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Dataset results
84 results for “Pyrimidines”
Combined single-sample metabolomics and RNAseq reveals a hepatic pyrimidine metabolic response to acute viral infection
GEO Series GSE226930. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing.
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T-cell development [bulk RNA-seq]
GEO Series GSE200358. Mus musculus. 39 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq data for: Anti-retroviral treatment with zidovudine alters pyrimidine metabolism, reduces translation, and extends healthy longevity via ATF-4
GEO Series GSE150108. Caenorhabditis elegans. 8 samples. Type: Expression profiling by high throughput sequencing.
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation
GEO Series GSE85510. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Extracellular adenine released by the cardiac muscle cell disrupts pyrimidine biosynthesis in non-muscle cells to regulate tissue repair after heart injury
GEO Series GSE185060. Mus musculus. 37 samples. Type: Expression profiling by high throughput sequencing.
Ectopic expression of cytosolic DHODH uncouples de novo pyrimidine biosynthesis from mitochondrial electron transport
GEO Series GSE314127. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Inhibition of pyrimidine biosynthesis targets protein translation in AML [RNA-seq_RUNX1]
GEO Series GSE181664. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Pan-cancer analysis of pyrimidine metabolism using pathway-based approach unravels complex signaling pathways connections with a role in chemoresistance
GEO Series GSE248686. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Disulfiram treatment suppresses antibody-producing reactions by inhibiting macrophage activation and B cell pyrimidine metabolism
GEO Series GSE261712. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.
Inhibition of pyrimidine biosynthesis targets protein translation in AML [RNA-seq_MN-2]
GEO Series GSE181662. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Melanoma mutations are caused by deamination of cytosine in pyrimidine dimers
GEO Series GSE159807. Homo sapiens; Mus musculus. 9 samples. Type: Other.
Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers
GEO Series GSE119249. Homo sapiens. 5 samples. Type: Other.
Characterization of cyclobutane pyrimidine dimer-dependent modulation of gene expression in human keratinocytes following UVB exposure
GEO Series GSE65034. Homo sapiens. 18 samples. Type: Expression profiling by array.
Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase
GEO Series GSE148688. Homo sapiens. 24 samples. Type: Other.
Pyrimidine Triones as Potential Activators of p53 Mutants
GEO Series GSE273169. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
De Novo Pyrimidine Synthesis Is a Collateral Metabolic Vulnerability in NF2-deficient Mesothelioma
GEO Series GSE295651. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity [A33_OE_RNA-seq]
GEO Series GSE161732. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Figure 1 from: Severina HI, Skupa OO, Voloshchuk NI, Suleiman MM, Georgiyants VA (2019) Synthesis and anticonvulsant activity of 6-methyl-2-((2-oxo-2-arylethyl)thio)pyrimidin-4(3 H)-one derivatives and products of their cyclization. Pharmacia 66(3): 141-146. https://doi.org/10.3897/pharmacia.66.e38137
Figure 1 Pharmacophore fragments that may affect anticonvulsant activity.
Figure 3 from: Bulbul MZH, Chowdhury TS, Misbah MMH, Ferdous J, Dey S, Hasan I, Fujii Y, Ozeki Y, Kawsar SMA (2021) Synthesis of new series of pyrimidine nucleoside derivatives bearing the acyl moieties as potential antimicrobial agents. Pharmacia 68(1): 23-34. https://doi.org/10.3897/pharmacia.68.e56543
Figure 3 MIC values for compounds 7, 9, and 14.
Figure 6 from: Bulbul MZH, Chowdhury TS, Misbah MMH, Ferdous J, Dey S, Hasan I, Fujii Y, Ozeki Y, Kawsar SMA (2021) Synthesis of new series of pyrimidine nucleoside derivatives bearing the acyl moieties as potential antimicrobial agents. Pharmacia 68(1): 23-34. https://doi.org/10.3897/pharmacia.68.e56543
Figure 6 MIC and MFC values for the compounds 7 and 14.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.