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Dataset results
411 results for “Radiation dose”
Low Dose Ionizing Radiation Using CT Scans as a Potential Therapy for Alzheimer's Dementia: A Pilot Study
ClinicalTrials.gov study NCT03597360. IPD Sharing: NO. Countries: 1. Publications: 17.
Data from: Probabilistic interfractional motion carbon ion radiation therapy dose distribution for prostate cancer shows rectum sparing with moderate target coverage degradation
Purpose: This observational study investigates the influence of interfractional motion on clinical target volume (CTV) coverage, planning target volume (PTV) margins, and rectum tissue sparing in carbon ion radiation therapy (CIRT). It reports dose coverage to target structures and organs at risk in the presence of interfractional motion, investigates rectal tissue sparing, and provides recommendations for further lowering the rate of toxicity. We also propose probabilistic DVH for consideration in treatment planning to represent probable dose to the clinic's patient population. Methods: At Gunma University Hospital intensity-modulated x-ray therapy (IMXT, aka IMRT) prostate cancer patients are positioned on a table which is shifted twice based on cone-beam computed tomography (CBCT) to align bones and then align prostate tissue to isocenter. These shifts thereby contain interfractional motion. 1306 such tableshifts from 85 patients were collected. Normal probability distributions were fit to the difference between bone-matching and prostate-matching CBCT-to-planning CT tableshifts (i.e. interfractional motion). Between 2011 and 2016 CIRT prostate patients were treated with PTV1 and PTV2 margins as follows: PTV1 extends the prostate contour by 10/10, 5/10, 6/6 mm in the right/left, posterior/anterior, and superior/inferior directions, respectively, and the proximal seminal vesicles contour by 5 mm superiorly and inferiorly, 3 mm right and left. PTV2 reduces PTV1 posteriorly along a straight line to exclude the rectum and reduces the superior and inferior margins by 6 mm. From those treated with these margins, 40 patients' beam data were selected to create probable interfractional motion: The previously fit normal probability distributions were randomly sampled 2000 times per patient and beams shifted to simulate this motion. These shifted dose distributions were scaled down proportionately in magnitude and summed to obtain probable blurred dose distributions. Results: Probable dose to rectum is substantially less than planned for doses higher than 10 Gy(RBE). Absolute DVH show that mean clinical target volumes are about 138-670 cm3 smaller for a given probable dose than planned doses higher than 57 Gy(RBE) after accounting for standard error. Cumulative DVH show mean CTV fraction receiving a given probable dose is less than the mean fraction receiving the corresponding planned dose for doses larger than 52 Gy(RBE), up to 19% less at 57.4 Gy(RBE). Our PTV1 margins generally cover 95% of interfractional motion but seminal vesicles and inferior prostate receive less dose than planned due to insufficient PTV2 margins. Conclusion: Assuming rigidly shifting interfractional motion around the prostate region and neglecting minor changes in soft tissue stopping power, interfractional motion resulted in underdosing or tissue sparing in all cases. Given our low rates of relapse and recurrence, it appears less curative dose is needed than previously thought or else the target may be smaller than previously thought. In-room CT may be useful to lower dose, shrink target margins, conduct PET auto-activation dose verification studies and account for interfractional motion.
Transcriptional and epigenetic profiling of Arabidopsis thaliana exposed to low dose ionizing radiation
<p>RNA and methylation profiling of Arabidopsis seedlings to low dose ionizing radiation</p>
CCR. Low-dose ionizing-radiation elicits the extrusion of neutrophil extracellular traps
Open the record for dataset details and reuse information.
SEP list and effective dose of paper "The radiation impact of Solar Energetic Particle Events on the Moon: A statistical study using data-based modeling results"
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Rectal Spacer Hydrogel Before Radiation Therapy in Reducing Radiation Dose to the Rectum in Patients With Prostate Cancer
ClinicalTrials.gov study NCT05224869. IPD Sharing: NO. Countries: 1. Publications: 1.
RADIQAL Study (Radiation Dose and Image Quality Trial)
ClinicalTrials.gov study NCT06944509. IPD Sharing: NO. Countries: 4. Publications: 6.
Prospective Multicenter Registry On RadiaTion Dose Estimates Of Cardiac CT AngIOgraphy IN Daily Practice in 2017
ClinicalTrials.gov study NCT02996903. IPD Sharing: NO. Countries: 4. Publications: 1.
Choice of Tube Extremity in Emission of Lowest Radiation Dose in Pediatric Patients
ClinicalTrials.gov study NCT02925936. IPD Sharing: NO. Countries: 1. Publications: 2.
Chemoradiotherapy With Elective Low Dose Nodal Radiation for Locally Advanced Head and Neck Cancer
ClinicalTrials.gov study NCT01372111. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Low-Dose Radiation to Prevent Complications of Back Surgery
ClinicalTrials.gov study NCT00018876. IPD Sharing: Not stated. Countries: 1. Publications: 19.
Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy
ClinicalTrials.gov study NCT01223248. IPD Sharing: Not stated. Countries: 3. Publications: 2.
High-Dose Rate Brachytherapy and Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer
ClinicalTrials.gov study NCT01655836. IPD Sharing: Not stated. Countries: 1. Publications: 25.
Ultra Low Dose Orbital Radiation Therapy in Treating Patients With Stage I-IV Indolent B-cell Lymphoma or Mantle Cell Lymphoma
ClinicalTrials.gov study NCT02494700. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Impact of Selective Radiation Dose Escalation and Tumour Hypoxia Status on Locoregional Tumour Control After Radiochemotherapy of HNT
ClinicalTrials.gov study NCT01212354. IPD Sharing: Not stated. Countries: 1. Publications: 2.
High Versus Low Dose Supplemental External Radiation With Pd-103 for Prostate Cancer
ClinicalTrials.gov study NCT00494546. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Long-term Benefit of Hydrogel Spacer in Reducing Rectal Radiation Dose in Cervical Cancer Radiation Therapy.
ClinicalTrials.gov study NCT05902390. IPD Sharing: YES. Countries: 1. Publications: 3.
Safety Study of the Hypo-fractionated (Large Doses) Radiation Therapy in Post-menopausal Women With Breast Cancers
ClinicalTrials.gov study NCT02883985. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Shared Decision Making on Radiation Dose for Lung Malignancies
ClinicalTrials.gov study NCT04940936. IPD Sharing: NO. Countries: 1. Publications: 1.
Clinical Trial of Low-dose Radiation Therapy in Patients With Knee Osteoarthritis (LoRD-KNeA Trial)
ClinicalTrials.gov study NCT05562271. IPD Sharing: NO. Countries: 1. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.