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937 results for “Tobacco”
Figure 7 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 7 Forest plot tail defect.
Figure 6 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 6 Forest plot neck defect.
Figure 3 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 3 Forest plot teratozoospermia.
Figure 9 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 9 Forest plot FSH.
Figure 5 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 5 Forest plot head defect.
Figure 12 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 12 Forest plot concentration.
Figure 2 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 2 Forest plot oligozoospermia.
Figure 11 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 11 Forest plot volume.
Figure 1 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 1 Literature search flow diagram.
Figure 8 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 8 Forest plot testosterone.
Figure 13 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 13 Forest plot sperm DNA fragmentation.
Figure 4 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 4 Forest plot asthenozoospermia.
Figure 10 from: Ramon R, Warli SM, Rasyid N, Atmoko W (2024) Effect of tobacco smoking and alcohol consumption on semen quality and hormone reproductive levels in infertile males: A systematic review and meta analysis. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e113854
Figure 10 Forest plot LH.
How New Zealand adults who smoked understand novel tobacco 'endgame' policies. Qualitative analysis using the Associative Propositional Evaluation model to determine comprehension. Raw data.
<p>Raw data used for analysis presented in results paper. </p> <p><strong><span>Compliance with Ethical Standards</span></strong></p> <p><span>Ethics approval was sought from the Health and Disability Ethics Committee (HDEC), but the study was deemed out of HDEC’s scope as it was an observational study that would not involve more than minimal risk, that is, no more risk than participants might encounter during everyday life.</span></p> <p><strong><span>Disclosure statement</span></strong></p> <p><span>This study was funded with a grant [COE1-009] from the Foundation for a Smoke-Free World, Inc. (“FSFW”), a US nonprofit 501(c)(3) private foundation. The FSFW’s mission is to end smoking in this generation. Through September 2023, the Foundation received charitable gifts from PMI Global Services Inc. (“PMI”). Independent from PMI since its founding in 2017, the Foundation continues to operate in a manner that ensures its independence from any commercial entity. This study is, under the terms of the grant agreement with FSFW, editorially independent of FSFW. The FSFW were not involved in the conception, design, conduct, data collection, analysis and interpretation of data; nor did the FSFW review or have any involvement in the writing of the paper or involvement or restrictions regarding publication. The contents, selection, and presentation of facts, as well as any opinions expressed herein, are the sole responsibility of the authors and under no circumstances should they be regarded as reflecting the positions of FSFW. </span><span>None of the authors nor does the Centre have any commercial interests in any smoking cessation programs or aids or nicotine or tobacco products.</span></p>
[DATABASE] Comparing the Effectiveness, Tolerability, and Acceptability of Heated Tobacco Products and Refillable Electronic Cigarettes for Cigarette Substitution (CEASEFIRE): Randomized Controlled Trial
<p><strong>Background: </strong>People who smoke and who face challenges trying to quit or wish to continue to smoke may benefit by switching from traditional cigarettes to noncombustible nicotine delivery alternatives, such as heated tobacco products (HTPs) and electronic cigarettes (ECs). HTPs and ECs are being increasingly used to quit smoking, but there are limited data about their effectiveness.</p> <p><strong>Objective: </strong>We conducted the first randomized controlled trial comparing quit rates between HTPs and ECs among people who smoke and do not intend to quit.</p> <p><strong>Methods: </strong>We conducted a 12-week randomized noninferiority switching trial to compare effectiveness, tolerability, and product satisfaction between HTPs (IQOS 2.4 Plus) and refillable ECs (JustFog Q16) among people who do not intend to quit. The cessation intervention included motivational counseling. The primary endpoint of the study was the carbon monoxide-confirmed continuous abstinence rate from week 4 to week 12 (CAR weeks 4-12). The secondary endpoints included the continuous self-reported ≥50% reduction in cigarette consumption rate (continuous reduction rate) from week 4 to week 12 (CRR weeks 4-12) and 7-day point prevalence of smoking abstinence.</p> <p><strong>Results: </strong>A total of 211 participants completed the study. High quit rates (CAR weeks 4-12) of 39.1% (43/110) and 30.8% (33/107) were observed for IQOS-HTP and JustFog-EC, respectively. The between-group difference for the CAR weeks 4-12 was not significant (P=.20). The CRR weeks 4-12 values for IQOS-HTP and JustFog-EC were 46.4% (51/110) and 39.3% (42/107), respectively, and the between-group difference was not significant (P=.24). At week 12, the 7-day point prevalence of smoking abstinence values for IQOS-HTP and JustFog-EC were 54.5% (60/110) and 41.1% (44/107), respectively. The most frequent adverse events were cough and reduced physical fitness. Both study products elicited a moderately pleasant user experience, and the between-group difference was not significant. A clinically relevant improvement in exercise tolerance was observed after switching to the combustion-free products under investigation. Risk perception for conventional cigarettes was consistently higher than that for the combustion-free study products under investigation.</p> <p><strong>Conclusions: </strong>Switching to HTPs elicited a marked reduction in cigarette consumption among people who smoke and do not intend to quit, which was comparable to refillable ECs. User experience and risk perception were similar between the HTPs and ECs under investigation. HTPs may be a useful addition to the arsenal of reduced-risk alternatives for tobacco cigarettes and may contribute to smoking cessation. However, longer follow-up studies are required to confirm significant and prolonged abstinence from smoking and to determine whether our results can be generalized outside smoking cessation services offering high levels of support.</p>
Varied effects of tobacco smoke and e-cigarette vapor suggest that nicotine does not affect endothelium-dependent relaxation and nitric oxide signaling
<p>Chronic smoking causes dysfunction of vascular endothelial cells, evident as a reduction of flow-mediated dilation in smokers, but the role of nicotine is still controversial. Given the increasing use of e-cigarettes and other nicotine products, it appears essential to clarify this issue. We studied extracts from cigarette smoke (CSE) and vapor from e-cigarettes (EVE) and heated tobacco (HTE) for their effects on vascular relaxation, endothelial nitric oxide signaling, and the activity of soluble guanylyl cyclase. The average nicotine concentrations of CSE, EVE, and HTE were 164, 800, and 85 µM, respectively. At a dilution of 1:3, CSE almost entirely inhibited the relaxation of rat aortas and porcine coronary arteries to acetylcholine and bradykinin, respectively, while undiluted EVE, with a 15-fold higher nicotine concentration, had no significant effect. With about 50% inhibition at 1:2 dilution, the effect of HTE was between CSE and EVE. Neither extract affected endothelium-independent relaxation to an NO donor. At the dilutions tested, CSE was not toxic to cultured endothelial cells but, in contrast to EVE, impaired NO signaling and inhibited NO stimulation of soluble guanylyl cyclase. Our results demonstrate that nicotine does not mediate the impaired endothelium-dependent vascular relaxation caused by smoking.</p>
Sniff Tobacco Bottle
"***...It is insane when thinking about how much gramms of this snuff tobacco we took on the mine floor."*** - This is a quote of a former Dutch miner. As this quote indicates, seeing a miner sniffing some snuff tobacco was a common scene within the mines. Moreover, snuff tobacco was especially handy, since usual cigarettes were striclty forbidden within the mines, due to explosion danger. Therefore, these smoke-free tobacco products, which were sniffed as a pulver from the back of the hand, were quite popular among miners. The name of the brand is printed on the bottle: **Pöschl Schmalzer**. What is behind this name? The German brand Pöschl Tabak GmbH was founded in 1902 and is worldwide the largest snuff tobacco company. Its products, bottles and equipments are quite often in German and Dutch mining museums to be found, due to their uniqueness and their historical value. Last but not least, it has to be mentioned that Schmalzer is a Bavarian speciality which is originally made of brasil tobaccos. Source: Objaverse 1.0 / Sketchfab
Healing of Apical periodontitis-the Effect of Diabetes Mellitus and Tobacco Smoking
ClinicalTrials.gov study NCT04812171. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
In-vivo Extraction of Lead, Cadmium and Tobacco Specific Nitrosamines From Swedish 'Snus' in Regular Snus Users
ClinicalTrials.gov study NCT01838473. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Integrating Tobacco Use Cessation Into HIV Care and Treatment in Kisumu County, Kenya
ClinicalTrials.gov study NCT05351606. IPD Sharing: NO. Countries: 1. Publications: 0.
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