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223 results for “Danio rerio”
Figure 1 in Use of melatonin as an inhibitor of apoptotic process for cryopreservation of zebrafish (Danio rerio) embryos
Figure 1. Representative scanning electron micrographs of vitrified and non-vitrified zebrafish (Danio rerio) embryos. (A) Control group; (B-D) Vitrified with 0, 1 µM and 1 mM melatonin respectively. Arrows, arrow head and asterisk point to invaginations and perforations, rupture of the vitelline membrane and wrinkling of the epidermis respectively.
Figure 5 in The ontogeny and homology of the Weberian apparatus in the zebrafish Danio rerio (Ostariophysi: Cypriniformes)
Figure 5. Illustration of the differentiating saddle-shaped complex cartilage from a dorsolateral aspect (LU F.082313, 10.5 mm SL). Associated neural arches are not shown. Anterior to the left.
Figure 3 in The ontogeny and homology of the Weberian apparatus in the zebrafish Danio rerio (Ostariophysi: Cypriniformes)
Figure 3. Complex cartilage and neural arch three association in (A). Cleared and stained specimen (LU F.082315, 4.9 mm SL) and (B) histological transverse section (LU F.082320, 5.7 mm TL).
Figure 4 in The ontogeny and homology of the Weberian apparatus in the zebrafish Danio rerio (Ostariophysi: Cypriniformes)
Figure 4. Photomicrograph of transverse section through (A) occipital region showing the connective tissue perineural tube surrounding the neural tube (LU F.082320, 5.7 mm TL). (B) Photograph of vertebra one showing the developing fibrocartilage pad (LU F.082320, 5.7 mm TL).
Figure 1 in The ontogeny and homology of the Weberian apparatus in the zebrafish Danio rerio (Ostariophysi: Cypriniformes)
Figure 1. Weberian apparatus of Opsariichthys bidens. Modified from Fink & Fink (1981). Bone is stippled and cartilage is shaded black. Anterior to the left.
Differential reproductive plasticity under thermal variability in a freshwater fish (Danio rerio)
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Effects of trabectedin in the zebrafish Danio rerio: from cells to larvae
<p>These archives contain the original data set for the research article "Effects of trabectedin in the zebrafish Danio rerio: from cells to larvae"<br> </p> <p><strong>FACS_ZFL_cells_Trabectedin.rar</strong> </p> <p>Contains the original data regarding cells morphology evaluated by flow cytometry (Becton Dickinson FACScan).</p> <p><strong>Original data set_</strong></p> <p>This archive contains the original data tables for the research article "Effects of trabectedin in the zebrafish Danio rerio: from cells to larvae"</p> <p><strong>Original data set_Spreadsheet Trypan Blue test_in vitro</strong></p> <p>Cells viability on ZFL exposed to trabectedin measured by Trypan blue dye exclusion method</p> <p><strong>Original data set_Spreadsheet MTT test_in vitro</strong></p> <p>Cytotoxicity of trabectedin and doxorubicin (positive control) against ZFL cells as analyzed by the MTT assay</p> <p><strong>Original data set_Spreadsheet Survival_in vivo</strong></p> <p>Percentage of zebrafish embryos under trabectedin exposure</p> <p><strong>Original data set_Spreadsheet Abnormalities_in vivo</strong></p> <p>Percentage of abnormalities (somite alteration, pericardial edema, tail malformations, lack of equilibrium) of zebrafish embryos under trabectedin exposure</p> <p><strong>Original data set_Spreadsheet Swimming behavior_in vivo</strong></p> <p>Total distance covered and mean velocity by zebrafish larvae (120 hpf) after exposure to trabectedin</p> <p> </p> <p> </p>
Differences in oxidative status explain variation in thermal acclimation capacity between individual zebrafish (Danio rerio)
1. Evolutionary theory predicts that the capacity to acclimate should be favoured in variable environments. However, perfect compensation for thermal variation is rare and the capacity for thermal acclimation can vary considerably between individuals within natural populations. This variation may be explained by costs associated with acclimation, but it is not clear what these costs are. 2. We tested the hypothesis that oxidative stress is a cost of acclimation that could explain the variation between individuals in acclimation capacity. We acclimated individual mosquitofish (Gambusia holbrooki, n = 416) to 18oC and 28oC sequentially, and determined swimming performance at each temperature to evaluate their acclimation capacity. Fish were then acclimated to either cold (18oC) or warm (28oC) conditions, and we increased antioxidant capacities of a subset of fish experimentally by administering N-acetyl cysteine (NAC). We measured H2O2 production, catalase antioxidant activities, and oxidative damage to proteins and membranes. 3. We show that there is significant variation in acclimation capacity between individuals, and that there is a trade-off between acclimation capacity and swimming performance in warm conditions. Mean swimming performance across both acclimation temperatures increased with increasing acclimation capacity, but the increase was small biologically. Hence, greater thermal plasticity (high acclimation capacity) resulted in only minor performance benefits across acclimation conditions. We verified this rather surprising result in replicate populations grown in outdoor mesocosms. 4. ROS production, antioxidant activities, and oxidative damage were higher in cold-acclimated fish, and particularly in those fish with low capacity for acclimation. However, experimentally increasing antioxidant capacities with NAC alleviated these changes to oxidative status, suggesting a causal relationship. Hence, oxidative stress may be a cost that constrains the capacity for acclimation. Together, the performance trade-off and oxidative cost indicate that phenotypic plasticity is not always advantageous in variable environments, and instead bet-hedging may be a more beneficial strategy, particularly in short-lived species.
Data for: Feeding frequency does not interact with BPA exposure to influence metabolism of behaviour in zebrafish (Danio rerio)
<p><span>Resource limitation can constrain energy (ATP) production, and thereby affect locomotion and behaviour such as exploration of novel environments and boldness. Consequently, ecological processes such as dispersal and interactions within and between species may be influenced by food availability. Energy metabolism, and behaviour are regulated by endocrine signaling, and may therefore be impacted by endocrine disrupting compounds (EDCs) such as bisphenol A (BPA) derived from plastic manufacture and pollution. It is important to determine the impacts of these novel environmental contexts to understand how human activity alters individual physiology and behaviour and thereby populations. Our aim was to determine whether BPA exposure interacts with feeding frequency to alter metabolism and behaviour. In a fully factorial experiment, we show that low feeding frequency reduced zebrafish (<em>Danio rerio</em>) mass, condition, resting metabolic rates, total distance moved and speed in a novel arena, as well as anxiety indicated by the number of times fish returned to a dark shelter. However, feeding frequency did not significantly affect maximal metabolic rates, aerobic scope, swimming performance, latency to leave a shelter, or metabolic enzyme activities (citrate synthase and lactate dehydrogenase). Natural or anthropogenic fluctuation in food resources can therefore impact energetics and movement of animals with repercussions for ecological processes such as dispersal. BPA exposure reduced LDH activity and body mass, but did not interact with feeding frequency. Hence, behaviour of adult fish is relatively insensitive to disruption by BPA. However, alteration of LDH activity by BPA could disrupt lactate metabolism and signalling and together with reduction in body mass could affect size-dependent reproductive output. BPA released by plastic manufacture and pollution can thereby impact conservation and management of natural resources. </span></p>
scRNAseq of Danio rerio telencephalon
<p>scRNA-sequencing dataset of Danio rerio telencephalon is provided for easier access as .rds objects:</p><ul><li>telencephalon_cells.rds contains all cells and their respective supercluster-ID</li><li>neurons.subset.rds contains all neuronal cell types and their subcluster ID</li></ul>
Fig. 23. Danio rerio, 35.6 in The non-native freshwater fishes of Singapore: an annotated compilation
Fig. 23. Danio rerio, 35.6 mm SL, Mount Pleasant.
Data from: The contribution of mutation to variation in temperature-dependent sprint speed in zebrafish, Danio rerio
<p>The contribution of new mutations to phenotypic variation, and the consequences of this variation for individual fitness, are fundamental concepts for understanding genetic variation and adaptation. Here, we investigated how mutation influenced variation in a complex trait in zebrafish, <em>Danio</em> <em>rerio</em>. Typical of many ecologically relevant traits in ectotherms, swimming speed in fish is temperature-dependent, with evidence of adaptive evolution of thermal performance. We chemically induced novel germline point mutations in males and measured sprint speed in their sons at six temperatures (between 16<span>°C</span> and 34<span>°C</span>). Heterozygous mutational effects on speed were strongly positively correlated among temperatures, resulting in statistical support for only a single axis of mutational variation, reflecting temperature-independent variation in speed (faster-slower mode). These results suggest pleiotropic effects on speed across different temperatures, however, spurious correlations arise via linkage, or heterogeneity in mutation number when mutations have consistent directional effects on each trait. Here, mutation did not change mean speed, indicating no directional bias in mutational effects. The results contribute to emerging evidence that mutations may predominantly have synergistic cross-environment effects, in contrast to conditionally neutral or antagonistic effects which underpin thermal adaptation. We discuss several aspects of experimental design that may affect resolution of mutations with non-synergistic effects.</p>
TBT exposure dataset of the manuscript "Assessment of endocrine disruptors effects on zebrafish (Danio rerio) embryos by untargeted LC-HRMS metabolomic analysis"
<p><strong>Raw LC-HRMS data of the TBT exposure of zebrafish embryos (for more details see https://doi.org/10.1016/j.scitotenv.2018.03.369)</strong></p> <p>The exposure protocol involved zebrafish embryos exposed in groups of 20 to various concentrations of chemical compounds, with five replicates per treatment. The concentrations ranged from the lowest observed effect concentrations (LOECs) to control levels. After exposure, embryos were collected, washed, frozen, and stored. Metabolites were extracted from individual embryo pools using methanol and methionine sulfone. The extraction process included vortexing, sonication, and centrifugation, followed by addition of water and chloroform. The aqueous fraction was dried and reconstituted using acetonitrile-water solution. Liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) was used for analysis. Chromatographic separations were carried out on a hydrophilic interaction liquid chromatography (HILIC) column. Mass spectrometry was performed using an Orbitrap mass spectrometer with electrospray ionization in positive and negative modes. The mass spectra were acquired at high resolution, and fragmentation scans were used for metabolite identification. The overall process aimed to analyze the metabolomic profile of zebrafish embryos exposed to different chemical concentrations.</p> <p><strong>Data files</strong></p> <blockquote> <p>TBT ESI+ (tbt_pos.rar) - CDF files</p> <p>- QC (4 replicates)</p> <p>- Control (5 replicates)</p> <p>- TBT 3 nM (5 replicates)</p> <p>- TBT 10 nM (5 replicates)</p> <p>- TBT 30 nM (5 replicates)</p> <p>- TBT 100 nM (5 replicates)</p> </blockquote> <p> </p> <blockquote> <p>TBT ESI- (tbt_neg.rar) - CDF files</p> <p>- QC (6 replicates)</p> <p>- Control (5 replicates)</p> <p>- TBT 3 nM (5 replicates)</p> <p>- TBT 10 nM (5 replicates)</p> <p>- TBT 30 nM (5 replicates)</p> <p>- TBT 100 nM (5 replicates)</p> </blockquote>
Original dataset of the study entitled Effects of trabectedin on the hepatic metabolism of adult zebrafish Danio rerio
<p>Original chromatograms (.qgd files) and normalized peak areas of the annotaded metabolites (.csv file)</p>
Original dataset of the study entitled Effects of trabectedin on the gut bacterial communities structure of the zebrafish Danio rerio
<p><strong>Original data set_Spreadsheet Genus</strong></p> <p>Relative abundance of the bacterial genus found on the gut of adult male zebrafish under trabectedin exposure</p> <p><strong>Original data set_Spreadsheet Family</strong></p> <p>Relative abundance of the bacterial family found on the gut of adult male zebrafish under trabectedin exposure</p> <p><strong>Original data set_Spreadsheet Order</strong></p> <p>Relative abundance of the bacterial order found on the gut of adult male zebrafish under trabectedin exposure</p> <p><strong>Original data set_Spreadsheet Class</strong></p> <p>Relative abundance of the bacterial class found on the gut of adult male zebrafish under trabectedin exposure</p> <p><strong>Original data set_Spreadsheet Phylum</strong></p> <p>Relative abundance of the bacterial phylum found on the gut of adult male zebrafish under trabectedin exposure</p>
The impact of methanol on behaviour: Dataset from zebrafish (Danio rerio) behavioural research
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Data from: The contribution of mutation to variation in temperature-dependent sprint speed in zebrafish, Danio rerio
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Data from: Water flow impacts group behavior in zebrafish (Danio rerio)
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Data for: Feeding frequency does not interact with BPA exposure to influence metabolism of behaviour in zebrafish (Danio rerio)
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Increased physical activity does not improve obesity-induced decreases in muscle quality in zebrafish (Danio rerio)
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
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The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
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