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421
datasets available to search
ShareScore release 0.9.0
Dataset results
421 results for “Aorta”
Clinical Study of the Aorta-femoral Bypass and Hybrid Intervention and the Iliac Arteries With Stenting and Plasty of the Common Femoral Artery Effectiveness in Patients With the Iliac Segment and Fem
ClinicalTrials.gov study NCT02580084. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Surgical Manipulation of the Aorta and Cerebral Infarction
ClinicalTrials.gov study NCT00558779. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Impact of Aortic Geometry on Vascular Remodeling After Stent Implantation in Coarctation of the Aorta
ClinicalTrials.gov study NCT07131111. IPD Sharing: UNDECIDED. Countries: 1. Publications: 10.
Inferior Vena Cava Collapsibility Index and Caval Aorta Index for Prediction of Hypotension General Anaesthesia
ClinicalTrials.gov study NCT05368363. IPD Sharing: NO. Countries: 1. Publications: 2.
Observatory of Screening Aneurysms of the Abdominal Aorta During Echocardiography. National Epidemiological Survey
ClinicalTrials.gov study NCT01390740. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Clinical Study of Patients Treated With PuraBond Haemostatic Agent During Abdominal Aorta Open Repair
ClinicalTrials.gov study NCT05733585. IPD Sharing: NO. Countries: 1. Publications: 3.
Data from: Diagnostic value of transthoracic echocardiography in patients with coarctation of aorta: the Chinese experience in 53 patients studied between 2008 and 2012 in one major medical center
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Resuscitative endovascular balloon occlusion of the aorta (REBOA) minimal dataset
<p class="CxSpFirst"><b>Introduction</b></p> <p class="CxSpMiddle">Resuscitative endovascular balloon occlusion of the aorta (REBOA) may be used in severely injured patients with uncontrollable bleeding. However, zone dependent effects of REBOA are rarely described. We compared the short-term zone- and organ-specific microcirculatory changes in abdominal organs and the extremity during occlusion of the aorta in a standardized porcine model.</p> <p class="CxSpMiddle"><b>Methods</b></p> <p class="CxSpMiddle">Male pigs were placed under general anesthesia, for median laparotomy to expose intra-abdominal organs. REBOA placement occurred in Zone 1 (from origin left subclavian artery to celiac trunk), Zone 2 (between the coeliac trunk and most caudal renal artery) and Zone 3 (distal most caudal renal artery to aortic bifurcation). Local microcirculation of the intra-abdominal organs were measured at the stomach, colon, small intestine, liver, and kidneys. Further, the right medial vastus muscle was included for assessment. Microcirculation was measured using oxygen-to-see device (arbitrary units, A.U). Invasive blood pressure measurements were recorded in the carotid and femoral artery (ipsilateral). Ischemia/Reperfusion (I/R)-time was 10 min with complete occlusion.</p> <p class="CxSpMiddle"><b>Results</b></p> <p class="CxSpMiddle">At baseline, microcirculation of intra-abdominal organs differed significantly (p < 0.001), the highest flow was in the kidneys (208.3 ± 32.9 A.U), followed by the colon (205.7 ± 36.2 A.U.). At occlusion in Zone 1, all truncal organs showed significant decreases (p < 0.001) in microcirculation, by 75% at the colon, and 44% at the stomach. Flow-rate changes at the extremities were non-significant (n.s). During occlusion in Zone 2, a significant decrease (p < 0.001) in microcirculation was observed at the colon (-78%), small intestine (-53%) and kidney (-65%). The microcirculatory changes at the extremity were n.s. During occlusion in Zone 3, truncal and extremity microcirculatory changes were n.s.</p> <p class="CxSpMiddle"><b>Conclusion</b></p> <p>All abdominal organs showed significant changes in microcirculation during REBOA. The intra-abdominal organs react differently to the same occlusion, whereas local microcirculation in extremities appeared to be unaffected by short-time REBOA, regardless of the zone of occlusion.</p>
Differential gene expression in aortae isolated from mice consuming normal water or that containing polystyrene beads
<p>Microplastics (MP) derived from the degradation of larger polymers or synthesized for commercial purposes are ubiquitous in the environment and have found their way into food supplies and water systems where human consumption is inevitable. We hypothesize that MP ingestion promotes CVD risk and atherosclerosis. To test this idea, we supplied ApoE-/- mice with normal chow and either normal water or that containing polystyrene (PS) beads (0.5 μm in diameter; dose of 1 μg/ml). After 20 weeks of exposure, we evaluated lesion formation and gene expression data in cardiovascular tissue. We observed that mice consuming the PS water had increased lesion size compared to those mice consuming normal water. but no changes in plasma lipids or cytokines. An RNAseq analysis of collected aortae identified 1622 differentially expressed genes between the groups, consisting of 414 that were up-regulated and 1208 that were down-regulated. </p>
Minimally invasive Aortic Valve and Ascending Aorta Replacement
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Endovascular Graft Anchoring Different Regions of Ascending Aorta in the Treatment of Ascending Aortic Dissection
ClinicalTrials.gov study NCT04544579. IPD Sharing: Not stated. Countries: 0. Publications: 1.
GORE TAG® Thoracic Endoprosthesis - 45 mm for the Treatment of Aneurysms of the Descending Thoracic Aorta
ClinicalTrials.gov study NCT00608829. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Prevention of Acute Kidney Injury by Erythropoietin in Thoracic Aorta Surgery With Hypothermic Cardiac Arrest
ClinicalTrials.gov study NCT01369732. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Changes in Elastic Properties of Descending Thoracic Aorta After Ascending Aorta Replacement
ClinicalTrials.gov study NCT03817008. IPD Sharing: NO. Countries: 0. Publications: 1.
Statins and Endothelial Function in Patients With Coarctation of the Aorta
ClinicalTrials.gov study NCT00767572. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Biomarkers in Thoracic Aorta Surgery
ClinicalTrials.gov study NCT04689139. IPD Sharing: NO. Countries: 1. Publications: 0.
CRD007 for the Treatment of Abdominal Aorta Aneurysm (The AORTA Trial)
ClinicalTrials.gov study NCT01354184. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Resuscitative endovascular balloon occlusion of the aorta (REBOA) minimal dataset
Open the record for dataset details and reuse information.
Differential gene expression in aortae isolated from mice consuming normal water or that containing polystyrene beads
Open the record for dataset details and reuse information.
RNA sequencing data describing transcriptional changes in aorta of ApoE-/- mice after alpha 7 nicotinic acetylcholine receptor (α7nAChR) stimulation.
GEO Series GSE131162. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.