Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
547
datasets available to search
ShareScore release 0.9.0
Dataset results
547 results for “Infection Control”
Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 703/HPTN 081 AMP Study
ClinicalTrials.gov study NCT04860323. IPD Sharing: Not stated. Countries: 4. Publications: 1.
Disease hotspots or hot species? Infection dynamics in multi-host metacommunities controlled by species identity, not source location
Open the record for dataset details and reuse information.
Data from: Host control by Acmispon strigosus constrains fitness gains of ineffective Bradyrhizobium symbionts in mixed infections
Open the record for dataset details and reuse information.
Data from: Estimating transmission dynamics and serial interval of the first wave of COVID-19 infections under different control measures: A statistical analysis in Tunisia from February 29 to May 5, 2020
Open the record for dataset details and reuse information.
A randomized clinical trial to compare P. falciparum gametocytaemia and infectivity following blood-stage or mosquito bite induced controlled malaria infection
Open the record for dataset details and reuse information.
Data from: Inter- and intra-specific variation of spider mite susceptibility to fungal infections: implications for the long-term success of biological control
<p><span><span><span><span><span><span><span><span><span><span><span>Spider mites are severe pests of several annual and perennial crops worldwide, often causing important economic damages. As rapid evolution of pesticide resistance in this group hampers the efficiency of chemical control, alternative control strategies, such as the use of entomopathogenic fungi, are being developed. However, while several studies have focused on the evaluation of the control potential of different fungal species and/or isolates as well as their compatibility with other control methods (e.g. predators or chemical pesticides), knowledge on the extent of inter- and intraspecific variation in spider mite susceptibility to fungal infection is as yet incipient. Here, we measured the mortality induced by two generalist fungi, <i>Beauveria </i><i>bassiana </i>and <i>Metarhizium </i><i>brunneum</i>, in 12 spider mite populations belonging to different <i>Tetranychus </i>species: <i>T. evansi</i>, <i>T. ludeni</i>, the green form of <i>T. urticae </i>and the red form of <i>T. urticae</i>, within a full factorial experiment. We found that spider mite species differed in their susceptibility to infection by both fungal species. Moreover, we also found important intraspecific variation for this trait. These results draw caution on the development of single strains as biocontrol agents. Indeed, the high level of intraspecific variation suggests that (a) the one-size-fits-all strategy may fail to control spider-mite populations and (b) hosts resistance to infection may evolve at a rapid pace. Finally, we propose future directions to better understand this system and improve the long-term success of spider mite control strategies based on entomopathogenic fungi.</span></span></span></span></span></span></span></span></span></span></span></p>
Schizophrenia and Bartonella spp. infection: A pilot case–control study
<p>Recently, infections with emerging zoonotic bacteria of the genus Bartonella have been reported in association with a range of CNS symptoms. Currently, it remains unknown if Bartonella spp. infection is associated with symptoms of schizophrenia/schizoaffective disorder (SCZ/SAD). The objective of this study was to determine if there is an association between Bartonella species infection and SCZ/SAD. A secondary objective was to determine if SCZ/SAD symptoms were more severe among participants with documented Bartonella spp. infection. Using a case–control study design, 17 cases and 13 controls were evaluated with a series of clinical and cognitive assessments. Blood samples were collected and tested for Bartonella spp. infection using serological, microbiological, and molecular techniques. People with SCZ/SAD were more likely than healthy volunteers to have Bartonella spp. DNA in their bloodstream, with 11 of 17 cases (65%) positive by Bartonella spp. droplet digital PCR (ddPCR). In comparison, only one healthy volunteer was Bartonella spp. ddPCR positive (8%, p = 0.0024). Based on serology, Bartonella spp. exposure was common among people with SCZ/SAD (12 of 17) as well as among healthy volunteers (12 of 13), with no significant difference between the groups ( p = 0.196). Within the case group of people with SCZ/SAD, there was no significant difference in SCZ/SAD severity scores between people with and without ddPCR evidence of Bartonella spp. infection. This pilot study provides preliminary evidence in support of future investigations that should examine a potential contribution of Bartonella spp. infection to SCZ/SAD.</p>
Dataset for "Glycaemic control is associated with SARS-CoV-2 breakthrough infections in vaccinated patients with Type 2 diabetes"
<p>Dataset for "Glycaemic control is associated with SARS-CoV-2 breakthrough infections in vaccinated patients with Type 2 diabetes"</p>
Figure 2 in Placebo-Controlled Phase 3 Trial of a Recombinant Glycoprotein 120 Vaccine to Prevent HIV-1 Infection
Figure 2. Self-reported risk behaviors by treatment arm and month of visit. STDs, sexually transmitted diseases.
Characterizing diffusion-controlled release of small-molecules using quantitative MRI: Application to orthopedic infection - dataset
<p>Dataset for paper submitted to Scientific Reports titled "Characterizing diffusion-controlled release of small-molecules using quantitative MRI: Application to orthopedic infection"</p>
IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic Trypanosoma brucei infection
<p>In the skin, <em>Trypanosoma brucei </em>colonises the subcutaneous white adipose tissue (WAT) and harbours a pool of parasites competent for forward transmission. The interaction between parasites, adipose tissue, and the local immune system is likely to drive adipose tissue wasting and weight loss observed in cattle and humans infected with <em>T. brucei</em>. However, mechanistically, this process is not fully understood. Here, using several complementary approaches including mass cytometry by time of flight, bulk and single cell transcriptomics, we found that <em>T. brucei</em> infection drives a local expansion of several IL-17A-producing cells in the murine WAT, including T<sub>H</sub>17 and Vg6<sup>+</sup> T cells. We also found that global IL-17 deficiency, or mice lacking IL-17 receptor expression specifically on adipocytes, were protected from infection-induced WAT wasting and weight loss. Unexpectedly, we found that abrogation of IL-17 signalling on adipocytes results in higher burden of extravascular parasites in the WAT. Taken together, our study highlights the central role of IL-17 signalling on adipocytes in controlling WAT responses to infection, suggesting that adipocytes are a critical coordinator of the tissue immune response to <em>T. brucei</em> infection. </p>
Underlying dataset for the manuscript titled "Identification of RTS,S/AS01 vaccine-induced humoral biomarkers predictive of protection against controlled human malaria infection"
<p><span>The antibody binding data included in this dataset is associated with the manuscript “Spreng, R.L., Seaton, K.E. et al., <em><span>Identification of RTS,S/AS01 vaccine-induced humoral biomarkers predictive of protection against controlled human malaria infection; </span></em><span>Accepted for Publication in JCI Insight (2024)</span>. These data come from the characterization of serum samples from four controlled human malaria infection (CHMI) clinical trials of the RTS,S vaccine, including NCT01366534 (referred to as MAL068), NCT01857869 (referred to as MAL071), NCT03162614 (referred to as MAL092), and NCT03824236 (referred to as MAL102).</span></p>
Establishing a Controlled Human Hookworm Infection Model at Leiden University Medical Center
ClinicalTrials.gov study NCT03126552. IPD Sharing: NO. Countries: 1. Publications: 1.
A Strep Throat Controlled Human Infection Trial in Healthy Adults
ClinicalTrials.gov study NCT06992141. IPD Sharing: YES. Countries: 1. Publications: 1.
Infection Control Link Nurses Program to Improve Compliance With Standard Precautions, Hand Hygiene, and Prevent Healthcare-Associated Infections
ClinicalTrials.gov study NCT06857825. IPD Sharing: NO. Countries: 1. Publications: 13.
Effect of Intensive Fly Control on Trachoma and Ocular Chlamydia Infection in Tanzania
ClinicalTrials.gov study NCT00347763. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Evaluation of the Protective Efficacy of TV003 or Previous Zika Infection Against Infection With ZIKV-SJRP Challenge Compared to DENV and ZIKV-naïve Controls Against Infection With ZIKV-SJRP Challenge
ClinicalTrials.gov study NCT06805487. IPD Sharing: NO. Countries: 1. Publications: 3.
Treatment With MSC in HIV-infected Patients With Controlled Viremia and Immunological Discordant Response
ClinicalTrials.gov study NCT02290041. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adults: Heterologous vs. Homologous Controlled Human Malaria Infection and Reduction in Number
ClinicalTrials.gov study NCT02215707. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Comparison of Three Plasmodium Falciparum Isolates in a Controlled Human Malaria Infection
ClinicalTrials.gov study NCT01627951. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.