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Fig. 2 in Molecular screening for rickettsial bacteria and piroplasms in ixodid ticks surveyed from white-tailed deer (Odocoileus virginianus) and nilgai antelope (Boselaphus tragocamelus) in southern Texas
Fig. 2. Anocenter nitens, the tropical horse tick, infesting a white-tailed deer. As in horses, A. nitens ticks preferentially infest the ears of this cervid host. Photo Credit: Emma Mitchell
Fig. 14. Sakar Mts, N in Hard ticks (Acari: Ixodida) in Sakar Mountains, SE Bulgaria
Fig. 14. Sakar Mts, N of Yerusalimovo Village, 08.v.2024. Habitat of Hyalomma aegyptium.
Fig. 13 in Hard ticks (Acari: Ixodida) in Sakar Mountains, SE Bulgaria
Fig. 13. Sakar Mts, SE of Kolarovo Village, 11.v.2024. Habitat of Rhipicephalus turanicus.
Fig. 9 in Hard ticks (Acari: Ixodida) in Sakar Mountains, SE Bulgaria
Fig. 9. Sakar Mts, NE of Izvorovo Village, 08.v.2024. Habitat of Rhipicephalus turanicus.
Fig. 4. Sakar Mts, S in Hard ticks (Acari: Ixodida) in Sakar Mountains, SE Bulgaria
Fig. 4. Sakar Mts, S of Ustrem Village, 05.v.2021. Habitat of Haemaphysalis parva.
Data from: Systems biology of tissue-specific response to Anaplasma phagocytophilum reveals differentiated apoptosis in the tick vector Ixodes scapularis
Anaplasma phagocytophilum is an emerging pathogen that causes human granulocytic anaplasmosis. Infection with this zoonotic pathogen affects cell function in both vertebrate host and the tick vector, Ixodes scapularis. Global tissue-specific response and apoptosis signaling pathways were characterized in I. scapularis nymphs and adult female midguts and salivary glands infected with A. phagocytophilum using a systems biology approach combining transcriptomics and proteomics. Apoptosis was selected for pathway-focused analysis due to its role in bacterial infection of tick cells. The results showed tissue-specific differences in tick response to infection and revealed differentiated regulation of apoptosis pathways. The impact of bacterial infection was more pronounced in tick nymphs and midguts than in salivary glands, probably reflecting bacterial developmental cycle. All apoptosis pathways described in other organisms were identified in I. scapularis, except for the absence of the Perforin ortholog. Functional characterization using RNA interference showed that Porin knockdown significantly increases tick colonization by A. phagocytophilum. Infection with A. phagocytophilum produced complex tissue-specific alterations in transcript and protein levels. In tick nymphs, the results suggested a possible effect of bacterial infection on the inhibition of tick immune response. In tick midguts, the results suggested that A. phagocytophilum infection inhibited cell apoptosis to facilitate and establish infection through up-regulation of the JAK/STAT pathway. Bacterial infection inhibited the intrinsic apoptosis pathway in tick salivary glands by down-regulating Porin expression that resulted in the inhibition of Cytochrome c release as the anti-apoptotic mechanism to facilitate bacterial infection. However, tick salivary glands may promote apoptosis to limit bacterial infection through induction of the extrinsic apoptosis pathway. These dynamic changes in response to A. phagocytophilum in I. scapularis tissue-specific transcriptome and proteome demonstrated the complexity of the tick response to infection and will contribute to characterize gene regulation in ticks.
Data from: "Transcriptome sequence identity between Lyme disease tick vectors, Ixodes scapularis and Ixodes ricinus" in Genomic Resources Notes accepted 1 April 2014 to 31 May 2014
Ixodes scapularis and I. ricinus transmit the Lyme disease agent Borrelia burgdorferi in the U.S. and Europe, respectively. The only tick genome sequence available is that of I. scapularis, which constitutes a limitation for tick research. Recent evidences suggest that I. ricinus and I. scapularis transcriptomes share some degree of sequence identity. However, only the global transcriptome comparison reported here demonstrated that I. ricinus and I. scapularis share a 99.232±0.005 percent sequence identity with a very low frequency of INDELs. However, due to limitations of the current I. scapularis genome assembly, the number of aligned reads was only 26-27%. These results support the use of I. scapularis genome sequence as a reference for the analysis of I. ricinus transcriptomics and proteomics data, but addressing the limitations associated with the I. scapularis genome assembly.
FIGURE 61 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 61. Ixodes tasmani (common marsupial tick),, female, dorsal.
FIGURE 56 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 56. Ixodes holocyclus (paralysis tick), male, dorsal.
FIGURE 55 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 55. Ixodes holocyclus (paralysis tick), female, ventral.
FIGURE 20 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 20. Argas persicus (poultry tick), female, ventral.
FIGURE 62 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 62. Ixodes tasmani (common marsupial tick), female, ventral.
FIGURE 65 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 65. Rhipicephalus australis (Australia cattle tick), female, dorsal and ventral.
FIGURE 29 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 29. Amblyomma triguttatum (ornate kangaroo tick), female, ventral.
FIGURE 52 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 52. Ixodes hirsti (Hirst's marsupial tick), male, dorsal.
FIGURE 51 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 51. Ixodes hirsti (Hirst's marsupial tick), female, ventral.
FIGURE 53 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 53. Ixodes hirsti (Hirst's marsupial tick), male, ventral.
FIGURE 48 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 48. Ixodes cornuatus (southern paralysis tick), male, ventral.
FIGURE 47 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 47. Ixodes cornuatus (southern paralysis tick), male, dorsal.
FIGURE 57 in Ticks of Australia. The species that infest domestic animals and humans
FIGURE 57. Ixodes holocyclus (paralysis tick), male, ventral.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.