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5,931 results for “laterality”
Gene profiling of intermediolateral column, medial, and lateral motoneuron after spinal cord transection
GEO Series GSE18179. Mus musculus. 62 samples. Type: Expression profiling by array.
Gene expression of three prostate lobes, ventral prostate (VP), dorsal lateral prostate (DLP), and anterior prostate (AP), by cholesterol diet
GEO Series GSE25461. Mus musculus. 18 samples. Type: Expression profiling by array.
MicroRNAs as Regulators of Aging Processes in the Cochlear Lateral Wall of the Mouse Inner Ear (microRNA data set)
GEO Series GSE98071. Mus musculus; synthetic construct. 6 samples. Type: Non-coding RNA profiling by array.
MAPseq data of mouse corticospinal neurons with respect to laterality
GEO Series GSE277677. Mus musculus. 1 samples. Type: Other.
An MCH neuroendocrine circuit in lateral hypothalamus for bone mass regulation
GEO Series GSE239973. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Cerebellar abiotrophy in working Kelpies with a later clinical onset
GEO Series GSE102154. Canis lupus familiaris. 163 samples. Type: SNP genotyping by SNP array.
Lateral ventricle SVZ: 3xTg vs WT
GEO Series GSE60460. Mus musculus. 8 samples. Type: Expression profiling by array.
Expression data from the Lateral Habenula (LHb) and the Medial Habenula (MHb) of the mouse (C57BL/6) brain after nicotine self-administration
GEO Series GSE66453. Mus musculus; synthetic construct. 8 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Expression data from root segments of barley (Hordeum vulgare) during a transient water deficit repressing lateral root formation
GEO Series GSE67367. Hordeum vulgare. 14 samples. Type: Expression profiling by array.
Gene expression profile in SOD1-G85R transgenic mice, a mouse model of amyotrophic lateral schelosis
GEO Series GSE167974. Mus musculus. 6 samples. Type: Expression profiling by array.
Expression data from the Lateral Habenula (LHb) and the Medial Habenula (MHb) of the mouse (C57BL/6) brain after nicotine self-administration (microRNA)
GEO Series GSE66452. Mus musculus; synthetic construct. 4 samples. Type: Non-coding RNA profiling by array.
Affymetrix SNP array data for a Diffuse Large B-cell Lymphoma case with a TERT promoter variant who later developed Chronic Myelomonocytic Leukemia
GEO Series GSE133150. Homo sapiens. 1 samples. Type: Genome variation profiling by SNP array.
Relative gene expression of the lateral choroid plexus isolated from Abhd2+/+ and Abhd2-/- mice
GEO Series GSE181594. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
The KU70-SAP domain has an overlapping function with DNA-PKcs in limiting the lateral movement of KU along DNA
GEO Series GSE276069. Mus musculus. 20 samples. Type: Other.
Expression profiling of retinoic acid targets in lateral mesoderm from Xenopus laevis embryos
GEO Series GSE205827. Xenopus laevis. 18 samples. Type: Expression profiling by array.
Amyotrophic lateral sclerosis: SOD1 mouse model
GEO Series GSE2400. Mus musculus. 6 samples. Type: Expression profiling by array.
Validation of the DYALS (Dysphagia in Amyotrophic Lateral Sclerosis)
<p>Dysphagia is a common symptom during the trajectory of ALS, and it can significantly impact on the quality of life and prognosis of patients. Nowadays, no specific tool for the screening of dysphagia in ALS is validated, and the approach is heterogeneous across the Italian Centres. </p> <p>To validate the DYALS (Dysphagia in Amyotrophic Lateral Sclerosis) questionnaire, adapting the DYMUS (Dysphagia in Multiple Sclerosis) questionnaire, for the assessment of dysphagia in ALS patients, in order to uniform the evaluations across the Italian ALS network.</p> <p>We included 197 patients diagnosed with ALS following the El Escorial criteria, in sixteen Italian ALS Centres between 1st December 2019 and 1st July 2020. For each patient, we collected clinical and demographic data, and obtained ALSFRS-r score, ALSAQ-5 score, DYMUS score, and EAT-10 score. </p> <p>Across the 197 patients, the ratio M/F was 113/84, and the median age was 64 years (IQR 56-72.5). Bulbar patients were 20%, and spinal patients 80%. The median ALSFRSr total score of patients was 35 (IQR 28-39). DYALS score was statistically higher in bulbar ALS than in spinal ALS (median=6, IQR 4.5-9 vs median=1, IQR 0-5, z =6.253, p<0.0001). DYALS questionnaire showed a high internal consistency (Cronbach’s alpha=0.88). There was a statistically significant correlation between DYALS and EAT-10 (rho=0.90, p<0.0001).</p> <p>DYALS scale is reliable, manageable, and easily usable for the screening of dysphagia in ALS. It can be shared with all the Italian ALS Centres in order to collect uniform data for therapeutic strategies and clinical trials.</p>
The chronometry of symmetry detection in the lateral occipital (LO) cortex
<p>We used a chronometric transcranial magnetic stimulation (TMS) approach to study at which specific time window the lateral occipital (LO) cortex is causally involved in symmetry encoding. Healthy individuals were presented with a series of dot configurations and instructed to judge whether they were symmetric or not while receiving a double pulse of TMS over either the rLO or the vertex (baseline) at different time windows. In the present dataset mean accuracy scores (expressed as percentage of correct responses) and mean response time for correct response (expressed in millisecond) are reported for each participant.</p> <p>The results show that LO is causally involved in symmetry perception in two distinct time windows: between 130-170ms and between 210-250ms from the target onset, thus providing a causal temporal link between LO and well-known ERP components related to symmetry.</p>
Characteristics and outcomes of fetuses with laterality defects are the current outcomes better? A single center study
<p>Dataset from Fesslova V, Pluchinotta F, Brankovic J, Boschetto C, Piazza L, Inversetti A, Sigismondi C, Giorgione V, Frigiola A. Characteristics and outcomes of fetuses with laterality defects are the current outcomes better? A single center study. J Matern Fetal Neonatal Med. 2021 Feb;34(4):547-554. doi: 10.1080/14767058.2019.1610737. Epub 2019 May 20. PMID: 31106637.</p> <p>Abstract</p> <p><strong>Objective<em>:</em></strong> To analyze the more recent outcomes of fetuses with different laterality defects.<strong>Material and methods:</strong> Out of 1508 fetuses with congenital heart disease (CHD) diagnosed by echocardiography between January 1995 and December 2015, 94 (6.3%) presented abnormal visceroatrial situs: 42 till December 2002 (group 1, analyzed retrospectively) and 52 since then until December 2015 (group 2, analyzed prospectively). Twenty-one had left isomerism (Lisom), 22 right isomerism (Risom), 16 situs inversus- dextrocardia (SVI-dx), 5 situs inversus- levocardia (SVI-levo), and 30 situs solitus-dextrocardia (SSol-dx).<strong>Results:</strong> Seventy-six cases (81%) had CHD, more frequently complex atrioventricular defect. Eighteen cases showed normal heart: half of subgroups SVI-dx and SVI-levo, a third of SSol-dx. Postoperative mortality in continuing pregnancy in group 2 was 43.7 versus 40% in group 1, lower in SVs-dx (0 versus 50%) and Lisom (33.3 versus 66.7%), worse in Risom (71.4 versus 25%). Total mortality in group 2 was 48.3 versus 55% in group 1, better in Ssol-dx (37.5 versus 50%) and in Lisom (27.4 versus 71.4%). In isolated forms all but one case are alive.<strong>Conclusions:</strong> Our fetal cases presented a relevant mortality in both periods. The outcomes were slightly better in a more recent era in SSol and Lisom.What is known about this topic?Out of laterality defects, the heterotaxies (i.e. left and right isomerism) are known to be associated to a relevant mortality in fetal and neonatal cases.Heterotaxies have a variable position of the heart, but some authors evaluated only those with dextrocardia in their studies on different laterality defects.Controversial data are presented in the literature for the outcomes of fetuses with laterality defects. Many large studies analyzed the data of a very long time period in which it is opinable to compare the results of the treatment, because of a recent improved management and surgical techniques.What does this study add?Our study presents an experience of a single center with cases of different types of laterality defects observed during a routine fetal echocardiography, not only heterotaxies.The knowledge of different laterality defects and of their characteristics (association with cardiac and extracardiac anomalies or with normal heart) is useful for the prenatal counseling.We compare the postoperative and total mortality in more recent period (since 2003) with respect to the previous era (1995-2002).</p>
Dataset related to article " Behavioural and cognitive phenotypes of patients with amyotrophic lateral sclerosis carrying SOD1 mutations" (manuscript submitted)
<p>Clinical and neuropsychological anonymized data of patients involved in the study presented in the submitted article mentioned at title </p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.