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383 results for “Glioblastoma multiforme”
Mesoporous Silica Nanoparticles for pH-Responsive Delivery of Iridium Metallotherapeutics and Treatment of Glioblastoma Multiforme
<p>Using nanoparticles for controlled drug delivery to cancer, in response to its weakly acidic environment, represents a promising approach toward increasing the effectiveness and reducing the adverse effects of cancer therapy. Hence, the aim of this study is to construct novel mesoporous silica nanoparticle (MSN)-based acidification-responsive drug delivery systems for targeted cancer therapy. Herein, the surface of MSN is covalently functionalized with Ir(III)-based complex through a pH-cleavable hydrazone-based linker and characterized by nitrogen sorption, SEM, FTIR, EDS, TGA, DSC, DLS, and zeta potential measurements. Enhanced release of Ir(III)-complexes is evidenced by UV/VIS spectroscopy at the weakly acidic environments (pH 5 and pH 6) in comparison to the release at physiological conditions. The in vitro toxicity of the prepared materials is tested on healthy MRC-5 cells while their potential for the efficient treatment of glioblastoma multiforme is demonstrated on the U251 cell line.</p>
Radiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma Multiforme
ClinicalTrials.gov study NCT00002545. IPD Sharing: Not stated. Countries: 2. Publications: 4.
Temozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov study NCT00047294. IPD Sharing: Not stated. Countries: 1. Publications: 1.
AZD2171 in Treating Patients With Recurrent Glioblastoma Multiforme
ClinicalTrials.gov study NCT00305656. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov study NCT02853565. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme
ClinicalTrials.gov study NCT00028678. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Verubulin, Radiation Therapy, and Temozolomide to Treat Patients With Newly Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov study NCT01285414. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)
ClinicalTrials.gov study NCT06329570. IPD Sharing: NO. Countries: 1. Publications: 3.
Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov study NCT02685605. IPD Sharing: NO. Countries: 8. Publications: 6.
Computer Planned Radiation Therapy Plus Chemotherapy in Treating Patients With Glioblastoma Multiforme
ClinicalTrials.gov study NCT00003417. IPD Sharing: Not stated. Countries: 2. Publications: 2.
SUTENT (SUNITINIB, SU11248)in Patients With Recurrent or Progressive Glioblastoma Multiforme
ClinicalTrials.gov study NCT00535379. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Short Course vs. Standard Course Radiotherapy in Elderly and/or Frail Patients With Glioblastoma Multiforme
ClinicalTrials.gov study NCT01450449. IPD Sharing: Not stated. Countries: 14. Publications: 6.
Integrative Analysis of Human Glioblastoma Multiforme
ClinicalTrials.gov study NCT03005132. IPD Sharing: YES. Countries: 1. Publications: 1.
Lapatinib With Temozolomide and Regional Radiation Therapy for Patients With Newly-Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov study NCT01591577. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Standard Temodal (Temozolomide) Regimen Versus Standard Regimen Plus Early Postsurgery Temodal for Newly Diagnosed Glioblastoma Multiforme (Study P05572)
ClinicalTrials.gov study NCT00686725. IPD Sharing: YES. Countries: 0. Publications: 1.
Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme
ClinicalTrials.gov study NCT01464177. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Phase II Trial to Assess the Radiosensitizing Effect of ZARNESTRA in Patients With Glioblastoma Multiforme
ClinicalTrials.gov study NCT00209989. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Efficacy & Safety of Autologous Dendritic Cell Vaccination in Glioblastoma Multiforme After Complete Surgical Resection
ClinicalTrials.gov study NCT01006044. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Motexafin Gadolinium Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov study NCT00003409. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
ClinicalTrials.gov study NCT00099125. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.