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235 results for “Stimulus”
Stimulus presentation can enhance spiking irregularity across subcortical and cortical regions
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How animals discriminate between stimulus magnitudes: a meta-analysis
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Adult-born granule cells improve stimulus encoding and discrimination in the dentate gyrus
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Replicating Attribute Amnesia effect in the single-stimulus design
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Data from: Stimulus dependent emergence of understanding analogical relations in budgerigars
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Sequential maturation of stimulus-specific adaptation in the mouse lemniscal auditory system
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Stimulus encoding by specific inactivation of cortical neurons
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Supporting information for: Discrimination ability of central visual field testing using stimulus size I, II, and III and relationship with macular ganglion cell thickness in chiasmal compression
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Discomfort due to glare from a large source: Evaluating stimulus range effects when using the luminance adjustment procedure
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Link to dataset related to article "Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells"
<p>Accessibility of the genomic regulatory information is largely controlled by the nucleosome-organizing activity of transcription factors (TFs). While stimulus-induced TFs bind to genomic regions that are maintained accessible by lineage-determining TFs, they also increase accessibility of thousands of <em>cis</em>-regulatory elements. Nucleosome remodeling events underlying such changes and their interplay with basal positioning are unknown. Here, we devised a novel quantitative framework discriminating different types of nucleosome remodeling events in micrococcal nuclease ChIP-seq (chromatin immunoprecipitation [ChIP] combined with high-throughput sequencing) data sets and used it to analyze nucleosome dynamics at stimulus-regulated <em>cis</em>-regulatory elements. At enhancers, remodeling preferentially affected poorly positioned nucleosomes while sparing well-positioned nucleosomes flanking the enhancer core, indicating that inducible TFs do not suffice to overrule basal nucleosomal organization maintained by lineage-determining TFs. Remodeling events appeared to be combinatorially driven by multiple TFs, with distinct TFs showing, however, different remodeling efficiencies. Overall, these data provide a systematic view of the impact of stimulation on nucleosome organization and genome accessibility in mammalian cells.</p>
Neutron Reflectometry data and code for the manuscript entitled: 'Enrichment of charged monomers explains non-monotonic polymer volume fraction profiles of multi-stimulus responsive copolymer brushes'
<p>Contained in the zip file is the reduced neutron reflectometry data, the code used to analyse the data and jupyter notebooks used implement this code. Data is for proposal number PP4274, experiment number PPR6490 on the Platypus Reflectometer at ANSTO, Australia. The data is name with measurement numbers. The attached excel document describes the condition which corresponds to measurement number. </p>
Data from: Stimulus discriminability may bias value-based probabilistic learning
Reinforcement learning tasks are often used to assess participants' tendency to learn more from the positive or more from the negative consequences of one's action. However, this assessment often requires comparison in learning performance across different task conditions, which may differ in the relative salience or discriminability of the stimuli associated with more and less rewarding outcomes, respectively. To address this issue, in a first set of studies, participants were subjected to two versions of a common probabilistic learning task. The two versions differed with respect to the stimulus (Hiragana) characters associated with reward probability. The assignment of character to reward probability was fixed within version but reversed between versions. We found that performance was highly influenced by task version, which could be explained by the relative perceptual discriminability of characters assigned to high or low reward probabilities, as assessed by a separate discrimination experiment. Participants were more reliable in selecting rewarding characters that were more discriminable, leading to differences in learning curves and their sensitivity to reward probability. This difference in experienced reinforcement history was accompanied by performance biases in a test phase assessing ability to learn from positive vs. negative outcomes. In a subsequent large-scale web-based experiment, this impact of task version on learning and test measures was replicated and extended. Collectively, these findings imply a key role for perceptual factors in guiding reward learning and underscore the need to control stimulus discriminability when making inferences about individual differences in reinforcement learning.
Supplementary Figure 6 stimulus induced brain activity data
<p>This data set shows brain activity in response to an airpuff stimulus applied to the right whiskers. A 2 s, 3 Hz airpuff stimulus is applied to the right whiskers 20 times. This data was collected using a CMOS camera that costs approximately $750. Wide field images of the mouse brain at four different wavelengths are provided as .tif files. Processed data are included in a .h5 file that contains relative changes in neuronal calcium activity, extracellular acetylcholine, oxyhemoglobin, and deoxyhemoglobin. A trigger file recorded by the data acquisition system shows the timing of measurements and stimuli. This data was used to produce the stimulus response parts of supplementary figure 6 in the following article.</p> <p>Doran, P., Fomin-Thunemann, N., Tang, R., Zimmerman, B., Kilic, K., Kura, S., Fisher, H., Chabbot, G., Herbert, J., Jiang, J., Sakadzic, S., Boas, D., Devor, A., Chen, I., & Thunemann, M. (2023). Widefield in vivo imaging system with two fluorescence and two reflectance channels, a single sCMOS detector, and shielded illumination. bioRxiv. <a href="https://doi.org/https:/doi.org/10.1101/2023.11.07.566086do">https://doi.org/https://doi.org/10.1101/2023.11.07.566086do</a></p>
Figure 2 stimulus induced brain activity data
<p>This data set shows brain activity in response to an airpuff stimulus applied to the right whiskers. A 2 s, 3 Hz airpuff stimulus is applied to the right whiskers 20 times. Raw .dat files produced by the camera contain wide field images of the mouse brain collected at four different wavelengths. Processed data are included in a .h5 file that contains relative changes in neuronal calcium activity, extracellular acetylcholine, oxyhemoglobin, and deoxyhemoglobin. A video of the mouse face and a recording from an accelerometer placed under the mouse are also included. A trigger file recorded by the data acquisition system shows the timing of measurements and stimuli. This data was used to produce the stimulus response parts of figure 2 in the following article.</p> <p>Doran, P., Fomin-Thunemann, N., Tang, R., Zimmerman, B., Kilic, K., Kura, S., Fisher, H., Chabbot, G., Herbert, J., Jiang, J., Sakadzic, S., Boas, D., Devor, A., Chen, I., & Thunemann, M. (2023). Widefield in vivo imaging system with two fluorescence and two reflectance channels, a single sCMOS detector, and shielded illumination. bioRxiv. <a href="https://doi.org/https:/doi.org/10.1101/2023.11.07.566086do">https://doi.org/https://doi.org/10.1101/2023.11.07.566086do</a></p>
Code for the paper "Visual experience orthogonalizes visual cortical stimulus responses via popula-tion code transformation"
<p>This repository contains data analysis code for the paper <a href="https://www.biorxiv.org/content/10.1101/2021.05.23.445338v4">Visual experience orthogonalizes visual cortical stimulus responses via population code transformation</a> by Failor, Carandini and Harris.</p> <p>The main data for the paper can be found <a href="https://figshare.com/articles/dataset/Data_from_paper_Visual_experience_orthogonalizes_visual_cortical_stimulus_responses_via_population_code_transformation_/27855423">here</a> in standardized <a href="https://www.ucl.ac.uk/cortexlab/open-neurophysiology-environment">ONE format</a>. Some of the analysis code in the current repository uses files in a non-standard internal format; data files in this format can be found <a href="https://doi.org/10.6084/m9.figshare.27890820.v1">here</a>.</p>
Increasing stimulus similarity drives nonmonotonic representational change in hippocampus
<p>Studies of hippocampal learning have obtained seemingly contradictory results, with manipulations that increase coactivation of memories sometimes leading to differentiation of these memories, but sometimes not. These results could potentially be reconciled using the nonmonotonic plasticity hypothesis, which posits that representational change (memories moving apart or together) is a U-shaped function of the coactivation of these memories during learning. Testing this hypothesis requires manipulating coactivation over a wide enough range to reveal the full U-shape. To accomplish this, we used a novel neural network image synthesis procedure to create pairs of stimuli that varied parametrically in their similarity in high-level visual regions that provide input to the hippocampus. Sequences of these pairs were shown to human participants during high-resolution fMRI. As predicted, learning changed the representations of paired images in the dentate gyrus as a U-shaped function of image similarity, with neural differentiation occurring only for moderately similar images.</p>
Datasets for "Efficient snap-through of spherical caps by applying a localized curvature stimulus", L. Stein-Montalvo et al., EPJE (2022)
<p>Data from experiments and simulations in "Efficient snap-through of spherical caps by applying a localized curvature stimulus", by L. Stein-Montalvo et al., in the European Physics Journal E (2022) doi: 10.1140/epje/s10189-021-00156-0</p>
Raw data for: Captivating color: evidence for optimal stimulus design in a polymorphic prey lure
<p><span>Many species – humans included – employ color as an instrument of deception. One intriguing example of this resides in the conspicuous abstract color patterns displayed on the bodies of female orb weaving spiders. These displays increase prey interception rates and thereby function at least as visual lures. Their chromatic properties however vary extensively, both across and within species, with discrete forms often co-existing in the manner of a stable polymorphism. Variation is principally expressed in terms of signal hue (color <em>per se</em>), but it is unclear how attractiveness scales with this property and if extant morphs are maximally attractive relative to a graded range of potential alternatives. We examined these questions by assessing catch rates among color-manipulated females of the dimorphic jeweled spider <em>Gasteracantha fornicata</em> in their natural webs. The manipulation altered dorsal appearance in a manner akin to adding six new variants of their existing white/yellow phenotypes. This magnified the natural variation in stimulus hue independently of chroma (saturation) across a range spanning most of the color spectrum. Catch rate varied across treatments in simple accordance with how greatly stimulus hue deviated from either of the two extant spider phenotypes. Predictions based upon fly-perceived chromatic and achromatic background contrast were clearly unsupported despite dipterans constituting ~60 % of identifiable prey. This study supports the importance of signal coloration <em>per se</em> in </span><em><span>G. fornicata</span></em><span> and suggests that </span><span>extant lure phenotypes reside in a broadly optimal spectral range for stimulating their aggregate prey community.</span></p>
Mechanical and thermal thresholds before and after application of a conditioning stimulus in healthy Göttingen Minipigs
<p>Mechanical and thermal thresholds, Von Frey thresholds, physiological parameters and feasibility scores of healthy adult minipigs before and after the application of a conditioning stimulus.</p>
Numerical source data for the manuscript Stimulus duration encoding occurs early in the moth olfactory pathway
<p>Numerical source data for the manuscript Stimulus duration encoding occurs early in the<br>moth olfactory pathway published in Communications Biology</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.