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122
datasets available to search
ShareScore release 0.9.0
Dataset results
122 results for “Brain dynamics”
Multimodal Exercise Effect on Brain Dynamics, Cognitive Functioning and Physical Fitness
ClinicalTrials.gov study NCT04189458. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Redox regulation of brain selective kinases BRSK1/2: Implications for dynamic control of the eukaryotic AMPK family through Cys-based mechanisms
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Data from: Stabilizing brain-computer interfaces through alignment of latent dynamics
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Data from: Brain states govern the spatio-temporal dynamics of resting-state functional connectivity
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Data from: Dynamics in brain activation and behaviour in acute and repeated social defensive behaviour
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Therapeutic Deep Brain Stimulation Disrupts Subthalamic Nucleus Activity Dynamics in Parkinsonian Mice
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Unconsciousness reconfigures modular brain network dynamics
<p>Time-dependent adjacency matrices per state of consciousness</p>
Data from: Comparative dynamics of microglialand glioma cell motility at the infiltrative margin of brain tumours
Microglia are a major cellular component of gliomas, and abundant in the centre of the tumour and at the infiltrative margins. While glioma is a notoriously infiltrative disease, the dynamics of microglia and glioma migratory patterns have not been well characterized. To investigate the migratory behaviour of microglia and glioma cells at the infiltrative edge, we performed two-colour time-lapse fluorescence microscopy of brain slices generated from a platelet-derived growth factor-B (PDGFB)-driven rat model of glioma, in which glioma cells and microglia were each labelled with one of two different fluorescent markers. We used mathematical techniques to analyse glioma cells and microglia motility with both single cell tracking and particle image velocimetry (PIV). Our results show microglia motility is strongly correlated with the presence of glioma, while the correlation of the speeds of glioma cells and microglia was variable and weak. Additionally, we showed that microglia and glioma cells exhibit different types of diffusive migratory behaviour. Microglia movement fit a simple random walk, while glioma cell movement fits a super diffusion pattern. These results show that glioma cells stimulate microglia motility at the infiltrative margins, creating a correlation between the spatial distribution of glioma cells and the pattern of microglia motility.
Dysfunctions-of-Multiscale-Dynamic-Brain-Functional-Networks-in-Subjective-Cognitive-Decline
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Codes and images associated with "Neuronal dynamics orchestrate cerebrospinal fluid perfusion and brain clearance"
<p>MATLAB scripts and representative images associated with the publication. </p>
Locus Coeruleus firing patterns selectively modulate brain activity and dynamics
<p>This dataset supports the manuscript entitled 'Locus Coeruleus firing patterns selectively modulate brain activity and dynamics' (https://doi.org/10.1101/2022.08.29.505672). Please refer to this manuscript for detailed information. </p> <p>The dataset contains a total of 81 functional (GE-BOLD) and 30 anatomical (T1-weighted) scans of ChR2-expressing C57BL/6-Tg(<em>Dbh</em>-iCre)1Gsc mice in NIFTI format, multiplied by 10. Mice were optogenetically stimulated with blue light in the right Locus Coeruleus in a 3Hz tonic, 5Hz tonic, and 15Hz burst pattern. Sham stimulation entailed red light stimulation at a 5Hz tonic frequency. The 'StimulationProtocol' text file specifies the precise onset (in seconds, minus 10 seconds for dummy scans) and duration (in seconds) of the different optogenetic stimulation protocols during a 1440 seconds functional scan. The 'SubjectDetails' file lists the subject IDs, their gender, their genotype, the stimulation type of functional scans, and their associated anatomical scan.</p>
Raw data accompanying "Arousal effects on oscillatory dynamics in the non-human primate brain"
<p>Raw local field potentials in two NHPs during eyes closed, low saccade, and high saccade task-free activity.</p> <p>Data and code to produce key figures. </p>
Data from: Stimulation-based control of dynamic brain networks
The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to enhance human performance. Despite the growing interest in brain stimulation as a form of neuromodulation, much remains unknown about the network-level impact of these focal perturbations. To study the system wide impact of regional stimulation, we employ a data-driven computational model of nonlinear brain dynamics to systematically explore the effects of targeted stimulation. Validating predictions from network control theory, we uncover the relationship between regional controllability and the focal versus global impact of stimulation, and we relate these findings to differences in the underlying network architecture. Finally, by mapping brain regions to cognitive systems, we observe that the default mode system imparts large global change despite being highly constrained by structural connectivity. This work forms an important step towards the development of personalized stimulation protocols for medical treatment or performance enhancement.
Processed MEG data used for revealing dynamic brain reconfiguration using MAPPER
<p>This is MEG data used for topological data analysis for revealing dynamic brain reconfiguration.</p>
Brain Dynamics Involved in Generating Tics and Controlling Voluntary Movement
ClinicalTrials.gov study NCT00056420. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Data from: Stimulation-based control of dynamic brain networks
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Data from: Comparative dynamics of microglialand glioma cell motility at the infiltrative margin of brain tumours
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Temporal and Spatial Transcriptomic Dynamics across Brain Development in Xenopus laevis tadpoles
GEO Series GSE183193. Xenopus laevis. 30 samples. Type: Expression profiling by high throughput sequencing.
DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain [RNA-seq]
GEO Series GSE140120. Xenopus tropicalis. 12 samples. Type: Expression profiling by high throughput sequencing.
Dynamically regulated transcription factors are encoded by highly unstable mRNAs in the Drosophila larval brain
GEO Series GSE219202. Drosophila melanogaster. 15 samples. Type: Expression profiling by high throughput sequencing; Other; Third-party reanalysis.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.