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261 results for “Interruption”
Data from: Reduction in arterial stiffness and vascular age by naltrexone-induced interruption of opiate agonism
Objective: To prospectively assess if opiate antagonist treatment or the opiate-free status could reverse opiate-related vasculopathy. Design: Longitudinal Open Observational, Serial "N of One", over 6.5 years under various treatment conditions: opiate dependence, naltrexone and opiate-free. Setting: Primary care, Australia. Participants: 20 opiate dependent patients (16 males: 16 cases of buprenorphine 4.11+1.17mg, two of methadone 57.5+12.5mg and two of heroin 0.75+0.25g). Intervention: Studies of Central Arterial Stiffness and vascular reference age (RA) were performed longitudinally by SphygmoCor Pulse Wave Analysis (AtCor, Sydney). Primary Outcomes: Primary outcome was vascular age and arterial stiffness accrual under different treatment conditions. Results: The mean chronological age (CA) was 33.62+2.03 years. The opiate-free condition was associated with a lower apparent vascular age both in itself (males: P=0.0402, females: P=0.0360) and in interaction with time (males: P=0.0001; females: P=0.0004), and confirmed with other measures of arterial stiffness. The mean modelled RA was 38.82, 37.73 and 35.05 years in the opiate, naltrexone and opiate-free conditions respectively. The opiate-free condition was superior to opiate agonism after full multivariate adjustment (P=0.0131), with modelled RA/CA of 1.0173, 0.9563, and 0.8985 (reductions of 6.1% and 11.9% respectively). Conclusions: Data demonstrate that opiate-free status improves vascular age and arterial stiffness in previous chronic opiate users.. The role of opiate antagonist treatment in achieving these outcomes requires future clarification and offers hope of novel therapeutic remediation.
Raw data for the article "Interrupted Polonovski strategy for the synthesis of functionalized amino acids and peptides"
<p>Raw NMR, IR, and MS data for the article "Interrupted Polonovski strategy for the synthesis of functionalized amino acids and peptides" published in Organic Letters, DOI: </p> <p><a title="DOI URL" href="https://doi.org/10.1021/acs.orglett.3c03603">https://doi.org/10.1021/acs.orglett.3c03603</a></p> <p>The number of the folders either correspond to compounds numbers in the article or the name of the folder is self-describing. All details concerning conditions and equipment for measurements can be found in the supporting information of the article. For convenience, the word file version of the supporting information can be found on the top of the raw data folder.</p>
Data set for energy landscapes for interrupted sequences
<p>Databases of minima and transition states produced with PATHSAMPLE for interrupted tropocollagen segments.</p> <p>The two databases are for a GPO and a GPP repeat model (7 repeats per chain, with ACE and NME caps).</p> <p>One strand contains a deletion of the form GPO-GP-GPO and GPP-GP-GPP.</p>
Supporting data for "Rapid determination of solid-state diffusion coefficients in Li-based batteries via intermittent current interruption method"
<p>This is the dataset of electrochemical and operando X-ray diffraction experiments for our publication "Rapid determination of solid-state diffusion coefficients in Li-based batteries via intermittent current interruption method". This archive contains the raw data and scripts written in R used in the analysis and presentation of the results in this manuscript.</p> <p><strong>Abstract of the manuscript:</strong></p> <p>The galvanostatic intermittent titration technique (GITT) is considered the go-to method for determining the Li<sup>+</sup>diffusion coefficients in insertion electrode materials. However, GITT-based methods are either time-consuming, prone to analysis pitfalls or require sophisticated interpretation models. Here, we propose the intermittent current interruption (ICI) method as a reliable, accurate and faster alternative to GITT-based methods. Using Fick’s laws, we prove that the ICI method renders the same information as the GITT within a certain duration of time since the current interruption. Via experimental measurements, we also demonstrate that the results from ICI and GITT methods match where the assumption of semi-infinite diffusion applies. Moreover, the benefit of the non-disruptive ICI method to operando materials characterization is exhibited by correlating the continuously monitored diffusion coefficient of Li<sup>+</sup> in a LiNi<sub>0.8</sub>Mn<sub>0.1</sub>Co<sub>0.1</sub>O<sub>2</sub>-based electrode to its structural changes captured by operando X-ray diffraction measurements.</p>
Five-Drug Anti-HIV Treatment Followed by Treatment Interruption in Patients Who Have Recently Been Infected With HIV
ClinicalTrials.gov study NCT00000940. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Microcomplications in Lap. Cholecystectomy: Reducing Intraoperative Interruptions by High Resolution Standardization
ClinicalTrials.gov study NCT03329859. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Procalcitonin in Early Antibiotic Interruption in Patient With Bacterial Pulmonary infeCtion and Acute Heart Failure
ClinicalTrials.gov study NCT02787603. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Sequence of Vessel Interruption and Circulating Tumor Cells in Surgical Lung Cancer
ClinicalTrials.gov study NCT03645252. IPD Sharing: NO. Countries: 1. Publications: 2.
Interrupting Self-Harm Study
ClinicalTrials.gov study NCT03550521. IPD Sharing: NO. Countries: 1. Publications: 1.
Reference Values for Respiratory Resistance Measured by the Interrupter Technique in Adults
ClinicalTrials.gov study NCT00213850. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Immune and Viral Outcomes of HIV-1 Therapy Interruption
ClinicalTrials.gov study NCT00051818. IPD Sharing: Not stated. Countries: 1. Publications: 4.
An Antiretroviral Treatment Interruption (ATI) Study to Evaluate the Impact of Genetically Modified Autologous Cells (AGT103-T) to Suppress Human Immunodeficiency Virus Replication in the Absence of A
ClinicalTrials.gov study NCT05540964. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Double Randomization of a Monitoring Adjusted Antiplatelet Treatment Versus a Common Antiplatelet Treatment for DES Implantation, and Interruption Versus Continuation of Double Antiplatelet Therapy
ClinicalTrials.gov study NCT00827411. IPD Sharing: Not stated. Countries: 1. Publications: 6.
SCOPE Analytic Treatment Interruption Protocol
ClinicalTrials.gov study NCT04359186. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study for Testing Text Messaging and Newsletter as a Strategy for Interrupting Sedentary Behavior
ClinicalTrials.gov study NCT03671499. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Randomised Trial of Structured Treatment Interruption of HAART in HIV-Infected Adults in Abidjan (ANRS 1269 TRIVACAN)
ClinicalTrials.gov study NCT00158405. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Prospective Multicentric Randomized Study of Glivec® in Advanced GIST Expressing C-kit: Interruption After 5 Years vs Maintenance
ClinicalTrials.gov study NCT00367861. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Periprocedural Continuation Versus Interruption of Oral Anticoagulant Drugs During Transcatheter Aortic Valve Implantation (POPular PAUSE TAVI)
ClinicalTrials.gov study NCT04437303. IPD Sharing: Not stated. Countries: 6. Publications: 2.
Daily Sedative Interruption in Critically Ill Patients Being Managed With a Sedation Protocol
ClinicalTrials.gov study NCT00298493. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Immune Response to a Therapeutic HIV Vaccine Followed by Treatment Interruption in Patients With Acute or Recent HIV Infection
ClinicalTrials.gov study NCT00183261. IPD Sharing: Not stated. Countries: 3. Publications: 4.
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