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ShareScore release 0.9.0
Dataset results
43 results for “Leukoencephalopathy”
Retrospective Study of the Survival of Patients Suffering From Hiv-related Progressive Multifocal Leukoencephalopathy
ClinicalTrials.gov study NCT02895581. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Adoptive Transfer of JC Virus-Specific T Lymphocytes for the Treatment of Progressive Multifocal Leukoencephalopathy
<p>The dataset reports the clinical and paraclinical characteristics of the 9 patients treated with T cell therapy included in the final article, including gender, age at diagnosis, underlying hematological conditions, neurological symptoms at diagnosis, JCV viral load in the cerebrospinal fluid, number of T cell infusions, and neurological outcome following treatment. Nuclear magnetic resonance data are not reported.</p> <p>The aim of this study was to analyze the safety and carry out preliminary evaluation of the efficacy of polyomavirus JC (JCPyV) -specific T cell therapy in a cohort of hematological patients with PML.</p> <p>9 patients with a diagnosis of "definite PML" who were showing progressive clinical deterioration received JCPyV-specific T cells. Cell lines were expanded from autologous or allogenic peripheral blood mononuclear cells by stimulation with JCPyV antigen-derived peptides.</p> <p>In the evaluable patients, an increase in the frequency of circulating JCPyV-specific lymphocytes was observed, with a decrease or clearance of JCPyV viral load in cerebrospinal fluid. In responsive patients, transient appearance of punctate areas of contrast enhancement within, or close to, PML lesions was observed, which was interpreted as a sign of immune control and which regressed spontaneously without the need for steroid treatment. Six of 9 patients achieved PML control, with 5 alive and in good clinical condition at their last follow-up. None of the patients experienced treatment-related adverse events.</p>
Datset relate to article "3-METHYLGLUTACONIC ACIDURIA TYPE I: A RARE CAUSE OF LATE-ONSET LEUKOENCEPHALOPATHY"
<p><strong>gene panel data of AUH case</strong></p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.