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281 results for “Whole brain”
Data from: In vivo human whole-brain Connectom diffusion MRI dataset at 760 µm isotropic resolution (PART II)
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Whole brain imaging dataset (ASW, Butanol, Carvacrol) related to Hoyer et al
<p>Data related to the manuscript titled: Polymodal sensory perception drives robust attachment and metamorphosis of a pre-vertebrate zooplanktonic larva. </p>
Whole brain Calcium Imaging dataset (CsCl, 1mM NH4Cl, 100mM NH4Cl, SDS)
<p>Data related to the manuscript titled: Polymodal sensory perception drives robust attachment and metamorphosis of a pre-vertebrate zooplanktonic larva. </p>
Functional and structural computed connectivity profiles for pre-defined whole-brain and cortical hull maps
<p>This Repository holds Lead-DBS Lead-Mapper v.2.5.2 computed functional and structural estimated connectivity. The structural dMRI connectivity is computed based on the "HCP1000 6K" connecome and the fMRI connectivity "GSP 1000 Yeo 2011" connectome.</p> <p>Both connectivity metrices were computed using two pre-defined grids:</p> <ol> <li> Cortical hull (1025 points). The grid was estimated based on the <a href="https:/github.com/neuromodulation/py_neuromodulation/blob/main/py_neuromodulation/ConnectivityDecoding/_get_grid_hull.m">SPM cortex_20484 grid</a> and subsampled by every 20th point. The grid is saved as a <a href="(https:/github.com/neuromodulation/py_neuromodulation/blob/main/py_neuromodulation/ConnectivityDecoding/mni_coords_cortical_surface.mat)">.mat file</a> and can be acessed through the main repository .</li> <li>Whole-brain (1236 points). Given the Lead-DBS provided <a href="https://github.com/neuromodulation/py_neuromodulation/blob/main/py_neuromodulation/ConnectivityDecoding/Automated%20Anatomical%20Labeling%203%20(Rolls%202020).nii">AAL3 atlas</a> the whole-brain .nii grid is subsampled by a factor of 150. See here the <a href="https://github.com/neuromodulation/py_neuromodulation/blob/main/py_neuromodulation/ConnectivityDecoding/_get_grid_whole_brain.py">grid computation</a>.</li> </ol> <p>Both grids can be accessed trough the <a href="https://github.com/neuromodulation/py_neuromodulation/tree/main">py_neuromodulation</a> API using the <a href="https://github.com/neuromodulation/py_neuromodulation/blob/main/py_neuromodulation/nm_RMAP.py">nm_RMAP.py</a> module.</p>
Whole genome RNA-sequencing reveals modulation of genes related to brain disorders by Withania somnifera in human neuroblastoma SK-N-SH cells
<p>Table S1: Human reference genome based differential gene expression; Figure S1: Reactome Pathway (50 μg/mL_3h vs C_3h); Figure S2: Reactome Pathway (50 μg/mL_9h vs C_9h); Figure S3: Reactome pathway (100 μg/mL_3h vs C_3h); Figure S4: GO Dose comparison; Reactome pathway (100 μg/mL_3h vs 50 μg/mL_3h); Figure S5: GO Dose comparison; Reactome pathway (100 μg/mL_9h vs 50 μg/mL_9h); Figure S6: GO Time comparison; Reactome pathway (50 μg/mL_9h vs 50 μg/mL_3h); Figure S7: GO Time comparison; Reactome pathway (100 μg/mL_9h vs 100 μg/mL_3h); Table S2: Disease ontology analysis of 100 μg/mL_3h vs 50 μg/mL_3h WS-treated SK-N-SH cells; Table S3: Disease ontology analysis of 100 μg/mL_9h vs 50 μg/mL_9h WS-treated SK-N-SH cells; Table S4: Disease ontology analysis of 100 μg/mL_9h vs 100 μg/mL_3h WS-treated SK-N-SH cells.</p>
Whole human-brain mapping of single cortical neurons for profiling morphological diversity and stereotypy
<p>Quantifying neuron morphology and distribution at the whole brain scale is essential to understand the structure and diversity of cell types. It is exceedingly challenging to reuse recent technologies of single cell labeling and whole brain imaging to study human brains. We propose Adaptive Cell Tomography (ACTomography), a low-cost, high-throughput, high-efficacy tomography approach, based on adaptive targeting of individual cells. We established a platform to inject dyes into cortical neurons in surgical tissues of 18 patients with brain tumors or other conditions and 1 donated fresh postmortem brain. We collected 3-D images of 1746 cortical neurons, of which 852 neurons were reconstructed to quantify local dendritic morphology, and mapped to standard atlases. In our data, human neurons are more diverse across brain regions than by subject age or gender. The strong stereotypy within cohorts of brain regions allows generating a statistical tensor-field of neuron morphology to characterize anatomical modularity of a human brain.</p>
PET Brain and Whole Body Distribution Studies for Nociceptin/Orphanin FQ Peptide (NOP) Receptor Using [11C]NOP-1A
ClinicalTrials.gov study NCT01198197. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Whole Brain Radiotherapy Versus Volumetric Modulated Arc Therapy for Brain Metastases
ClinicalTrials.gov study NCT02220491. IPD Sharing: Not stated. Countries: 1. Publications: 20.
Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer
ClinicalTrials.gov study NCT06431685. IPD Sharing: NO. Countries: 1. Publications: 10.
Whole Brain Vessel Wall Imaging in Stroke Patients (WISP): An International Multi-Center Registry
ClinicalTrials.gov study NCT02923752. IPD Sharing: NO. Countries: 2. Publications: 2.
Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases
ClinicalTrials.gov study NCT02015117. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Randomized Trial Comparing Radiosurgery With vs Without Whole Brain Radiotherapy
ClinicalTrials.gov study NCT00548756. IPD Sharing: Not stated. Countries: 1. Publications: 1.
WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER)
ClinicalTrials.gov study NCT04891471. IPD Sharing: YES. Countries: 1. Publications: 1.
Assessment of [11C]ER176 to Image Translocator Protein in Brain and Whole Body of Healthy People
ClinicalTrials.gov study NCT02147392. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Chemotherapy and Whole-Brain Radiation Therapy in Treating Patients With Primary Central Nervous System Non- Hodgkin's Lymphoma
ClinicalTrials.gov study NCT00002676. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Neurocognitive Impact and Dose-Effect Relationship of Hippocampal Avoidance During Whole Brain Radiotherapy Plus Simultaneous Integrated Boost - A Prospective Follow-up Study
ClinicalTrials.gov study NCT03223675. IPD Sharing: NO. Countries: 1. Publications: 1.
A Prospective Study of the Impact of Hippocampal Avoidance During Whole Brain Radiotherapy on Neurocognitive Function Decline
ClinicalTrials.gov study NCT02504788. IPD Sharing: NO. Countries: 1. Publications: 2.
Stereotactic Radiotherapy of the Resection Cavity of Brain Metastases vs. Post-operative Whole-brain Radiotherapy
ClinicalTrials.gov study NCT03285932. IPD Sharing: NO. Countries: 1. Publications: 21.
Whole Brain Radiotherapy (WBRT) Versus Stereotactic Radiosurgery (SRS) for 4 Upto 10 Brain Metastases
ClinicalTrials.gov study NCT02353000. IPD Sharing: NO. Countries: 1. Publications: 6.
Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial
ClinicalTrials.gov study NCT03075072. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.