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154
datasets available to search
ShareScore release 0.9.0
Dataset results
154 results for “Reset”
Data for: Widespread wood placement and regrading drive lateral connectivity and reworking of the channel and floodplain in a valley bottom reset to stage 0
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Data from: Engineering repressors with coevolutionary cues facilitates toggle switches with a master reset
Engineering allosteric transcriptional repressors containing an environmental sensing module (ESM) and a DNA recognition module (DRM) has the potential to unlock a combinatorial set of rationally designed biological responses. We demonstrated that constructing hybrid repressors by fusing distinct ESMs and DRMs provides a means to flexibly rewire genetic networks for complex signal processing. We have used coevolutionary traits among LacI homologs to develop a model for predicting compatibility between ESMs and DRMs. Our predictions accurately agree with the performance of 40 engineered repressors. We have harnessed this framework to develop a system of multiple toggle switches with a master OFF signal that produces a unique behavior: each engineered biological activity is switched to a stable ON state by different chemicals and returned to OFF states in response to a common signal. One promising application of this design is to develop living diagnostics for monitoring multiple parameters in complex physiological environments and it represents one of many circuit topologies that can be explored with modular repressors designed with coevolutionary information.
reSET-O RCT (Randomized Controlled Trial)
ClinicalTrials.gov study NCT04129580. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Failed on One Prior Anti-TNF Therapy (RESET)
ClinicalTrials.gov study NCT01272908. IPD Sharing: Not stated. Countries: 2. Publications: 0.
ReSET Aim 1a: Restarting Safe Education and Testing for Children With Medical Complexity - Feasibility of In-home Cohort COVID-19 Testing Strategies, and Associations With CMC Parent Perceptions About
ClinicalTrials.gov study NCT04895085. IPD Sharing: NO. Countries: 1. Publications: 0.
Phase 2 Study of Ruxolitinib Versus Anagrelide in Subjects With Essential Thrombocythemia Who Are Resistant to or Intolerant of Hydroxyurea (RESET-272)
ClinicalTrials.gov study NCT03123588. IPD Sharing: NO. Countries: 1. Publications: 0.
RESET Trial - Part 1 - A Phase 3 Trial in Subjects With Sjögren-Larsson Syndrome (SLS)
ClinicalTrials.gov study NCT03445650. IPD Sharing: NO. Countries: 1. Publications: 0.
ReSET Aim 1b: Restarting Safe Education and Testing for Children With Medical Complexity - COVID-19 Testing in School With Children and Staff
ClinicalTrials.gov study NCT04899245. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Temperature-dependent resetting of the molecular circadian oscillator in Drosophila.
Open the record for dataset details and reuse information.
Data from: Engineering repressors with coevolutionary cues facilitates toggle switches with a master reset
Open the record for dataset details and reuse information.
Resetting epigenetic memory by reprogramming of histone modifications in mammals
GEO Series GSE76687. Mus musculus. 27 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Resetting proteostasis in aged animals with ISRIB prevents recruitment of profibrotic monocyte-derived alveolar macrophages during pulmonary fibrosis [AT2]
GEO Series GSE145771. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic resetting of human pluripotency
GEO Series GSE90168. Homo sapiens. 11 samples. Type: Methylation profiling by high throughput sequencing.
Reproduction of reset cell
GEO Series GSE66657. Homo sapiens. 3 samples. Type: Expression profiling by array.
Gene expression in primed, coculture with mouse ESC, coculture-derived naïve-like state, and chemically reset (cR) naïve human H9 ESCs.
GEO Series GSE272112. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Targeted reprogramming of H3K27me3 resets epigenetic memory in plant paternal chromatin
GEO Series GSE120668. Arabidopsis thaliana. 3 samples. Type: Expression profiling by high throughput sequencing; Third-party reanalysis.
Left ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart
GEO Series GSE237040. Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Low Dose Pro-resolving Mediators Reset the Resolution Response to Microbial Inflammation
GEO Series GSE270972. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Stress Resets Transgenerational Small RNA Inheritance
GEO Series GSE129988. Caenorhabditis elegans. 24 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Resetting proteostasis in aged animals with ISRIB prevents recruitment of profibrotic monocyte-derived alveolar macrophages during pulmonary fibrosis
GEO Series GSE145295. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.