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ShareScore release 0.9.0
Dataset results
87 results for “Hydra”
Data from: Comprehensive machine learning analysis of Hydra behavior reveals a stable basal behavioral repertoire
Open the record for dataset details and reuse information.
Data from: Stem cell differentiation trajectories in Hydra resolved at single-cell resolution
Open the record for dataset details and reuse information.
HydRA: Deep-learning models for predicting RNA-binding capacity from protein interaction association context and protein sequence
GEO Series GSE221870. Homo sapiens. 76 samples. Type: Other.
H4K20me1 plays a dual role in transcriptional regulation during regeneration and axis patterning of Hydra [RNA-seq]
GEO Series GSE205916. Hydra vulgaris. 30 samples. Type: Expression profiling by high throughput sequencing.
Integrative analysis of Hydra head regeneration reveals activation of distal enhancer-like elements [RNA-seq]
GEO Series GSE127279. Hydra vulgaris. 40 samples. Type: Expression profiling by high throughput sequencing.
Analysis of gene expression in MyD88-Knockdown-Hydra vulgaris (AEP)
GEO Series GSE32383. Hydra vulgaris. 11 samples. Type: Expression profiling by array.
Extracellular vesicles mediate molecular signalling during Hydra regeneration
GEO Series GSE180886. Hydra vulgaris. 2 samples. Type: Expression profiling by high throughput sequencing.
The transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra.
GEO Series GSE190110. Hydra vulgaris. 15 samples. Type: Expression profiling by high throughput sequencing.
The transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra
GEO Series GSE191177. Hydra vulgaris. 36 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide maps RNA Polymerase II and Histone H3 of Hydra vulgaris
GEO Series GSE63414. Hydra vulgaris. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Naturally occurring tumours in the basal metazoan Hydra.
GEO Series GSE56287. Hydra oligactis. 13 samples. Type: Expression profiling by array.
H4K20me1 plays a dual role in transcriptional regulation during regeneration and axis patterning of Hydra
GEO Series GSE205918. Hydra vulgaris. 51 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Identification of genes involved in symbiosis of green hydra and Chlorella
GEO Series GSE97633. Hydra viridissima. 12 samples. Type: Expression profiling by array.
A tHeranostic approach to reduce local recurrence of MYxofibrosaRcomA (HYdRA)
<p>Photodynamic therapy (PDT) is an approved cancer treatment worldwide that uses targeted, harmless red light to activate non-toxic photosensitizers. This innovative and minimally invasive method induces cytotoxic effects in diseased areas by promoting the production of reactive oxygen species while preserving healthy tissues. Despite advancements in surgical practices, achieving complete microscopic resection remains challenging, often leading to local relapse. Therefore, combining fluorescence-guided microsurgery (FGMS) with PDT could be a promising strategy to eradicate resectable tumors with a high risk of recurrence.</p> <p>This project aims to provide preclinical proof of the applicability of FGMS coupled with PDT in treating Myxofibrosarcoma (MFS) and Osteosarcoma (OS), the main representative subtypes of soft tissues and bone sarcomas, prone to relapse after surgery. We tested a panel of photosensitizers (PSs) that can be photoactivated with light in the 630-660 nm wavelengths’ range in <em>in vitro</em> 2D and 3D models of MFS and OS cell lines, along with <em>ex-vivo</em> patient-derived samples and <em>in vivo</em> xenograft zebrafish embryos. The PSs were ranked on (a) selective uptake by tumor cells, compared to healthy cells and (b) the cytotoxic effect, after irradiation. </p> <p>Hence, these results provide a preclinical proof of concept for a novel therapeutic approach that effectively could eradicate MFS and OS inducing cytotoxic effects in cancer cells while preserving healthy tissue. This approach could reduce cancer recurrence and pave the way for extending this strategy to other pathologies.</p>
Hydra Single-centre Experience - Copenhagen, Denmark
ClinicalTrials.gov study NCT06342635. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Hydra Registry - UK
ClinicalTrials.gov study NCT06507579. IPD Sharing: NO. Countries: 1. Publications: 0.
HYpofractionateD RadioAblative (HYDRA) Treatment of Advanced Laryngeal Cancer
ClinicalTrials.gov study NCT02464137. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Hydra Registry - Italy Experience
ClinicalTrials.gov study NCT05956652. IPD Sharing: NO. Countries: 1. Publications: 0.
Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer
ClinicalTrials.gov study NCT03114462. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Hydroxychloroquine Treatment for Severe COVID-19 Pulmonary Infection (HYDRA Trial)
ClinicalTrials.gov study NCT04315896. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.