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ShareScore release 0.7.1
Dataset results
560 results for “Direct effects”
The Effect of Transcranial Direct Current Stimulation and Speech Language Therapy to Improve Language Functioning in Arabic Speakers With Aphasia Post-Stroke
ClinicalTrials.gov study NCT04644718. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Effects of Transcranial Direct Current Stimulation in Refractory Chronic Migraine and Medication-overuse Headache
ClinicalTrials.gov study NCT01752439. IPD Sharing: Not stated. Countries: 0. Publications: 0.
The dual pathway inhibitor rigosertib is effective in direct-patient tumor xenografts of head and neck squamous cell carcinomas
GEO Series GSE47864. Homo sapiens. 16 samples. Type: Expression profiling by array.
Eosinophils exert direct and indirect anti-tumorigenic effects in the development of esophageal squamous cell carcinoma
GEO Series GSE233668. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing.
An ultra effective method of generating extra multipotent cells from human fibroblasts via ultrasound-directed instant chromatin remodeling
GEO Series GSE86646. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Effect of BMP signaling levels on foregut specification during directed differentiation of BU3 NGPT human induced pluripotent stem cells
GEO Series GSE274939. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
An ultra effective method of generating extra multipotent cells from human fibroblasts via ultrasound-directed instant chromatin remodeling [MBD-seq]
GEO Series GSE86647. Homo sapiens. 4 samples. Type: Methylation profiling by high throughput sequencing.
Effect of site directed mutagenesis on transcriptomic difference between A549 (T/T) and A549 (C/C) cells
GEO Series GSE225330. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Effect of dietary supplementation with direct fed microbials (DFM) in chicken
GEO Series GSE41934. Gallus gallus. 2 samples. Type: Expression profiling by array.
Stretching inhibits tumor growth in MMTV-PYMT via a direct mechanical effect
GEO Series GSE316800. Mus musculus. 1 samples. Type: Other.
Direct comparison of effects of slow-freezing and vitrification procedures on rabbit late blastocyst transcriptome
GEO Series GSE50979. Oryctolagus cuniculus. 3 samples. Type: Expression profiling by array.
RELMα establishes a permissive environment for influenza infection through direct effects on lung epithelial cells
GEO Series GSE268747. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Direct effects of octreotide on osteoblast cell proliferation and function"
<p>This record contains data related to article" Direct effects of octreotide on osteoblast cell proliferation and function<strong>".</strong></p> <p> </p> <p><em>Purpose.</em> Octreotide (OCT) is a first-generation somatostatin analog (SSA) used in the treatment of acromegaly and neuroendocrine tumors (NETs). In both diseases, OCT interacts with somatostatin receptors 2 and 5 (SSTR2 and SSTR5), inhibiting hormone hypersecretion and cell proliferation. Skeletal health is an important clinical concern with acromegaly and NETs since acromegalic osteopathy and NET bone metastasis occur in a remarkable number of patients. While OCT’s effect on NET cells has been extensively investigated, its direct action on bone cells remains unknown.</p> <p><em>Methods.</em> Here we investigated OCT direct effects on cell proliferation, differentiation, mineralization, and chemoattractant capacity of murine primary osteoblasts and osteoblast cell line MC3T3-E1.</p> <p><em>Results.</em> OCT inhibited osteoblasts and MC3T3-E1 cell proliferation (-30% ± 16%, and -22 ± 4%, both p<0.05) and increased MC3T3-E1 cell apoptosis (+76 ± 32%, p<0.05 vs control).</p> <p>The anti-proliferative action of OCT was mediated by SSTR2 and SSTR5 in MC3T3-E1, while its proapoptotic effect was abrogated in SSTR2-silenced cells. The analysis of genes related to the early and late phases of osteoblast differentiation showed that OCT did not affect <em>Alp, Runx2</em>, <em>Bglap, Spp1, and Sost </em>levels in MC3T3-E1 cells. Similarly, OCT had no effect on ALP activity and mineralization in osteoblasts. In addition, <em>Vegfa</em> expression decreased in OCT-treated MC3T3-E1 cells and OCT inhibited pancreatic NET cell migration towards osteoblast-conditioned medium.</p> <p><em>Conclusion.</em>This study provides the first evidence of the direct action of OCT on osteoblasts which may have clinically relevant implications for the management of skeletal health in subjects with acromegaly and metastatic NETs.</p>
Effect of site directed mutagenesis on transcriptomic difference between H460 (T/T) and H460 (C/C) cells
GEO Series GSE213199. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
p53 regulates the conserved zebrafish microRNA-34 gene family, of which miR-34a has direct and p53-mediated effects including tumour suppression
GEO Series GSE205755. Danio rerio. 14 samples. Type: Expression profiling by high throughput sequencing.
Direct effects of IFNα on human CD8 T cells_without any other concomitant signals
GEO Series GSE17299. Homo sapiens. 3 samples. Type: Expression profiling by array.
Data set from the article Prinzivalli M, Sammarco G, Rampoldi B, Costa E, Corsi Romanelli MM. Comparison between specific and nonspecific assay in the evaluation of the anticoagulant effect of the Direct Oral Anticoagulants: Our experience in a cardiovascular hospital. Eur J Intern Med. 2019;60:e20‐e22. doi:10.1016/j.ejim.2018.10.005
<p>Data set from the article Prinzivalli M, Sammarco G, Rampoldi B, Costa E, Corsi Romanelli MM. Comparison between specific and nonspecific assay in the evaluation of the anticoagulant effect of the Direct Oral Anticoagulants: Our experience in a cardiovascular hospital. <em>Eur J Intern Med</em>. 2019;60:e20‐e22. doi:10.1016/j.ejim.2018.10.005</p>
Impact of Varying Lidar Measurement and Data Processing Techniques in evaluating Cirrus Cloud and Aerosol Direct Radiative Effects
<p>Range corrected signal of the two cirrus clouds, biomass burning and dust layers, used in the analysis carried out in the paper </p>
Effects of a novel neuromuscular training intervention on jump, sprint and change of direction in adult female soccer players
<p><span>Neuromuscular training is a training methodology used in sports to improve the physical performance of athletes. Soccer has physical demands of power and speed, so players need to develop sprinting, changing direction and jumping skills. According to these objectives, a novel neuromuscular training protocol is developed to improve physical performance in the variables of jumping, speed and change of direction in adult female soccer players. A protocol was based on mobility exercises, stability, anterior chain strength, lumbo-pelvic control, posterior chain strength and change of direction ability. Thirty-four female soccer players were randomly divided into control group (CG, n=17) and experimental group (EG, n=17) during 10 weeks of intervention. Experimental group improved bilateral and unilateral jumping ability (p=0.05; ES= 0.83 to 1.35), peak speed (p=0.05; ES=0.96) and 180COD in the intergroup analysis (p=0.05; ES=-1.29 to -1.39). Novel variables such as bilateral deficit and change of direction deficit showed significant improvements in the experimental group (p=0.05). In conclusion, the novel neuromuscular training program which included weekly progressions, unilateral and bilateral exercises, showed significant improvements in the physical performance of adult female soccer players.</span></p>
The linker histone H1.2 directs the genome-wide chromatin-association and facilitates the biological effects of the retinoblastoma tumour suppressor protein
GEO Series GSE98728. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.