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571 results for “sheath”
Transcriptomic comparative analysis of different resistance to sheath blight in rice chromosome segment substitution lines
GEO Series GSE178395. Oryza sativa. 24 samples. Type: Expression profiling by high throughput sequencing.
C4 Photosynthesis: Gene expression in mesophyll and bundle sheath cells of bundle sheath defective2 mutant
GEO Series GSE13758. Zea mays. 24 samples. Type: Expression profiling by array.
Next Generation Sequencing based mRNA sequencing of osteogenic differentiation of human mesenchymal stem cells from hair follicle outer root sheath (MSCORS)
GEO Series GSE159140. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Single cell atlas of enthesitis reveals a mechanical strain responsing and SOX5 programmed SDC1+ sheath fibroblast in ankylosing spondylitis [CUT&TAG]
GEO Series GSE271474. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Gene expression profiling of bundle sheath and mesophyll cell types of wild-type maize seedlings.
GEO Series GSE3890. Zea mays. 24 samples. Type: Expression profiling by array.
Next Generation Sequencing based mRNA sequencing of human mesenchymal stem cells from hair follicle outer root sheath
GEO Series GSE159139. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Nerve Sheath Tumors
Whole-exome sequencing of 134 nerve sheath tumor samples with their matched normals. The raw data is contributed by Johns Hopkins University researchers funded by the Neurofibromatosis Therapeutic Acceleration Program (NTAP). The reprocessing of the raw data is managed by the NF Open Science Initiative (NF Data Portal). The original raw data was reprocessed with updated genome build and filtered to remove low confidence variant calls, and any common variants that had a gnomAD allele frequency (for any subpopulation) greater than or equal to 0.0005. The cases here are only those under the age of 40 years old.
Single-Cell Atlas of NF1 Nerve Sheath Tumors
The worst outcome of NF1 is the development of the aggressive and highly metastatic malignant peripheral nerve sheath tumors (MPNST), which transform from benign plexiform neurofibroma (PN) and lack effective treatment. In this study, we performed single-cell RNA sequencing of 63 clinically annotated NF1-associated peripheral nerve sheath tumors, including 24 PN, 34 premalignant atypical neurofibromas, and 5 MPNSTs. These results improve the ability of identifying high-risk neurofibromas and provide a unique opportunity for early detection of MPNST.
dataset related to article "The Lipid Asset Is Unbalanced in Peripheral Nerve Sheath Tumors"
<p><strong>Lipid species derived from analyses, anonymized sample series</strong></p>
DLK1 Distinguishes Subsets of NF1-Associated Malignant Peripheral Nerve Sheath Tumors with Divergent Molecular Signatures
We aimed to investigate the molecular mechanisms underlying the malignant transformation of pre-existing neurofibromas (PNST) to malignant peripheral nerve sheath tumors (MPNST) in individuals with neurofibromatosis type 1 (NF1). Our primary focus was on the role of DLK1 in this transformation process and its potential as a biomarker for diagnosis, risk assessment, and therapeutic stratification. This study consisted of a case set of peripheral nerve sheath tumor specimens, including plexiform neurofibromas, atypical neurofibromas, and MPNSTs, acquired under IRB approval at our institution. The majority of the subjects had neurofibromatosis type 1. The study found that DLK1 is significantly increased in MPNST compared to non-malignant neurofibromas. DLK1 overexpression may precede histological changes indicative of malignancy. Higher serum levels of DLK1 were observed in both mice and humans with MPNST. Divergent levels of DLK1 expression identified distinct MPNST subsets with unique molecular characteristics and potential therapeutic targets. Overexpression of DLK1 was associated with the reactivation of embryonic signatures, an immunosuppressive microenvironment, and poorer overall survival in NF1-MPNST patients.
Single-Cell Atlas of NF1 Nerve Sheath Tumors
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.