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448 results for “Optical tomography”
Quantitative analysis of optical coherence tomography for neovascular age-related macular degeneration using deep learning
<p><strong>Purpose:</strong> To apply a deep learning algorithm for automated, objective, and comprehensive quantification of optical coherence tomography (OCT) scans to a large real-world dataset of eyes with neovascular age-related macular degeneration (AMD), and make the raw segmentation output data openly available for further research.</p> <p><strong>Design:</strong> Retrospective analysis of OCT images from the Moorfields Eye Hospital AMD Database.</p> <p><strong>Participants:</strong> 2473 first-treated eyes and another 493 second-treated eyes that commenced therapy for neovascular AMD between June 2012 and June 2017.</p> <p><strong>Methods:</strong> A deep learning algorithm was used to segment all baseline OCT scans. Volumes were calculated for segmented features such as neurosensory retina (NSR), drusen, intraretinal fluid (IRF), subretinal fluid (SRF), subretinal hyperreflective material (SHRM), retinal pigment epithelium (RPE), hyperreflective foci (HRF), fibrovascular pigment epithelium detachment(fvPED), and serous PED (sPED). Analyses included comparisons between first and second eyes, by visual acuity (VA) and by race/ethnicity, and correlations between volumes.</p> <p><strong>Main outcome measures:</strong> Volumes of segmented features (mm3), central subfield thickness (CST).</p> <p><strong>Results:</strong> In first-treated eyes, the majority had both IRF and SRF (54.7%). First-treated eyes had greater volumes for all segmented tissues, with the exception of drusen, which was greater in second-treated eyes. In first-treated eyes, older age was associated with lower volumes for RPE, SRF, NSR and sPED; in second-treated eyes, older age was associated with lower volumes of NSR, RPE, sPED, fvPED and SRF. Eyes from black individuals had higher SRF, RPE and serous PED volumes, compared with other ethnic groups. Greater volumes of the vast majority of features were associated with worse VA.</p> <p><strong>Conclusion:</strong> We report the results of large scale automated quantification of a novel range of baseline features in neovascular AMD. Major differences between first and second-treated eyes, with increasing age, and between ethnicities are highlighted. In the coming years, enhanced, automated OCT segmentation may assist personalization of real-world care, and the detection of novel structure-function correlations. These data will be made publicly available for replication and future investigation by the AMD research community.</p>
Deep-tissue label-free quantitative optical tomography
<p>Deep-tissue label-free quantitative optical tomography</p> <p>Jelle van der Horst, Anna K. Trull, and Jeroen Kalkman</p> <p>The data sets, software, and figures accompany the publication:</p> <p>"Deep-tissue label-free quantitative optical tomography", Optica 7, 1682 (2020) <a href="https://doi.org/10.1364/OPTICA.397549">https://doi.org/10.1364/OPTICA.397549</a></p> <ul> <li>calc_hilbert_cor.m, corrects OCT data for dispersion</li> <li>cascade_measurement.m, analysis of OCT reference data<\li></li> <li>data_A2_polyfit_v1_slice_0198.zip, Peak fitted data for all 200 slices (200 files)<\li></li> <li>Ex18-11-01B, spectral-domain OCT reference data<\li></li> <li>Ex18-11-01D, spectral-domain OCT reference data for background<\li></li> <li>Ex18-11-01E_sweep_0001.dat, Reference power distribution of a sweep<\li></li> <li>loadframes_refdata.m, load spectral-domain OCT data<\li></li> <li>manual_COR_correction.m, perform manual center of rotation correction<\li></li> <li>run_frame_analysis_polyfit.m, fit spatial-domain OCT data<\li></li> <li>run_tomo_ocpt.m, main MATLAB file for the reconstruction <\li></li> <li>shift_correction_galvo.m, correction for galvo offset<\li></li> </ul>
Replication Data for: OPTICAL COHERENCE TOMOGRAPHY IDENTIFIES LOWER LABIAL SALIVARY GLAND SURFACE DENSITY IN CYSTIC FIBROSIS
<p>Swept-source optical coherence tomography images of the mucosa of the lower lip acquired in 18 cystic fibrosis patients (CF.zip, includes an XLS file with additional data) and 18 healthy volunteers (HS.zip). Within the volumetric datasets consisting of sets of images the labial salivary glands can be identified.</p> <p>Authors: Nowak JK, Grulkowski I, Karnowski K, Wojtkowski M, Walkowiak J.<br /> When using the data, please always refer to the original paper (currently under review in PLOS ONE; title as specified above).</p> <p>The methodology used to obtain the volumetric datasets is described in:<br /> Grulkowski I, Nowak JK, Karnowski K, Zebryk P, Puszczewicz M, Walkowiak J, Wojtkowski M. Quantitative assessment of oral mucosa and labial minor salivary glands in patients with Sjögren’s syndrome using swept source OCT. Biomedical Optics Express, Vol. 5, Issue 1, pp. 259-274 (2014). DOI: http://dx.doi.org/10.1364/BOE.5.000259</p>
In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography (Data and 3D models)
<p>These files contain 3D models and reconstructions of the 3D printed models after OCT imaging of the brain stem, circle of willis, kidney, vestibular apparatus, mixing network, and resolution text. These are from the journal article "In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography" published in <em>Biofabrication </em>(2022).</p>
Negative Vessel Remodeling in Stargardt Disease Quantified with Volume-Rendered Optical Coherence Tomography Angiography
<p>Data underlying the figures in the publication “Negative Vessel Remodeling in Stargardt Disease Quantified with Volume-Rendered Optical Coherence Tomography Angiography”, published in Retina, <strong>2021</strong>. Doi: 10.1097/IAE.0000000000003110</p> <p>Table of contents:</p> <p><strong>1. Dataset 1</strong>; Excel sheet containing the source data of the publication.</p>
Choroidal thickness measurement in central serous chorioretinopathy using swept source optical coherence tomography: an observational study
<p><strong>Choroidal thickness </strong><strong>measurement in central serous chorioretinopathy using swept source optical coherence tomography: an observational study </strong></p>
Diagnostic Accuracy of Optical Coherence Tomography in Upper Urinary Tract Urothelial Carcinoma
ClinicalTrials.gov study NCT02326909. IPD Sharing: Not stated. Countries: 1. Publications: 1.
DETErmination of the Duration of the Dual Antiplatelet Therapy by the Degree of the Coverage of The Struts on Optical Coherence Tomography From the Randomized Comparison Between Everolimus-eluting Ste
ClinicalTrials.gov study NCT01752894. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Evaluation of Laser Treatment for Benign Pigmented Lesions by Non-invasive, Cellular Resolution Optical Coherence Tomography
ClinicalTrials.gov study NCT04861246. IPD Sharing: NO. Countries: 1. Publications: 10.
Laser Speckle Flowgraphy in Caucasians: Age Dependence and Comparison With Doppler Optical Coherence Tomography
ClinicalTrials.gov study NCT02582411. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Massachusetts General Hospital Optical Coherence Tomography Registry
ClinicalTrials.gov study NCT01110538. IPD Sharing: Not stated. Countries: 1. Publications: 17.
Intra-patient Study With Polymer Free Drug Eluting Stent Versus Abluminal Biodegradable Polymer Drug Eluting Stent With Early OCT (Optical Coherence Tomography) Follow up
ClinicalTrials.gov study NCT02785237. IPD Sharing: Not stated. Countries: 1. Publications: 32.
High Resolution Optical Coherence Tomography
ClinicalTrials.gov study NCT05130385. IPD Sharing: Not stated. Countries: 1. Publications: 16.
Optical Coherence Tomography to Evaluate Paclitaxel-Eluting Balloons and Everolimus-Eluting Coronary Stents
ClinicalTrials.gov study NCT01056744. IPD Sharing: Not stated. Countries: 1. Publications: 2.
The Optical Coherence Tomography in Age-Related Macular Degeneration Study: The OCT in AMD Study
ClinicalTrials.gov study NCT00531141. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Near Infrared Optical Coherence Tomography of the Upper Aero-Digestive Tract
ClinicalTrials.gov study NCT00544427. IPD Sharing: Not stated. Countries: 1. Publications: 1.
High-Resolution Optical Coherence Tomography for Detection of Retinal Nerve Fiber Layer Loss in Band Atrophy of the Optic Nerve
ClinicalTrials.gov study NCT00607100. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Percutaneous Coronary Intervention With the Angiolite Drug-eluting Stent: an Optical Cohenrece Tomography Study
ClinicalTrials.gov study NCT02776267. IPD Sharing: UNDECIDED. Countries: 1. Publications: 21.
Pulmonary Optical Coherence Tomography in COVID-19 Patients
ClinicalTrials.gov study NCT04410549. IPD Sharing: NO. Countries: 2. Publications: 11.
Optical Coherence Tomography Angiography Examinations in Chronic Retinal Artery Occlusion
ClinicalTrials.gov study NCT03357146. IPD Sharing: NO. Countries: 1. Publications: 7.
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.