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29,897 results for “activism”
Dataset for "Intra-intestinal analysis of the functional activity of microbiomes and its application to the common marmoset intestine"
<p>Dataset:</p> <p>data1_ExpressionProfile.xlsx: gene expression profile</p> <p>data2_AnnotationProfile.xlsx: gene annotation profile</p>
Intra-intestinal analysis of the functional activity of microbiomes and its application to the common marmoset intestine
<p>Supplementary Table Captions:</p> <p>Table S7. Assignment of genes to unknown gene clusters</p> <p>Table S8. AUC used to determine parameters for covariation analysis by benchmarking</p> <p>Table S9. Linked unknown gene clusters</p> <p>Table S10. Information on common marmosets</p> <p>Table S11. Dual index sequences</p> <p>Table S12. Sequencing statistics</p> <p>Table S13. RIN score of total RNA samples</p> <p>Table S14. Top 20 bacterial species in taxonomic profiling</p> <p>Table S15. Number of genes covered by the nonchimaeric genome in each parameter at the assembly step</p> <p>Table S16. Number of genes covered by the nonchimaeric genome in each parameter at the merge step</p> <p>Table S17. Distance between intestinal sites</p>
Data collected for: The contrasted impacts of grasshoppers on soil microbial activities in function of ecosystem productivity and herbivore diet
<p>Herbivory can have contrasted impacts on soil microbes and nutrient cycling, which has stimulated the development of conceptual frameworks exploring the links between below- and aboveground processes. The "productivity model" predicts that herbivores stimulate microbial activities and accelerate nutrient mineralization in productive ecosystems, while they have an opposite effect in less productive ecosystems. In parallel, the "diet model" predicts that herbivores feeding on conservative plants accelerate nutrient cycling while those feeding on exploitative plants decelerate nutrient cycling, due to changes in litter inputs. Since these two frameworks can lead to conflicting predictions in some cases, experimental evidence combining herbivore diet and productivity is required.</p> <p>During two consecutive years, we conducted an experiment controlling the presence of three grasshopper species consuming either grasses, forbs or both in twelve natural and managed alpine grasslands of contrasted productivities. In order to assess the effects of herbivory on soil microbes, we measured their enzymatic activities, their biomass and the soil potential nitrogen mineralization (PNM). Soil and vegetation characteristics were also determined in order to test if they modulated the effects of herbivory on microbes.</p> <p>Contrary to the predictions of the diet model, the effects of herbivory on microbial characteristics did not depend on the herbivores diet but relied on ecosystem productivity. The most productive sites were characterized by exploitative plant species which depleted N resources in the soil, and by microbes producing relatively few extracellular enzymes, leading to a lower PNM. Herbivory increased microbial biomass and decreased the production of extracellular enzymes in those sites, possibly through the stimulation of root exudates produced by exploitative species. The least productive sites were characterized by conservative plants, which led to the sequestration of soil C, and by microbes having a resource acquisition strategy (more extracellular enzymes, higher PNM). Herbivory decreased microbial biomass and increased the production of extracellular enzymes in those sites. This pattern can be explained by the loss of carbon associated with insect respiration, which increases the need for microbes to acquire resources and by a lower production of root exudates by conservative species. Therefore, the effects of two years of herbivory on soil microbes were at odds with the productivity model, which focuses instead on longer term effects corresponding to herbivory-induced changes in plant species composition. This highlights the multidimensional feature of the impacts of herbivory on ecosystem functioning, both in space and time.</p>
dataset for paper "Activation energy for pore opening in lipid membranes under an electric field"
<p>Dataset for the paper "Electropermeabilization of hydroperoxidized lipid membranes".</p> <p>Data was generated from Orbit Mini miniaturized bilayer workstation (Nanion Technologies, Munich, Germany), with an inserted microelectrode cavity array (MECA 4) recording chip (Ionera Technologies, Freiburg, Germany).</p> <p>The data files have format .abf, a standard format for electrophysiological data. <br> It can be read by applications such as for instance</p> <p>- Clampex and ClampFit, from the patch-clamp software suite pCLAMP, <br> - Elements Data Analyzer, associated with the elements data reader software from Elements-IC, </p> <p><br> or imported into Python through the package pyABF 2.3.5.</p> <p>import pyabf // abf=pyabf.ABF(path+"/"+f+"/"+abffile) // data = np.vstack((abf.sweepX, abf.data)) </p> <p>Data is organized in five folders named according to target hydroperoxidation degrees:<br> POPC<br> POPC-OOH 25%<br> POPC-OOH 50%<br> POPC-OOH 75%<br> POPC-OOH 100%</p> <p>Inside each of the five above files data is organized by date, and informed with the actual measured hydroperoxidation degree for a given sample. </p>
Supplementary files: A Comparative Study of Active Rock Glaciers Mapped from Geomorphic- and Kinematic-Based Approaches in Daxue Shan, Southeast Tibetan Plateau
<p>Supplement of "A Comparative Study of Active Rock Glaciers Mapped from Geomorphic- and Kinematic-Based Approaches in Daxue Shan, Southeast Tibetan Plateau". The supplementary files provide the outlines and parameters of the rock glaciers inventoried by InSAR-assist kinematic-based approach in the Daxue Shan, Southeast Tibet Plateau. </p> <p>Based on the Sentinel-1A ascending SAR images acquired between 2015 and 2019, we derived a five-year-long LOS mean velocity map of the study area. We then compiled a rock glacier inventory by synergistically interpreting the InSAR-derived surface displacements and geomorphic features based on Google Earth images.</p>
STORMS checklist: Dysbiosis of the enteric microbiota due to Crohn's disease treatment associated with MAIT cell activation
<p>STORMS checklist initiative to standardize reporting of human microbiome research, regarding submission to peer-reviewed journal.</p>
MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage
<p>Supplementary data and code of the article "MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage".</p>
Vibration and IMU Sensing Human Activity Dataset
<p>This dataset contains fine-grained human daily activity data collected by infrastructure vibration sensors and one on-wrist IMU sensor. This dataset is collected from six persons from two domestic homes, in total, there are 12 sub-datasets.</p> <p>For the naming, "p" means person and "l" means location.</p> <p>Each dataset has 11 columns, 1o of them stands for sensors' reading.</p> <p>* Due to the uploading platform, please<strong> <em>ignore</em> </strong>all files in the folder '__MACOSX', and files whose names start with '._'. These are computer system files, not parts of the shared dataset. </p> <p>** If you are going to use this dataset for any publications, we will appreciate you to cite this dataset properly.</p> <p>************************************************************</p> <p>The following content is copied from README.txt in the compressed folder:</p> <p>-----------------------<br> Labels:</p> <p>Keyboard typing 1<br> Using mouse 2<br> Handwriting 3<br> Cutting vegetables 4<br> Stir-frying vegetables 5<br> Wiping the table 6<br> Sweeping floor 7<br> Using vacuum to vacuum floor: 8<br> Open and close drawer: 9</p> <p>None Activity: 10</p> <p>-----------------------<br> 11 Columns:<br> 1: Activity label<br> 2: Vibration sensor put on the Living Area floor<br> 3: Vibration sensor put on the Living Area table<br> 4: Vibration sensor put on the Studying Area floor<br> 5: Vibration sensor put on the Studying Area desk<br> 6, 7, 8: Accelerometer X,Y,Z<br> 9, 10, 11: Gyroscope X,Y,Z</p> <p>-----------------------<br> All signals are zero-meaned.<br> The vibration sensors' sampling rate is roughly around 6500Hz, and the IMU sensors' original sampling rate is roughly around 235Hz.</p> <p>************************************************************</p> <p>New in Version 2:</p> <p>- Added extracted features from IMU data and vibration data for reference.</p> <p>- IMU signal is applied with a sliding window of 1.5 seconds with 0.75 seconds overlapping, then the feature is extracted in each window. The feature's description can be found here: https://dl.acm.org/doi/abs/10.1145/3410530.3414320</p> <p>- The vibration signal is applied with event detection to extract events in the vibration signal. For each event, we normalize it by its energy, then extract 10~490 Hz frequency amplitude as the feature.</p> <p> </p> <p>Disclaimer: Both event detection and feature extraction are empirical, we don't guarantee it is an optimal one.</p>
In vivo metallophilic self-assembly of a light-activated anticancer drug
<p>This data set contains all data of our submitted manuscript with the same title.</p> <p> </p>
No relationship between chronotype and timing of breeding when variation in daily activity patterns across the breeding season is taken into account
<p>There is increasing evidence that individuals are consistent in the timing of their daily activities, and that individual variation in temporal behaviour is related to the timing of reproduction. However, it remains unclear whether observed patterns relate to the timing of the onset of activity or whether an early onset of activity extends the time that is available for foraging. This may then again facilitate reproduction. Furthermore, the timing of activity onset and offset may vary across the breeding season, which may complicate studying the above mentioned relationships. Here, we examined in a wild population of great tits (Parus major) whether an early clutch initiation date may be related to an early onset of activity and/or to longer active daylengths. We also investigated how these parameters are affected by the date of measurement. In order to test these hypotheses we measured emergence and entry time from/into the nest box as proxies for activity onset and offset in females during the egg laying phase. We then determined active daylength. Both emergence time and active daylength were related to clutch initiation date. However, a more detailed analysis showed that the timing of activities with respect to sunrise and sunset varied throughout the breeding season both within and among individuals. The observed positive relationships are hence potentially statistical artifacts. After methodologically correcting for this date effect, by using data from the pre-egg laying phase, where all individuals were measured on the same days, neither of the relationships remained significant. Taking methodological pitfalls and temporal variation into account may hence be crucial for understanding the significance of chronotypes.</p>
COVID-19, physical activity, and health
<p>Dataset related to the project on COVID-19, physical activity, and health</p> <p>This dataset includes:</p> <p><strong>1) A codebook (including the name of the main variables)</strong></p> <p>--> "code_book_covid.xlsx"</p> <p><strong>2) The anonymous data set</strong></p>
Electronic appendix to: Spectral Induced Polarization (SIP) of Denitrification-Driven Microbial Activity in Column Experiments Packed with Calcareous Aquifer Sediments
<p>This is the electronic appendix of the publication <br> C. Strobel, S. Abramov, J. A. Huisman, O.A. Cirpka, A. Mellage (2022): Spectral Induced Polarization (SIP) of Denitrification-Driven Microbial Activity in Column Experiments Packed with Calcareous Aquifer Sediments (submitted)</p>
Data and code for Barrett, Martin, and Shepherd (2022) "Manipulation-specific cortical activity as mice handle food"
<p>This dataset contains the tracking data, spiking data, and ethograms necessary to reproduce the results of Barrett, Martin, and Shepherd (2022) "Manipulation-specific cortical activity as mice handle food". Also included is Matlab and R code that generates all of the figures, tables, and stats in the aforementioned paper.</p>
Antifungal activity of propolis extract against Candida albicans in patients with vulvovaginal candidiasis
<p>Abstract</p> <p><strong>Objective:</strong> To evaluate the antifungal activity of propolis extract against <em>Candida Albicans</em> (or <em>C. Albicans</em>) in patients with vulvovaginal candidiasis.</p> <p><strong>Method:</strong> The research presents a quantitative approach with an experimental design, with a population of <em>C. Albicans</em> strains isolated from patients diagnosed with vulvovaginal candidiasis who were admitted to the Gynecology Service of the Maria del Socorro Clinic, district of Ate - Lima, from which a sample of 34 strains was chosen in total, considering three repetitions per strain, obtaining 102 experimental units.</p> <p>The antifungal susceptibility test was carried out by the disc diffusion plate method using a single concentration of propolis extract, with fluconazole as a positive control.</p> <p><strong>Resultados:</strong> Propolis extract was shown to inhibit all strains of <em>C. albicans</em>, as was fluconazole, with the effect of the latter being significantly greater than that of the product under investigation.</p> <p><strong>Conclusion:</strong> The conclusion is that propolis extract does show antifungal activity against <em>C. albicans</em> in patients with vulvovaginal candidiasis.</p> <p><strong>Keywords:</strong> Propolis extract, <em>Candida Albicans</em>, Antifungal activity, Vulvovaginal candidiasis.</p> <p> </p>
Investigating the "two-hit hypothesis": effects of prenatal maternal immune activation and adolescent cannabis use on neurodevelopment in mice
<p>Prenatal exposure to maternal immune activation (MIA) and chronic adolescent cannabis use have both been identified as environmental risk factors for neuropsychiatric disorders. However, most individuals exposed to a single risk factor do not typically develop major mental illness, which suggests that multiple exposures may be required for illness onset. Here, we examine whether combined exposure to prenatal MIA and adolescent delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, lead to enduring neuroanatomical and behavioural changes in adult offspring, potentially reflecting changes in humans indicative of mental illness. </p> <p>Mice were prenatally exposed to a viral mimetic, poly I:C (5mg/kg), or vehicle at gestational day (GD)9, and then postnatally exposed to chronic THC (5mg/kg) or vehicle by intraperitoneal injections during adolescent development (postnatal day [PND]28-45). Longitudinal in vivo whole-brain magnetic resonance imaging (MRI) was performed pre-treatment, PND25, post-treatment, PND50, and in adulthood, PND85, followed by a series of behavioural tests aimed at assessing anxiety-like and locomotor, social, and sensorimotor gating behaviour. Post-mortem assessment of cannabinoid (CB)1 and 2 receptor expressing cells was performed in developmentally altered regions identified by MRI (anterior cingulate and somatosensory cortices, striatum, and hippocampus). We hypothesized that there would be differential, but synergistic effects of each exposure.</p> <p>Briefly, we found subtle deviations in neurodevelopmental trajectory and subthreshold anxiety-like behaviours were observed in mice exposed to both risk factors. Sex-dependent effects were observed in patterns of shared brain-behaviour covariation, suggesting that exposure to MIA and THC may affect males and females in different ways. Density of CB1 and CB2 receptor positive cells was significantly decreased in all regions assessed for all mice exposed to either one or both risk factors, relative to controls.</p> <p>These findings suggest that there may be a cumulative effect of risk factor exposure on gross neuroanatomical and behavioural development, and that the endocannabinoid system may be sensitive to both prenatal MIA, adolescent THC, or the combination. For full details, see our publication: .</p> <p>In this dataset, you will find a total of 243 preprocessed structural MRIs (in MINC format) acquired at postnatal day ~25, ~50, and ~85 in mice exposed to poly I:C or vehicle control (0.9% sterile saline) at GD9, and then postnatally treated with vehicle or THC from PND 28-45. These are T1-weighted structural images at 100 micron isotropic resolution acquired on a 7 Tesla Bruker Biospec 70/30; matrix size of 180 x 160 x 90; 14.5 minutes, 20 degrees and TE/TR of 4.5/20 ms (2 averages, ~14 minutes). Anesthesia was induced with 3% isoflurane in oxygen and a (0.075 mg/kg bolus) dexmedetomidine injection. Anesthesia was maintained during the scan between 1.5-0.5% isoflurane, and a constant infusion of dexmedetomidine (0.05mg/kg/h continuous mg/kg during scan). T1-weighted scans were preprocessed by stripping native coordinates, flipping left-right to maintain fidelity, denoising, correcting inhomogeneities in the bias field using the N4 algorithm, and registering in LSQ6 alignment (i.e. 6 degrees of freedom are allowed for imagine alignment: translations and rotations along x, y, and z dimensions). The demographics information for each animal is included in the demographics.csv file. </p> <p>Behavioural tests were performed following the postnatal day 85 scans in all animals with a 2 day rest period. These include: open field test, three chambered social approach, and prepulse inhibition. The data for all of these tests is presented in its own individual .csv spreadsheet.</p> <p>Included in this data set are the structural MRIs in MINC format, the behavioural .csv data, and a readme.txt file providing further detail on the data structure and content, and on how to interpret the data column titles. DICOMS are also available for the structural MRI data, as are the raw (not-preprocessed) MINC files, available upon request to the authors. </p> <p>Finally, the authors would like to acknowledge the funding bodies that supported the completion of this work including the Canadian Institute for Health Research, the Fonds de Recherche du Québec en Santé, and the Healthy Brains for Healthy Lives at McGill University.</p>
Supplementary Simulation Data for "Conformational Selection of a Tryptophan Side Chain Drives the Generalized Increase in Activity of PET Hydrolases Through a Ser/Ile Double Mutation"
<p>Additional simulation data for "Conformational Selection of a Tryptophan Side Chain Drives the Generalized Increase in Activity of PET Hydrolases Through a Ser/Ile Double Mutation", which has been submitted as a preprint to ChemRxiv.</p>
Text-fig. 6. Shallowing pattern during the Middle Miocene to Late Miocene/Pliocene due to increasing magmatic activity as an external parameter. a: palaeobathymetry map during the Middle Miocene to Pliocene; b: sea level change curve indicating a shallowing pattern; c: relative changes of sea level and magmatic activity curve (Haq et al. 1987, Soeria-Atmadja et al. 1998, Muljana 2012). in Lithofacies And Ichnofacies Of Turbidite Deposits, West Java, Indonesia
Text-fig. 6. Shallowing pattern during the Middle Miocene to Late Miocene/Pliocene due to increasing magmatic activity as an external parameter. a: palaeobathymetry map during the Middle Miocene to Pliocene; b: sea level change curve indicating a shallowing pattern; c: relative changes of sea level and magmatic activity curve (Haq et al. 1987, Soeria-Atmadja et al. 1998, Muljana 2012).
Figure 1 in Toxicity and ovicidal activity of different entomopathogenic fungi, Hirsutella extracts on Tetranychus urticae (Acari: Tetranychidae)
Figure 1. Accumulated mortality of T. urticae females at 24, 48 and 72 h after being fed with mulberry leaf discs treated with different concentrations of crude extract, six species of Hirsutella under residual effect bioassay. For each extract and mite, means followed by the same letter are not significantly different (p = 0.05; Tukey HDS test).
Text-fig. 1. a: Map of France showing geographic position of Saint-Bauzile (source: http://d-maps.com/m/europa/france/france/ france09.gif). b: Overview of the active diatomite quarry at the Montagne d'Andance, photograph taken in 2017. c: SEM image of a frustule of pennate diatom (cf. Navicula sp.) from Saint-Bauzile. d) SEM image of frustules forming a colony of centric diatoms (cf. Diatoma sp.) from Saint-Bauzile. in Evidence For Wildfires During Deposition Of The Late Miocene Diatomites Of The Konservat-Lagerstätte Lake Saint-Bauzile (Ardèche, France) - Preliminary Results
Text-fig. 1. a: Map of France showing geographic position of Saint-Bauzile (source: http://d-maps.com/m/europa/france/france/ france09.gif). b: Overview of the active diatomite quarry at the Montagne d'Andance, photograph taken in 2017. c: SEM image of a frustule of pennate diatom (cf. Navicula sp.) from Saint-Bauzile. d) SEM image of frustules forming a colony of centric diatoms (cf. Diatoma sp.) from Saint-Bauzile.
Cathodoluminescence monitoring of quantum emitter activation in hexagonal boron nitride
<p>Data from the article of S. Roux, C. Fournier, K. Watanabe, T. Taniguchi, J.-P. Hermier, J. Barjon, A. Delteil,<br> "Cathodoluminescence monitoring of quantum emitter activation in hexagonal boron nitride", <a href="https://doi.org/10.1063/5.0126357">Appl. Phys. Lett. <strong>121</strong>, 184002 (2022)</a></p> <p>[<a href="https://arxiv.org/abs/2210.05028">arXiv</a>:2210.05028]</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.