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250
datasets available to search
ShareScore release 0.9.0
Dataset results
250 results for “Clinical biomarker”
Assessing the Prognosis of TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for HCC by Using Clinical and Imaging Biomarkers
ClinicalTrials.gov study NCT05278195. IPD Sharing: NO. Countries: 1. Publications: 5.
Clinical Biomarkers in Alpha-mannosidosis
ClinicalTrials.gov study NCT02141503. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Follow-up of Osteo-articular Biomarkers After Spa Therapy in a Population With Knee Osteoarthritis and Their Correlation With the Clinical Evolution
ClinicalTrials.gov study NCT04308369. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Clinical Study of Microchimerism and cfDNA as Biomarkers for Acute Rejection After Organ Transplantation
ClinicalTrials.gov study NCT03255265. IPD Sharing: Not stated. Countries: 1. Publications: 28.
Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex
ClinicalTrials.gov study NCT02098759. IPD Sharing: Not stated. Countries: 8. Publications: 1.
Effect of Enalapril and Losartan Association Therapy on Proteinuria and Inflammatory Biomarkers in Diabetic Nephropathy: a Clinical Trial on Type 2 Diabetes Mellitus
ClinicalTrials.gov study NCT00419835. IPD Sharing: Not stated. Countries: 1. Publications: 3.
A Biomarker-implemented Clinical Study Evaluating Mutations in MET and TP53 in a Population of Treatment-refractory Squamous Cell Carcinoma
ClinicalTrials.gov study NCT04533321. IPD Sharing: NO. Countries: 1. Publications: 2.
MRI Biomarkers in as Predictor of Clinical Endpoints in Pediatric Autoimmune Liver Disease
ClinicalTrials.gov study NCT03178630. IPD Sharing: NO. Countries: 1. Publications: 0.
Biomarkers of Acute Stroke in Clinic
ClinicalTrials.gov study NCT03897478. IPD Sharing: NO. Countries: 1. Publications: 1.
Assessing the Clinical Effectiveness of Serum Biomarkers in the Diagnosis of Metastatic Uveal Melanoma
ClinicalTrials.gov study NCT01438658. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Novel Vascular Biomarkers Behaviour and Clinical Value in Heart Failure and CRT
ClinicalTrials.gov study NCT02541773. IPD Sharing: Not stated. Countries: 1. Publications: 19.
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing
ClinicalTrials.gov study NCT04394871. IPD Sharing: NO. Countries: 1. Publications: 2.
Study of Pancreatic Enzymes in the Drains as Early Biomarkers of Post-operative Pancreatic Fistula and Its Clinical Repercussions
ClinicalTrials.gov study NCT02784990. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Biomarker Platform (Virtual Nodule Clinic) for the Management of Indeterminate Pulmonary Nodules
ClinicalTrials.gov study NCT06638398. IPD Sharing: NO. Countries: 1. Publications: 0.
The Role of 1.5-anhydro-D-glucitol as Clinical Biomarkers of Hypoglycemia in Patients With Diabetes
ClinicalTrials.gov study NCT02068300. IPD Sharing: NO. Countries: 1. Publications: 1.
Study to Identify Biomarkers of Clinical Response to Aflibercept in Patients With Metastatic Colorectal Cancer
ClinicalTrials.gov study NCT02045030. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors
ClinicalTrials.gov study NCT04526587. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Data from: Identification of biomarkers for Barcelona Clinic Liver Cancer staging and overall survival of patients with hepatocellular carcinoma
Open the record for dataset details and reuse information.
Comprehensive investigation of circulating biomarkers and their causal role in atherosclerosis-related risk factors and clinical events
<p><strong>Background</strong>: Circulating biomarkers have been previously associated with atherosclerosis-related risk factors, but the nature of these associations is incompletely understood.</p> <p><strong>Methods</strong>: We performed multivariable-adjusted regressions and 2-sample Mendelian randomization analyses to assess observational and causal associations of 27 circulating biomarkers with 7 cardiovascular traits in up to 451 933 participants of the UK Biobank.</p> <p><strong>Results</strong>: After multiple-testing correction (alpha=1.3Å~10−4), we found a total of 15, 9, 21, 22, 26, 24, and 26 biomarkers strongly associated with coronary artery disease, ischemic stroke, atrial fibrillation, type 2 diabetes, systolic blood pressure, body mass index, and waist-to-hip ratio; respectively. The Mendelian randomization analyses confirmed strong evidence of previously suggested causal associations for several glucose- and lipid-related biomarkers with type 2 diabetes and coronary artery disease. Particularly interesting findings included a protective role of IGF-1 (insulin-like growth factor 1) in systolic blood pressure, and the strong causal association of lipoprotein(a) in coronary artery disease development (β, −0.13; per SD change in exposure and outcome and odds ratio, 1.28; P=2.6Å~10−4 and P=7.4Å~10−35, respectively). In addition, our results indicated a causal role of increased ALT (alanine aminotransferase) in the development of type 2 diabetes and hypertension (odds ratio, 1.59 and β, 0.06, per SD change in exposure and outcome; P=4.8Å~10−11 and P=6.0Å~10−5). Our results suggest that it is unlikely that CRP (C-reactive protein) and vitamin D play causal roles of any meaningful magnitude in development of cardiometabolic disease.</p> <p><strong>Conclusions</strong>: We confirmed and extended known associations and reported several novel causal associations providing important insights about the cause of these diseases, which can help accelerate new prevention strategies.</p>
Accuracy of EEG Biomarkers in the Detection of Clinical Outcome in Disorders of Consciousness after Severe Acquired Brain Injury: Preliminary Results of a Pilot Study Using a Machine Learning Approach
<p>Dataset for the accepted publication: "Accuracy of EEG Biomarkers in the Detection of Clinical Outcome in Disorders of Consciousness after Severe Acquired Brain Injury: Preliminary Results of a Pilot Study Using a Machine Learning Approach"</p> <p> </p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.