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ShareScore release 0.9.0
Dataset results
82 results for “Mouse Imaging”
Synchrotron CT image of hyaline cartilage lesion in the tibia of a 9 week old male STR/Ort mouse
<p>Figure from: Evans, L. A. E. (2023). <em>Imaging the articular osteochondral interface. </em>PhD Thesis. Royal Veterinary College, University of London, UK.</p> <p>Video of synchrotron CT slices showing hyaline cartilage lesion in the tibia of a 9 week old male STR/Ort mouse. Image obtained on the I13-2 beamline at Diamond Light Source, Oxfordshire, during beamtime MG24786-2. Scanning involved a bespoke cold stage designed by researchers including Dr Peter Rockett, Dr Saurabh Shah and Professor Peter Lee. Cold stage details can be found in a published research article with DOI: 10.1039/c7ra00642j. </p>
Phenotype images of the developing heart from wild type and Sox7 mutant mouse embryo
<p><span>The cardiac endothelium influences ventricular chamber development by coordinating trabeculation and compaction. However, the endothelial-specific molecular mechanisms mediating this coordination are not fully understood</span>. Here, we identified the Sox7 transcription factor as a critical cue instructing cardiac endothelium identity during ventricular chamber development. E<span>ndothelial-specific loss of <em>Sox7</em> function in mice results in cardiac ventricular defects similar to non-compaction cardiomyopathy, with a change in the proportions of trabecular and compact cardiomyocytes in the mutant hearts. This phenotype is paralleled by abnormal coronary artery formation. Loss of Sox7 function disrupts the transcriptional regulation of the Notch pathway and connexins 37 and 40, which govern coronary arterial specification. Upon Sox7 endothelial-specific deletion, single-nuclei transcriptomics analysis identified the depletion of a subset of Sox9/Gpc3 positive endocardial progenitor cells and an increase in erythro-myeloid cell lineages. Fate mapping analysis revealed that a subset of Sox7-null endothelial cells transdifferentiate into hematopoietic but not cardiomyocyte lineages. Our findings determine that Sox7 maintains cardiac endothelial cell identity, which is crucial to the cellular cross-talk that drives ventricular compaction and coronary artery development.</span></p>
maDLC Tri-Mouse Benchmark Dataset - Test Images
<p>see https://benchmark.deeplabcut.org/ for more information.</p>
Microscopy images of the effects of PDZ-RhoGEF manipulation on dendritic spines and videos of effects on PDZ-RhoGEF on mouse behavioral phenotypes
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Code and imaging data for: Mouse epidermal chromatin architecture
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Data from: Deuterium metabolic imaging phenotypes mouse glioblastoma heterogeneity through glucose turnover kinetics
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Imaging the onset of oscillatory signaling dynamics during mouse embryo gastrulation
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CODEX multiplexed imaging of immunotherapy in human and mouse melanomas
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A selective small-molecule agonist of G protein-gated inwardly-rectifying potassium channels reduces epileptiform activity in a mouse model of tumor associated epilepsy - Part 3: Thy1-GCaMP Tumor Imaging EXCERPT
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4D light sheet imaging, computational reconstruction, and cell tracking in mouse embryos -- example data (raw .czi and fused .klb light sheet images of mouse E7.5)
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Phenotype images of the developing heart from wild type and Sox7 mutant mouse embryo
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Microscopy images from: A physiological and histological atlas of reproduction in the North American deer mouse (Peromyscus maniculatus)
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Single cell data from Imaging Mass Cytometry of mouse lung tumours treated with KRAS-G12C and immune checkpoint inhibitors (Dataset 3)
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Implantation of abdominal imaging windows on the mouse liver - short version
<p>This video describes the surgical process of implanting an abdominal imaging window (AIW) on the liver of mice. This window can be used for acute or longitudinal imaging. All experiments have been reviewed and approved by the local authorities (Landesdirektion Sachsen).</p> <p>Implantation of chronic abdominal windows allows for microscopical investigation of highly dynamic processes in physiological and pathological circumstances and is generally tolerated well by experimental animals. It enables insights which otherwise could only be obtained using high numbers of experimental animals. The method can be regarded as reduction approach in terms of 3R implementation.</p> <p>This upload contains the short version and is distributed under CC BY-ND 4.0 license to inhibit decontextualized misuse. Please check license terms for usage, especially for remixing/transforming! If you want to remix the material, get in contact with the author.</p>
Implantation of abdominal imaging windows on the mouse liver
<p>This video describes the surgical process of implanting an abdominal imaging window (AIW) on the liver of mice. This window can be used for acute or longitudinal imaging. All experiments have been reviewed and approved by the local authorities (Landesdirektion Sachsen).</p> <p>Implantation of chronic abdominal windows allows for microscopical investigation of highly dynamic processes in physiological and pathological circumstances and is generally tolerated well by experimental animals. It enables insights which otherwise could only be obtained using high numbers of experimental animals. The method can be regarded as reduction approach in terms of 3R implementation.</p> <p>This upload contains the full version and is distributed under CC BY-ND 4.0 license to inhibit decontextualized misuse. Please check license terms for usage, especially for remixing/transforming! If you want to remix the material, get in contact with the author.</p>
Implantation of abdominal imaging windows on the mouse kidney - short version
<p>This video describes the surgical process of implanting an abdominal imaging window (AIW) on the kidney of mice. This window can be used for acute or longitudinal imaging. All experiments have been reviewed and approved by the local authorities (Landesdirektion Sachsen).</p> <p>Implantation of chronic abdominal windows allows for microscopical investigation of highly dynamic processes in physiological and pathological circumstances and is generally tolerated well by experimental animals. It enables insights which otherwise could only be obtained using high numbers of experimental animals. The method can be regarded as reduction approach in terms of 3R implementation.</p> <p>This upload contains the shortened version and is distributed under CC BY-ND 4.0 license to inhibit decontextualized misuse. Please check license terms for usage, especially for remixing/transforming! If you want to remix the material, get in contact with the author.</p>
Dataset supporting the paper "Characterization of a mouse-sized receive-only coil for a preclinical magnetic particle imaging scanner"
<p>We have recently submitted a paper on the characterization of a mouse-sized receive-only coil for the Bruker preclinical MPI scanner. This dataset contains the measurements for our comparison between the native transmit-receive (TxRx) coil of the scanner and the new mouse-sized receive-only (Rx) coil. </p> <p>Included are: </p> <ul> <li>Network analyzer (NA) measurements as csv, first column=frequency, second column=power transfer. There are measurements at the center of the coils and along x- and y-axis with a 2mm step size.</li> <li>System matrix (SM) measurements, including the background (BG) measurements and the calculated particle signal-to-noise ratio (SNR) (Bruker file format).</li> <li>MPI measurements of a dilution series (Bruker file format). In the dilution series folders there is a readme, which sample "#A" was measured at which position "_A"/"_B"/"_C", is saved in which folder "(E#)" and contains which iron amount (in ng). </li> </ul>
Mouse (noise 0) dataset for microscopy image denoising and segmentation benchmark as used in DenoiSeg paper (https://arxiv.org/abs/2005.02987)
<p>Mouse n0 dataset for microscopy image denoising and segmentation benchmark as used in DenoiSeg paper (https://arxiv.org/abs/2005.02987)</p>
Mouse (noise 10) dataset for microscopy image denoising and segmentation benchmark as used in DenoiSeg paper (https://arxiv.org/abs/2005.02987)
<p>Mouse n10 dataset for microscopy image denoising and segmentation benchmark as used in DenoiSeg paper (https://arxiv.org/abs/2005.02987)</p>
Mouse (noise 20) dataset for microscopy image denoising and segmentation benchmark as used in DenoiSeg paper (https://arxiv.org/abs/2005.02987)
<p>Mouse n20 dataset for microscopy image denoising and segmentation benchmark as used in DenoiSeg paper (https://arxiv.org/abs/2005.02987)</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.