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141
datasets available to search
ShareScore release 0.9.0
Dataset results
141 results for “Microtubules”
ATG9A regulates dissociation of recycling endosomes from microtubules leading to formation of influenza A virus liquid condensates - MAIN FIGURES
<p>Metadata for the manuscript entitled "ATG9A regulates dissociation of recycling endosomes from microtubules leading to formation of influenza A virus liquid inclusions" - MAIN FIGURES</p>
Data supplement for "Molecular motors enhance microtubule lattice plasticity" Lecompte, William; John, Karin
<p>This dataset contains the data and source files for figures 2 (a-e), 3(a-d), 4(b,c,e) and Supplementary figures 5, 7(a-e), 8 and 9(a-c) in the following publication: </p> <p> </p> <p>W. Lecompte and K. John</p> <p> </p> <p>"Molecular motors enhance microtubule lattice plasticity"</p> <p> </p> <p>published in 2023 in PRX Life (ArXiv https://arxiv.org/abs/2209.09161)</p> <p> </p> <p>Please follow the instructions given in 'Readme.txt'.</p> <p> </p>
RNA-seq and label-free quantitative proteomics data from: KDM4A serves as an α-tubulin demethylase regulating microtubule polymerization and cell mitosis
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Data from: Mechanical fatigue in microtubules
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Data for: Doublecortin reinforces microtubules to promote growth cone advance in soft environments
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Microtubule networks in zebrafish hair cells facilitate presynapse transport and fusion during development
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The non-mitotic role of HMMR in regulating the localization of TPX2 and the dynamics of microtubules in neurons
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Data for: The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC)
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Data from: O-GlcNAc modification differentially regulates microtubule binding and pathological conformations of tau isoforms in vitro
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Vimentin supports cell polarization by enhancing centrosome function and microtubule acetylation
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Supplementary videos for "Interplay Between Convective and Viscoelastic Forces Controls the Morphology of in vitro Paclitaxel- Stabilized Microtubules"
<p>Supplementary videos for MDPI Crystals manuscript "Interplay Between Convective and Viscoelastic Forces Controls the Morphology of in <em>vitro</em> Paclitaxel- Stabilized Microtubules "</p>
Cellulose Synthase Tethering Attenuates Mechano-induced Microtubule Organization in pavement cells
<p>Mechanical forces control development in plants and animals, acting as cues in pattern formation and as the driving force of morphogenesis. In mammalian cells, molecular assemblies residing at the interface of the cell membrane and the extracellular matrix play an important role in perceiving and transmitting external mechanical signals to trigger physiological responses. Similar processes occur in plants, but there is little understanding of the molecular mechanisms and their genetic basis. Here, we show that number and movements directions of cellulose synthase complexes (CSCs) at the plasma membrane vary during initial stages of development in the cotyledon epidermis of Arabidopsis, closely mirroring the microtubule organization. Uncoupling microtubules and CSCs resulted in enhanced microtubule co-alignment as caused by mechanical stimuli driven either by cell shape or by tissue-scale physical perturbations. Furthermore, micromechanical perturbation resulted in depletion of CSCs from the plasma membrane suggesting a possible link between cellulose synthase removal from the plasma membrane and microtubule response to mechanical stimuli. Taken together, our results suggest that the interaction of cellulose synthase and cortical microtubules forms a physical continuum between the cell wall, plasma membrane, and the cytoskeleton that modulates the mechano-response of the cytoskeleton.</p>
Data for "Estimation of microtubule-generated forces using a DNA origami nanospring"
<p>Data in support of the publication "Estimation of microtubule-generated forces using a DNA origami nanospring"</p>
Microtubule edge detector training dataset
<p>Training data for training models for doing segmentation of edges of the Kymographs obtained by using the Multi Kymograph tool of Fiji. The images were acquired at the Kyushu university by Professor Daisuke INOUE and annotation of the data and training of the segmentation model was done by Varun Kapoor at Kapoorlabs in Paris.</p>
Pylake example: Kinesin stepping on a microtubule
<p>Kinesin stepping on a microtubule</p>
Electron tomography of mouse LINC complexes at meiotic telomere attachment sites with and without microtubules - High Resolution Supplementary Movies
<p>High resolution movies of the paper 'Electron tomography of mouse LINC complexes at meiotic telomere attachment sites with and without microtubules' by Spindler et al..</p> <p><strong>Supplementary Movie 1:</strong> Transmission electron tomographic reconstruction and annotation of a meiotic telomere attachment site to the nuclear envelope (NE). The movie sequence shows the progression through the tomogram in z with annotations on individual virtual sections. The combination of virtual sections results in the 3D model of the site. After an initial rotation of the model, the nuclear envelope is faded out to provide better visibility of the filaments. Annotations include the synaptonemal complex (lateral elements in magenta, central element in yellow), attachment plates (lilac) the transverse filaments (blue) and the LINC complexes (light cyan).</p> <p><strong>Supplementary Movie 2:</strong> Transmission electron tomographic reconstruction and annotation of a meiotic telomere attachment site to the nuclear envelope (NE) with a microtubule. Movie sequence progresses through the reconstructed tomogram, showing how the annotation of the structures of interest on individual virtual sections combine into a 3D model of the attachment site. The attachment site is close to a microtubule running parallel to the nuclear envelope. Annotations in accordance with Supplementary Movie 1, microtubule annotated in purple.</p> <p> </p>
Mass spectrometry of natively decorated doublet microtubule from Tetrahymena thermophila WT and mutants
<p>Cilia are thin microtubule-based protrusions of eukaryotic cells. The swimming of ciliated protists and sperm cells is propelled by the beating of cilia. Cilia propagate the flow of mucus in the trachea and protect the human body from viral infections. The main force generators of ciliary beating are the outer dynein arms (ODAs) which attach to the doublet microtubules. The bending of cilia is driven by the ODAs' conformational changes caused by ATP hydrolysis. Here, we report the native ODA complex structure attaching to the doublet microtubule by cryo-electron microscopy and mass spectrometry. The structure reveals how the ODA complex is attached to the doublet microtubule via the docking complex in its native state. Combined with coarse-grained molecular dynamics simulations, we present a model of how the attachment of the ODA to the doublet microtubule induces remodeling and activation of the ODA complex.</p>
Preference of CAMSAP3 for expanded microtubule lattice contributes to stabilization of the minus end
<p>Dataset for the publication.</p> <p>biorxiv: https://www.biorxiv.org/content/10.1101/2022.08.21.504720v1</p>
Pharmacodynamic Biomarkers of Standard Anti-microtubule Drugs as Assessed by Early Tumor Biopsy
ClinicalTrials.gov study NCT03393741. IPD Sharing: NO. Countries: 1. Publications: 1.
Data from: Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.