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Dataset results

214 results for “Preclinical models”

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geo24/100

Mesothelioma location influences the tumour microenvironment and immune checkpoint therapy response in preclinical models

GEO Series GSE310501. Mus musculus. 31 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2025View details →
geo24/100

Therapeutic efficacy of FASN inhibition in preclinical models of HCC

GEO Series GSE189529. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2022View details →
geo24/100

CRISPR repair in a preclinical model of Noonan syndrome associated cardiomyopathy I

GEO Series GSE145348. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2020View details →
geo24/100

Multi-model preclinical platform predicts clinical response of melanoma to immunotherapy

GEO Series GSE144946. Mus musculus. 54 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenJun 2020View details →
geo24/100

Bacteroides thetaiotaomicron ameliorates colon inflammation in preclinical models of Crohn’s Disease [Bacteroides]

GEO Series GSE118525. Bacteroides thetaiotaomicron VPI-5482. 10 samples. Type: Expression profiling by array.

openGEO-OpenMar 2019View details →
geo24/100

Targeting Pancreatic Cancer by TAK-981, a SUMOylation Inhibitor that Activates the Immune System and Blocks Cancer Cell Cycle Progression in a Preclinical Model

GEO Series GSE189576. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2022View details →
geo24/100

Bacteroides thetaiotaomicron ameliorates colon inflammation in preclinical models of Crohn’s Disease

GEO Series GSE118526. Mus musculus; Bacteroides thetaiotaomicron VPI-5482. 18 samples. Type: Expression profiling by array.

openGEO-OpenMar 2019View details →
geo24/100

Rational selection of syngeneic preclinical tumor models for immunotherapeutic drug discovery [aCGH]

GEO Series GSE85508. Mus musculus. 16 samples. Type: Genome variation profiling by genome tiling array.

openGEO-OpenDec 2016View details →
geo24/100

A novel irreversible TEAD inhibitor, SWTX-143, blocks the Hippo pathway and causes tumor regression in preclinical mesothelioma models [Invitro]

GEO Series GSE222960. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo24/100

PPARα and PPARγ activation is associated with pleural mesothelioma invasion, but therapeutic inhibition is ineffective in preclinical models

GEO Series GSE180618. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2021View details →
geo24/100

Targeting T cell plasticity by pooled single cell CRISPR-screening in preclinical models of kidney and gut inflammation

GEO Series GSE267740. Mus musculus; Homo sapiens. 56 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenJun 2024View details →
geo24/100

ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models

GEO Series GSE178211. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2024View details →
geo24/100

Pharmacological inhibition of SIRT1 limits the growth of ovarian granulosa cell tumors in vitro and in preclinical mouse models

GEO Series GSE252773. Mus musculus; Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2024View details →
geo24/100

A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studies (RNA-Seq)

GEO Series GSE145557. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2021View details →
geo24/100

A Syngeneic ErbB2 Mammary Cancer Model for Preclinical Immunotherapy Trials [RNA-seq]

GEO Series GSE113379. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2019View details →
geo24/100

Restoration of branched chain amino acid catabolism improves kidney function in preclinical cardiovascular-kidney-metabolic syndrome models

GEO Series GSE263155. Rattus norvegicus. 120 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2025View details →
geo24/100

High-specificity CRISPR-mediated genome engineering in CB-011, an anti-BCMA allogeneic CAR-T cell, suppresses allograft rejection in preclinical models

GEO Series GSE249316. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2024View details →
geo24/100

The lower the better? Impact of radiation dose reduction on radiation-induced lung fibrosis molecular signature: approach towards preclinical model perfection

GEO Series GSE205025. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2024View details →
geo24/100

TGF-beta-activated cancer-associated fibroblasts limit cetuximab efficacy in preclinical models of head and neck cancer

GEO Series GSE143279. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2020View details →
geo24/100

Integration of human stem cell-derived in vitro systems and mouse preclinical models identifies complex pathophysiologic mechanisms in retinal dystrophy [human_retinal_organoid]

GEO Series GSE220624. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2023View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record