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54 results for “Hind limb”
Figure 5 in Hind limb myology of the common hippopotamus, Hippopotamus amphibius (Artiodactyla: Hippopotamidae)
Figure 5. Common hippo leg in cranial view.
Data from: Data set incongruence and correlated character evolution: an example of functional convergence in the hind-limbs of stifftail diving ducks
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Data from: A three-dimensional analysis of the morphological evolution and locomotor behaviour of the carnivoran hind limb
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PERMANOVA results from Principal component analysis of avian hind limb and foot morphometrics and the relationship between ecology and phylogeny
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Data from: Phylogenetic variation in hind-limb bone scaling of flightless theropods
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Alternative splicing regulates the physiological adaptation of the mouse hind limb postural and phasic muscles to microgravity
GEO Series GSE178822. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Single cell transcriptomes of developing chicken hind limbs at stages HH25, HH29 and HH31
GEO Series GSE130439. Gallus gallus. 3 samples. Type: Expression profiling by high throughput sequencing.
RNA-Seq analysis of the stage 51 hind limb bud of Xenopus laevis
GEO Series GSE179158. Xenopus laevis. 6 samples. Type: Expression profiling by high throughput sequencing.
Single cell transcriptomes of developing chicken hind limbs at stages HH21, HH24 and HH27
GEO Series GSE174565. Gallus gallus. 3 samples. Type: Expression profiling by high throughput sequencing.
Adult Male Swiss Webster Hind Limb Muscle Satellite Cells
GEO Series GSE14381. Mus musculus. 6 samples. Type: Expression profiling by array.
Doppler images obtained at each scan, for vehicle control vs A-395 treated (i.p. 10 mg/kg) male mice with hind limb ischaemia.
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Comparison of regenerating and non regenerating transgenic stage 52 Xenopus hind limbs
GEO Series GSE9813. Xenopus laevis. 4 samples. Type: Expression profiling by array.
Alternative splicing regulates the physiological adaptation of the mouse hind limb postural and phasic muscles to microgravity
We sought to comprehensively elucidate the transcriptomic underpinnings of microgravity-induced muscle phenotypes in mice by evaluating both differential gene expression (DGE) and changes in alternative splicing (AS) due to extended spaceflight. Total RNA was isolated from the gastrocnemius and quadriceps, postural and phasic muscles of the hind limb, respectively, of 32-week-old female BALB/c mice exposed to microgravity or ground control conditions for nine weeks. RNA sequencing revealed that DGE and AS varied across postural and phasic muscle types with preferential employment of DGE in the gastrocnemius and AS in the quadriceps. Gene ontology analysis indicated that DGE and AS regulate distinct molecular processes. Various non-differentially expressed transcripts encoding musculoskeletal proteins (Tnnt3, Tnnt1, Neb, Ryr1, and Ttn) and muscle-specific RNA binding splicing regulators (Mbnl1 and Rbfox1) were found to have significant changes in AS that altered critical functional domains of their protein products. In striking contrast, microgravity-induced differentially expressed genes were associated with translation/ribosomal function and lipid metabolism. Our work serves as the first comprehensive investigation of coordinate changes in DGE and AS in large limb muscles across spaceflight. We propose that substantial remodeling of pre-mRNA by AS is a major component of transcriptomic adaptation of skeletal muscle to microgravity. The alternatively spliced genes identified here could be targeted by small molecule splicing regulator therapies to address microgravity-induced changes in muscle during spaceflight.
Expression data during plantaris muscle regrowth following two weeks of hind limb suspension in young adult mice
GEO Series GSE56798. Mus musculus. 7 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.