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84 results for “Biomimetic”
Tuning the 3D microenvironment of reprogrammed tubule cells enhances biomimetic modeling of polycystic kidney disease
GEO Series GSE184531. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Functional regeneration and repair of tendons using biomimetic scaffolds loaded with recombinant Periostin
GEO Series GSE158342. Rattus norvegicus. 6 samples. Type: Expression profiling by array.
Spaceflight analogue culture enhances the host-pathogen interaction between Salmonella and a 3-D biomimetic intestinal co-culture model
GEO Series GSE146347. Salmonella enterica subsp. enterica serovar Typhimurium; Homo sapiens. 72 samples. Type: Expression profiling by high throughput sequencing.
Direct analysis of the embryo-maternal interactions in a 3D biomimetic implantation niche
GEO Series GSE151329. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche
GEO Series GSE89479. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Biomimetic fractal topography enhances podocyte maturation in vitro
GEO Series GSE298416. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
Tuning the 3D-microenvironment of reprogrammed tubule cells enhances biomimetic modeling of polycystic kidney disease.
GEO Series GSE148840. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Biomimetic Cell Stimulation with Graphene Oxide Antigen Presenting Platform (GO-APP) for Developing T Cell-Based Therapies [RNA-Seq]
GEO Series GSE233259. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Biomimetic Cell Stimulation with Graphene Oxide Antigen Presenting Platform (GO-APP) for Developing T Cell-Based Therapies
GEO Series GSE233291. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Data from: Kinetic study of catalytic CO2 hydration by metal-substituted biomimetic carbonic anhydrase model complexes
The rapid rise of the CO2 level in the atmosphere has spurred the development of CO2 capture methods such as the use of biomimetic complexes that mimic carbonic anhydrase. In this study, model complexes with tris(2-pyridylmethyl)amine (TPA) were synthesized using various transition metals (Zn2+, Cu2+ and Ni2+) to control the intrinsic proton-donating ability. The pKa of the water coordinated to the metal, which indicates its proton-donating ability, was determined by potentiometric pH titration and found to increase in the order [(TPA)Cu(OH2)]2+ < [(TPA)Ni(OH2)]2+ < [(TPA)Zn(OH2)]2+. The effect of pKa on the CO2 hydration rate was investigated by stopped-flow spectrophotometry. Because the water ligand in [(TPA)Zn(OH2)]2+ had the highest pKa, it would be more difficult to deprotonate it than those coordinated to Cu2+ and Ni2+. It was therefore expected that the complex would have the slowest rate for the reaction of the deprotonated water with CO2 to form bicarbonate. However, it was confirmed that [(TPA)Zn(OH2)]2+ actually had the fastest CO2 hydration rate because the substitution of bicarbonate with water (bicarbonate release) occurred easily.
Tissue-engineered oral epithelial barrier for dental material testing: towards establishing in vitro biomimetic models - Underlying data
<p>Underlying CT data of "<strong>Tissue-engineered oral epithelial barrier for dental material testing: towards establishing <em>in vitro </em>biomimetic models</strong>"<br><a href="https://doi.org/10.1089/ten.tec.2024.0154">https://doi.org/10.1089/ten.tec.2024.0154</a></p> <p>Foteini Machla a, Paraskevi Kyriaki Monou b, c, Chrysanthi Bekiari d, Dimitrios Andreadis e Evangelia Kofidou d, , Emmanouel Panteris f, Orestis L. Katsamenis g, h, Maria Kokoti a, Petros Koidis a, Imad About i, Dimitrios Fatourosb, c, Athina Bakopoulou a</p> <p>a Department of Prosthodontics, Tissue Engineering Core Unit, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece</p> <p>b Department of Pharmaceutical Technology, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece</p> <p>c Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Thessaloniki 57001, Greece</p> <p>d Laboratory of Anatomy and Histology, Veterinary School, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece</p> <p>e Department of Oral Medicine/Pathology, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece</p> <p>f Department of Botany, School of Biology, Faculty of Sciences, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece</p> <p>g μ-VIS X-ray Imaging Centre, Faculty of Engineering and the Environment, University of Southampton, Southampton SO17 1BJ, United Kingdom</p> <p>h Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, United Kingdom UK</p> <p>i Centre National de la Recherche Scientifique, Institute of Movement Sciences, Aix Marseille University, Marseille 13385, France</p> <p> </p> <p><strong>Measurement of ΤΕΟΕ thickness</strong></p> <p>X-ray computed micro-tomography (μCT) as employed to examine the microstructure of the paraffin-embedded tissue engineered oral epithelium (TEOE), enabling comprehensive 3D assessment of thickness using volumetric analysis (cf. supplementary for imaging parameters) (11). Imaging was conducted using an isotropic voxel-edge of 6.0 μm. Local Thickness was carried out in 3D using the “Volume Thickness Map” tool within Dragonfly software (cf. supplementary), allowing for the visualization and quantification of the spatial distribution and variability of tissue thickness.</p> <p>Imaging was conducted at the University of Southampton’s μ-VIS X-ray Imaging Centre ( https://muvis.org ) / 3D X-ray Histology facility, utilizing a customised μCT scanner optimisedfor intricate histological analyses(1), based on Nikon’s XTH225ST system (Nikon Metrology, UK). Operating parameters were set at 80 kVp / 86 μA (6.88 W), with a source-to-object distance of 37.5 mm and a source-to-detector distance of 937.4 mm, resulting in a magnification factor of 25x and an isotropic voxel-edge of 6.0 μm. Imaging acquisition involved the collection of 4001 projections using a 2850 x 2850 dexels detector, by averaging 4 frames per projection, with an exposure time of 500 ms per projection.</p> <p>Visualisation and analysis of the reconstructed dataset was done using Dragonfly software (Comet Technologies Canada Inc.; software accessible at http://www.theobjects.com/dragonfly). Assessment of Local Thickness was carried out in 3D using the “Volume Thickness Map” tool within Dragonfly software, following segmentation of the tissue layer. Local thickness analysis allowed for the visualization and quantification of the spatial distribution and variability of thickness within the tissue engineered oral epithelium (TEOE).</p> <p>Visual representation of local thickness histograms was employed to elucidate the distribution of thickness throughout the TEOE. These histograms effectively illustrate the number of voxels associated with specific cross-sectional thickness, offering both a graphical depiction of the variation in thickness across the tissue sample, and a quantitative measure of the average thickness of the specimen.</p> <p>It's worth noting, the volumetric and non-destructive nature of the technique enabled whole-block imaging, which proved crucial in addressing challenges arising from tissue sample shrinkage. This shrinkage, a consequence of dehydration during the fixation process, can occur in some cases and lead led to the specimen wrapping. While wrapping is not a common occurrence, this analysis method allowed for the evaluation of challenging-shaped specimens, such as the wrapped one presented in Figure 4. Unlike conventional 2D methods such as classical histology, which rely on the angle of slicing and encounter limitations when dealing with non-perfectly perpendicular slicing, μCT-based XRH enables analysis of all specimens, including those with complex shapes.</p> <p> </p>
Biomimetic Hydroxyapatite Toothpaste and Mouthwash for Reducing Dental Sensitivity
ClinicalTrials.gov study NCT07057141. IPD Sharing: NO. Countries: 1. Publications: 0.
Retrospective Evaluation of a Novel Biomimetic Synthetic Bone Substitute (Creos® Syntogain)
ClinicalTrials.gov study NCT06473545. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of Different Biomimetic Materials on White Spot Lesions in Enamel
ClinicalTrials.gov study NCT05001035. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis
ClinicalTrials.gov study NCT05631197. IPD Sharing: NO. Countries: 1. Publications: 0.
Evaluation of Biomimetic Mineralization Plus Soft Laser Irradiation in Dentin Hypersensitivity Management
ClinicalTrials.gov study NCT06829277. IPD Sharing: NO. Countries: 1. Publications: 0.
Research on the Development and Clinical Evaluation of Biomimetic Abutments
ClinicalTrials.gov study NCT06870955. IPD Sharing: NO. Countries: 1. Publications: 0.
Digital, Conventional, And Biomimetic Approaches for Restoring Endodontically Treated Teeth
ClinicalTrials.gov study NCT06717230. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Domiciliary Management of Dental Erosion in Patients With GERD With Biomimetic Hydroxyapatite
ClinicalTrials.gov study NCT05371717. IPD Sharing: NO. Countries: 1. Publications: 0.
Clinical and Radiographic Evaluation of Three Biomimetic Materials in Pulp Therapy of Immature Young Permanent Teeth "A Randomized Controlled Clinical Trial"
ClinicalTrials.gov study NCT07207382. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.