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88
datasets available to search
ShareScore release 0.9.0
Dataset results
88 results for “Dictyostelium”
Dictyostelium transcriptional host cell response upon infection with Legionella
GEO Series GSE50680. Dictyostelium discoideum. 27 samples. Type: Expression profiling by array.
Transcription and loop extrusion cooperatively shape the 3D genome of developing slime mold Dictyostelium discoideum [RNA-seq]
GEO Series GSE246367. Dictyostelium discoideum. 8 samples. Type: Expression profiling by high throughput sequencing.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. the L. pneumophila delta DotA mutant 24h p.i.
GEO Series GSE50536. Dictyostelium discoideum. 4 samples. Type: Expression profiling by array.
Functional Characterisation of the Ubiquitin-like Core Autophagy Protein ATG12 in Dictyostelium discoideum
GEO Series GSE123780. Dictyostelium discoideum. 36 samples. Type: Expression profiling by high throughput sequencing.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 3h p.i. (timecourse experiment)
GEO Series GSE50962. Dictyostelium discoideum. 6 samples. Type: Expression profiling by array.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 48h p.i. (timecourse experiment)
GEO Series GSE50965. Dictyostelium discoideum. 6 samples. Type: Expression profiling by array.
MicroRNAs in Amoebozoa: Deep sequencing of the small RNA population in the social amoeba Dictyostelium discoideum reveals developmentally regulated microRNAs
GEO Series GSE38361. Dictyostelium discoideum. 3 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Allorecognition, via TgrB1 and TgrC1, mediates the transition from unicellularity to multicellularity in the social amoebae Dictyostelium discoideum
GEO Series GSE68063. Dictyostelium discoideum. 12 samples. Type: Expression profiling by high throughput sequencing.
The GATA transcription factor gene gtaG is required for terminal differentiation in Dictyostelium.
GEO Series GSE70558. Dictyostelium discoideum. 28 samples. Type: Expression profiling by high throughput sequencing.
The GATA transcription factor GtaC regulates early developmental gene expression dynamics in Dictyostelium
GEO Series GSE63151. Dictyostelium discoideum. 26 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum
GEO Series GSE61914. Dictyostelium discoideum. 67 samples. Type: Expression profiling by high throughput sequencing.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 1h p.i. (timecourse experiment)
GEO Series GSE50963. Dictyostelium discoideum. 6 samples. Type: Expression profiling by array.
Functional Characterisation of the Core Autophagy Protein ATG5 in Dictyostelium discoideum
GEO Series GSE142251. Dictyostelium discoideum. 24 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome profile of Dictyostelium discoideum slugs in clonal and chimeric development
GEO Series GSE118081. Dictyostelium discoideum. 12 samples. Type: Expression profiling by high throughput sequencing.
Global Transcriptional Responses to Cisplatin in Dictyostelium discoideum Identify Potential Drug Targets
GEO Series GSE8287. Dictyostelium discoideum. 100 samples. Type: Expression profiling by array.
CHD chromatin remodelers regulate separate gene sets and distinct stages of Dictyostelium development
GEO Series GSE47222. Dictyostelium discoideum. 8 samples. Type: Expression profiling by high throughput sequencing.
Differential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 6h p.i. (timecourse experiment)
GEO Series GSE50961. Dictyostelium discoideum. 6 samples. Type: Expression profiling by array.
Data from: A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in Dictyostelium
Telomerase, particularly its main subunit, the reverse transcriptase, TERT, prevents DNA erosion during eukaryotic chromosomal replication, but also has poorly understood non-canonical functions. Here, in the model social amoeba Dictyostelium discoideum, we show that the protein encoded by tert has telomerase-like motifs, and regulates, non-canonically, important developmental processes. Expression levels of wild-type (WT) tert were biphasic, peaking at 8 and 12 h post-starvation, aligning with developmental events, such as the initiation of streaming (~7 h) and mound formation (~10 h). In tert KO mutants, however, aggregation was delayed until 16 h. Large, irregular streams formed, then broke up, forming small mounds. The mound-size defect was not induced when a KO mutant of countin (a master size-regulating gene) was treated with TERT inhibitors, but anti-countin antibodies did rescue size in the tert KO. Although, conditioned medium (CM) from countin mutants failed to rescue size in the tert KO, tert KO CM rescued the countin KO phenotype. These and additional observations indicate that TERT acts upstream of smlA/countin: (i) the observed expression levels of smlA and countin, being respectively lower and higher (than WT) in the tert KO; (ii) the levels of known size-regulation intermediates, glucose (low) and adenosine (high), in the tert mutant, and the size defect's rescue by supplemented glucose or the adenosine-antagonist, caffeine; (iii) the induction of the size defect in the WT by tert KO CM and TERT inhibitors. The tert KO's other defects (delayed aggregation, irregular streaming) were associated with changes to cAMP-regulated processes (e.g. chemotaxis, cAMP pulsing) and their regulatory factors (e.g. cAMP; acaA, carA expression). Overexpression of WT tert in the tert KO rescued these defects (and size), and restored a single cAMP signaling centre. Our results indicate that TERT acts in novel, non-canonical and upstream ways, regulating key developmental events in Dictyostelium.
Salmonella infected Dictyostelium discoideum
GEO Series GSE20688. Dictyostelium discoideum. 45 samples. Type: Expression profiling by array.
Role of Epigenetics in Unicellular to Multicellular Transition in Dictyostelium
GEO Series GSE137604. Dictyostelium discoideum; Dictyostelium discoideum AX4. 117 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.