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210 results for “Data Reliability”
Data from: Reliable and fast genotyping protocol for galactosylceramidase (GALC) in the Twitcher (Twi) mouse
<p><span>The Twitcher (Twi) mouse is a neurological Krabbe disease (KD, or globoid cell leukodystrophy) spontaneous mutant line. The genome of the Twi mouse presents a single nucleotide polymorphism (SNP), leading to an enzymatically inactive galactosylceramidase (GALC) protein and causing KD. In this context, mouse Twi genotyping is an essential step in KD research. To date,</span><span> the genotyping method used is labor-intensive and often drives ambiguous results</span><span>.</span><span> </span><span>Here, we evaluate a novel protocol for the genotype determination of GALC mutation status in Twi mice based on the allele-discrimination real-time polymerase chain reaction (PCR).</span><br><br><span>DNA is extracted from Twi mice (n = 20, pilot study; n = 120, verification study) and control group (n = 10, pilot study; n = 30 verification study) and assessed by allele-discrimination real-time PCR to detect SNP c.355G>A.</span><br><br><span>Using the allele-discrimination PCR, all the samples are identified correctly with the genotype GG (wild-type, WT), GA (heterozygote, HET), or AA (homozygote, HOM) by the first analysis and no animals were not genotyped.</span><br><br><span>We demonstrated that this novel method can be used to distinguish timely, accurately and without </span><span>ambiguity among </span><span>HOM, WT, and HET animals. This protocol represents a great opportunity to increase accuracy and speed in KD research.</span></p>
Data from: Variation in the strength of female mate preference for male size supports the signal reliability hypothesis
<p>Both sexually selected traits and mate preferences for these traits can be condition dependent, yet how variation in preferred traits could select for condition dependent preferences has rarely been examined. The signal reliability hypothesis predicts that mate preferences vary across environments in relation to the reliability of the information preferred traits provide in those environments. Extensive variation in copy number of the <em>mc4r</em> gene on Y chromosome is correlated with adult male size in <em>Xiphophorus multilineatus</em>, when males stop growing. This genetic variation allowed us to use a split-sibling design to show that male size is more variable, and thus likely to provide reliable information about male genotype, when males were reared in a warm as compared to cold environment. Females reared in the warm environment had stronger mate preferences for male size. Understanding how the reliability of male traits can select for conditional variation in the strength of the female mate preferences will further our discovery of adaptive mate preferences. For example, the relationship between the strength of a female's mate preference and their growth rates supports previous work hypothesizing disassortative mating in relation to growth rates to mitigate a documented growth-mortality tradeoff in this species.</p>
Data-set for "Reliability and operation cost of underdamped memories during cyclic erasures" (Research Article, No. apxr.202300074) to Advanced Physics Research.
<p><strong>Dataset for the article: "Reliability and operation cost of underdamped memories during cyclic erasures" (Research Article, No. apxr.202300074) to Advanced Physics Research. </strong></p> <ul> <li><strong>FigX.fig: </strong>Matlab format figure source used to draw all of the plots of the article, embedding the all data.</li> <li><strong>evolution_K.m:</strong> Matlab code file that implement the Repeated Erasure model and compute the success rate of the erasure from the temperature evolution computed from the model.</li> <li><strong>Model_Landauer_enchaine.m:</strong> Matlab code file. Function which uses the SE Model to calculate the evolution of all the energy quantities (average) during step 1 and step 2 starting at an initial temperature CI, and also renders the final temperature conditions to be used iteratively in the RE Model.</li> <li><strong>Toy_Model.m: </strong>Theoretical toy model for explaning the Landauer repeted erasures temperature evolution.</li> <li><strong>Analysis_repeated_erasure.m:</strong> Matlab code file to treat raw data .mat files of 45 repeated erasures to compute the energy, work and heat evolution. The average is done on the full raw data samples corresponding to thousands of 45 repeated erasures.</li> <li><strong>XmsRawData.zip:</strong> Raw data of 45 repeated erasures of duration X ms each. Those Matlab data files are meant to be analysed with the Analysis_repeated_erasure code. Among the usefull variables contained in those files we identifiy :</li> </ul> <ol> <li>V: applied protocol, position of center of the wells in nm</li> <li>x: position signal in nm</li> <li>sigma_m: calibration of the standard deviation used by the feedback</li> <li>x0: threshold of the virtual potential</li> <li>tau1: duration of step1</li> <li>tau2: duration of step 2</li> <li>tau4: half resting time between step1 and step2</li> <li>X1: initial half distance between the wells</li> <li>dt: acquisition sampling time</li> </ol> <p><br> </p> <p> </p>
Data from: The effect of sampling methods on the validity and reliability of the estimation of the orbital stability of human gait
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Data from: N-mixture models estimate abundance reliably: a field test on Marsh Tit using time-for-space substitution
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Data from: Anuran call properties as reliable indicators of environmental suitability for reproduction
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Opening the museum’s vault: Historical field records preserve reliable ecological data
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Data for: Inter-rater reliability of risk of bias tools for non-randomized studies
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Data for: Reliable biogeography requires fossils: Insights from a new species-level phylogeny of extinct and living carnivores
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Data from: Passive acoustic monitoring provides reliable under-estimates of population size and longevity in wild Savannah Sparrows
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Reliable phylogenetic regressions for multivariate comparative data: illustration with the MANOVA and application to the effect of diet on mandible morphology in Phyllostomid bats
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Data from: Reliable and fast genotyping protocol for galactosylceramidase (GALC) in the Twitcher (Twi) mouse
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Data from: Algorithm for post-clustering curation of DNA amplicon data yields reliable biodiversity estimates
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Data from: Strength of female mate preferences in temperature manipulation study supports the signal reliability hypothesis
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Data from: Females can solve the problem of low signal reliability by assessing multiple male traits
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Raw data and outputs from: Sensory trap leads to reliable communication without a shift in nonsexual responses to the model cue
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Data from: Surrogate taxa and fossils as reliable proxies of spatial biodiversity patterns in marine benthic communities
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Data and statistical codes for: Reliability of urological telesurgery compared to local surgery: A multicenter, randomised controlled trial
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Raw data and R code for statistical analyses from: Sensory trap leads to reliable communication without a shift in nonsexual responses to the model cue
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Data from: Assessment of polytraumatized patients according to the Berlin Definition: Does the addition of physiological data really improve interobserver reliability?
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Allen Brain Atlas
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.