Individual Tumors and across Evolutionary Time
A key characteristic of osteosarcoma is extensive and complex genomic rearrangements. However, published models explaining how these genomic rearrangements occur disagree about if these rearrangements occur early in tumor progression and then are stable afterwards, or if there is ongoing genomic instability. Previous studies have employed bulk sequencing technologies to characterize genomic alterations. A limitation of this approach is that it averages all changes within the bulk sample, essentially masking intra-sample heterogeneity and making evaluation of ongoing genomic instability difficult. To overcome this limitation and compliment previous work, we utilized single-cell whole genome sequencing to quantify somatic copy number alterations (SCNA). By interrogating individual cells within a sample, we were able to examine intra-sample heterogeneity. We found that the SCNA patterns between cells within a single sample were remarkably consistent, which supports the concept that the genomes of osteosarcoma tumors are relatively stable after early genome fragmentation events.
Genome-wide mapping of chromatin structure remodeling RSC1 during growth mycelia in the Magnaporthe oryzae [ChIP-seq + Mnase-seq]
GEO Series GSE284398. Pyricularia oryzae. 33 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide Investigation of Population Structure in Myanmar
GEO Series GSE74100. Homo sapiens. 240 samples. Type: SNP genotyping by SNP array.
Chromatin immunoprecipitation for genome-wide mapping of endogenous G-quadruplex DNA structures
GEO Series GSE99205. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The Role of BAZ2-dependent Chromatin Remodeling in Suppressing G4 DNA Structures and Associated Genomic Instability [INDUCE-seq]
GEO Series GSE291629. Homo sapiens. 18 samples. Type: Other.
Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer
GEO Series GSE148079. Homo sapiens. 51 samples. Type: Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing.
3D genomics analysis identifies enhancer hijacking caused by structural alterations and extrachromosomal circular DNA formation [HiChIP]
GEO Series GSE228246. Homo sapiens. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Structural and Genome-wide Analysis Support a Role for SETMAR in Transcriptional Regulation
GEO Series GSE103076. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
3D genomics analysis identifies enhancer hijacking caused by structural alterations and extrachromosomal circular DNA formation [ChIP-Seq]
GEO Series GSE228166. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The Role of BAZ2-dependent Chromatin Remodeling in Suppressing G4 DNA Structures and Associated Genomic Instability [G4]
GEO Series GSE285882. Homo sapiens. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Consticted migration is associated with stable 3D genome structure differences in cancer cells
GEO Series GSE143678. Homo sapiens. 43 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
3D genomic analysis reveals novel enhancer-hijacking caused by complex structural alterations that drive oncogene overexpression
GEO Series GSE228247. Homo sapiens. 34 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The multiscale distribution of radiation-induced DNA damage and its impact on local genome structure
GEO Series GSE306338. Homo sapiens. 16 samples. Type: Other.
Structural genomic variation among soybean NIL's using CGH approach
GEO Series GSE31072. Glycine max. 7 samples. Type: Genome variation profiling by genome tiling array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.