Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
69
datasets available to search
ShareScore release 0.9.0
Dataset results
69 results for “Stroke Disease”
Stroke induces disease-specific myeloid cells in the brain parenchyma and pia
GEO Series GSE189432. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Data from: Imaging markers of small vessel disease and 'brain frailty' and outcomes in acute stroke
Objective: We assessed the association of baseline imaging markers of cerebral small vessel disease (SVD) and 'brain frailty' with clinical outcome after acute stroke in the Efficacy of Nitric Oxide in Stroke (ENOS) trial. Methods: ENOS randomised 4011 patients with acute stroke (<48 hours of onset) to transdermal glyceryl trinitrate (GTN) or no GTN for 7 days. The primary outcome was functional outcome (modified Rankin Scale, mRS) at day 90. Cognition was assessed via telephone at day 90. Stroke syndrome was classified using the Oxfordshire Community Stroke Project classification. Brain imaging was adjudicated masked to clinical information and treatment, and assessed SVD (leukoaraiosis, old lacunar infarcts/lacunes, atrophy) and 'brain frailty' (leukoaraiosis, atrophy, old vascular lesions/infarcts). Analyses used ordinal logistic regression adjusted for prognostic variables. Results: In all participants and those with lacunar syndromes (LACS, 1397, 34.8%), baseline CT imaging features of SVD and 'brain frailty' were common and independently associated with unfavourable shifts in mRS at day 90: all participants (SVD score OR 1.15, 95% CI 1.07-1.24; 'brain frailty' score OR 1.25, 95% CI 1.17-1.34); those with LACS (SVD score OR 1.30, 95% CI 1.15-1.47; 'brain frailty' score OR 1.28, 95% CI 1.14-1.44). 'Brain frailty' was associated with worse cognitive scores at 90 days in all and in LACS participants. Conclusions: Baseline imaging features of SVD and 'brain frailty' were common in lacunar stroke and all stroke, predicted worse prognosis after all acute stroke with a stronger effect in lacunar stroke, and may aid future clinical decision-making. Registration: ISRCTN99414122.
Prescription and Persistence of Antithrombotic Agents in Acute Ischemic Stroke or Transient Ischemic Attack Patients With MCA(Middle Cerebral Artery) Disease
ClinicalTrials.gov study NCT02953405. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluating Barriers to Stroke Screening and Prevention in Children With Sickle Cell Disease
ClinicalTrials.gov study NCT03621826. IPD Sharing: NO. Countries: 1. Publications: 0.
Randomised Control Trial for Improving Functional Outcome From Stroke in End Stage Renal Disease Patients
ClinicalTrials.gov study NCT01656213. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Investigation of Genetic Disease Marker Associated With Spontaneous Haemorrhagic Stroke Complicating Severe Pre-eclampsia in Pregnancy
ClinicalTrials.gov study NCT05121415. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Consequences of the COVID-19 Lockdown on Health and Well-being of Patients With Parkinson Disease and Post-stroke
ClinicalTrials.gov study NCT04535297. IPD Sharing: NO. Countries: 1. Publications: 0.
Prevalence and Characteristics of Fabry Disease (FD) in Patients With Stroke or Small Fiber Neuropathy
ClinicalTrials.gov study NCT03230149. IPD Sharing: NO. Countries: 1. Publications: 0.
SmartRisk Stroke Prediction by MRI of Carotid Disease
ClinicalTrials.gov study NCT00860184. IPD Sharing: Not stated. Countries: 1. Publications: 0.
BLANDISH (Brain, Loss of Function, Aneurism, Disease, Injury, Stroke, Hemorrhage)
ClinicalTrials.gov study NCT06320132. IPD Sharing: NO. Countries: 1. Publications: 0.
Small-vessel Disease Burden and Early Risk of Stroke After Transient Ischemic Attack
ClinicalTrials.gov study NCT04108754. IPD Sharing: NO. Countries: 1. Publications: 0.
Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease
ClinicalTrials.gov study NCT01236508. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Carotid Artery Disease After Stroke (CADAS).
ClinicalTrials.gov study NCT03721523. IPD Sharing: NO. Countries: 1. Publications: 0.
Cerebral Small Vessel Disease and Perioperative Covert Stroke
ClinicalTrials.gov study NCT04443933. IPD Sharing: YES. Countries: 1. Publications: 0.
Fabry and Stroke Epidemiological Protocol (FASEP): Risk Factors In Ischemic Stroke Patients With Fabry Disease
ClinicalTrials.gov study NCT01182818. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Stroke and Carotid-Cerebral Vascular Disease After CABG
ClinicalTrials.gov study NCT05036044. IPD Sharing: NO. Countries: 1. Publications: 0.
Stroke and Cerebrovascular Diseases Registry
ClinicalTrials.gov study NCT03281590. IPD Sharing: NO. Countries: 1. Publications: 0.
A Phase 2 Open-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary Stroke
ClinicalTrials.gov study NCT05953584. IPD Sharing: YES. Countries: 3. Publications: 0.
Epidemiology of Silent and Overt Strokes in Sickle Cell Disease
ClinicalTrials.gov study NCT03376893. IPD Sharing: NO. Countries: 1. Publications: 0.
Assessment of Coronary Artery Disease in Stroke Patients
ClinicalTrials.gov study NCT01850693. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.