Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
3,650
datasets available to search
ShareScore release 0.9.0
Dataset results
3,650 results for “antibody”
Predictions of the SARS-CoV-2 B.1.1.529 Variant Spike Protein Receptor Binding Domain Structure and Neutralizing Antibody Interactions
<p>Using AlphaFold2 and HADDOCK, we have generated a predicted structure for the SARS-CoV-2 B.1.1.529 variant's Spike receptor binding domain and then predicted the binding interaction with neutralizing antibodies. This was performed to understand the potential structural changes in the receptor binding domain of B.1.1.529 and how this may affect vaccine efficacy through antibody interaction.</p>
Pre-vaccination and early B cell signatures of the antibody response to SARS-CoV-2 mRNA vaccine
<p>The data presented in Code repository for Kardava, L., Rachmaninoff, N., Lau, W. W., Buckner, C. M., Trihemasava, K., Blazkova, J., ... & Moir, S. (2022). Early human B cell signatures of the primary antibody response to mRNA vaccination. Proceedings of the National Academy of Sciences, 119(28), e2204607119.<a href="https://www.pnas.org/doi/epdf/10.1073/pnas.2204607119">https://www.pnas.org/doi/epdf/10.1073/pnas.2204607119</a> are made available here.</p> <p>All code to reproduce the figures can be found here: https://github.com/niaid/COVID_Vaccine_Bcells</p> <p><a href="https://zenodo.org/api/files/f93859d0-b062-4def-8b17-c0f21ee36f09/all_subjects_cd19_positive_and_keys.zip">all_subjects_cd19_positive_and_keys.zip</a> contains a CSV file of all CD19+ cells with flowSOM clusters shown. Accompanying files allow for matching of timepoint and subject information.</p> <p><a href="https://zenodo.org/api/files/f93859d0-b062-4def-8b17-c0f21ee36f09/All_subjects_FCS_files_deidentified.zip">All_subjects_FCS_files_deidentified.zip</a> contains the raw fcs files and is organized by timepoint and subject.</p>
Seroprevalence of anti-SARS-CoV-2 antibodies among communities in Bangui, Central African Republic
<p>Significance for public health</p> <p>This is a serological survey conducted in the Central Africa Republic among the general urban population not vaccinated against COVID-19. Its reveals a high cumulative level of immunity, thus indicating a significant degree of spread of SARS-CoV-2 in the population. More comprehensive studies to explore the impact of new variants on this quasi-herd-immunity as well as its effect on the immunity in people vaccinated against COVID-19.</p>
Peptide Mass Fingerprint Library of Monoclonal Murine anti-SARS-CoV-2 Antibodies
<p>The dataset contains fingerprints of monoclonal antibodies that can be used to identify the antibodies by using the open-source software ABID 2.0 <a href="https://bam.de/ABID">https://bam.de/ABID</a><br> More information can be found in the publication where this data was used to rapidly distinguish between 35 monoclonal murine Anti-SARS-CoV-2 antibodies: <a href="https://doi.org/10.3390/antib11020027">https://doi.org/10.3390/antib11020027 </a></p>
Risk of bias assessments for the Cochrane review 'SARS-CoV-2-neutralising monoclonal antibodies to prevent COVID-19'
<p>Risk of bias assessments and support for judgement with ROB 2 tool for the Cochrane Review: SARS-CoV-2-neutralising monoclonal antibodies to prevent COVID-19.</p>
Simulation of Receptor Binding Domain of SARS-CoV-2 spike protein (WT and variants) in complex with neutralizing antibodies.
<p>This repository contains the molecular dynamics trajectories of the SARS-CoV-2 Spike RBD bound to BD23 and B38 monoclonal antibodies. The simulations for the RBD only systems are also provided. The trajectories are available for the WT spike protein as well as for four different variants (alpha, beta, kappa and delta). The simulations of the RBD only system are propagated for 300 ns and for the RBD-Antibody complex for 500 ns. The trajectories are saved at 100 ps interval. The Steered MD simulation trajectories (WT_RBD_B38_SMD_1.dcd etc.) and collective variables files are also included (WT_RBD_B38_SMD_1.colvars.traj etc.). There are 5 SMD trajectories for each RBD antibody pair. The details of the simulation can be obtained from the preprint: https://doi.org/10.1101/2021.08.13.456317</p>
Molecular dynamics simulation trajectories of HIV protein gp120 in complex with antibody VRC01 and 30 of its Ala mutants
<p>This data set accompanies the publication by S. Conti, E. Lau, and V. Ovchinnikov entitled "On the rapid calculation of binding affinities for antigen and antibody design and affinity maturation simulations", to be published in the MDPI journal Antibodies. It contains molecular dynamics simulation trajectories of HIV protein gp120 in complex with antibody VRC01 and 30 of its Ala mutants, as described in the paper. The format of the trajectory files is CHARMM-compatible dcd. The files can be visualized with the program Visual Molecular Dynamics (VMD) (see paper by Humphrey et al. 1996, J. Molec. Graphics). The accompanying file "view" is a tcl-based script for VMD that can be executed in the Linux environment using: "vmd -e view", which will display the trajectory of the mutant specified by editing the first noncomment line of the script.<br> </p>
Dataset for the TBK1 antibody screening study
<p><strong>This antibody characterization dataset is related to the F1000 research article openly available at F1000Research.</strong></p> <p><em>This project contains the following underlying data included in a study aiming at characterization antibodies for the serine/threonine-protein kinase (TBK1) protein, encoded by the TBK1 gene. The original study is also available on the Zenodo YCharOS community (<a href="https://doi.org/10.5281/zenodo.6402968">https://doi.org/10.5281/zenodo.6402968</a>) and on BioRxiv (<a href="https://doi.org/10.1101/2022.06.03.494699">https://doi.org/10.1101/2022.06.03.494699</a>).</em></p> <p><em>File name is presented as "database number"_"company catalogue number".</em></p>
Data presented in Multi-trial analysis of HIV-1 envelope gp41-reactive antibodies among global recipients of candidate HIV-1 vaccines.
<p>This folder contains datasets analyzed in the manuscript:</p> <p>Multi-trial analysis of HIV-1 envelope gp41-reactive antibodies among global recipients of candidate HIV-1 vaccines.</p> <p>Frontiers in Immunology<br> Sec. Vaccines and Molecular Therapeutics<br> doi: 10.3389/fimmu.2022.983313</p>
Computationally profiling peptide:MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies
<p>Supporting datasets for preprint version of "Computationally profiling peptide:MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies".</p>
Fig. 4 T cell and antibodies responses acter three immunisations with T in SjTat-TPI facilitates adaptive T-cell responses and reduces hepatic pathology during Schistosoma japonicum infection in BALB/c mice
Fig. 4 T cell and antibodies responses acter three immunisations with T-TPI + IFA, TPI + IFA, IFA and PBS. a and b: Percentages oc CD3+CD4+IFN-γ+ (Th1) and CD3+CD8+IFN-γ+ (Tc1) gated crom CD3+ cells analvsed bv FACS. c. IgG, IgG1 and IgG2a lesels in mice sera were detected. Data are presented as the means ± SEM crom eight mice in each group. (*P <0.05; **P <0.01)
Dataset: ImmunoPrecise Antibodies Ltd. (IPA) Stock Performance
This dataset provides historical stock market performance data for specific companies. It enables users to analyze and understand the past trends and fluctuations in stock prices over time. This information can be utilized for various purposes such as investment analysis, financial research, and market trend forecasting.
Annotation of the non-canonical translatome reveals that CHO cell microproteins are a new class of therapeutic antibody drug product impurity
<p>3,681 novel Chinese hamster proteoforms (derived from uORFs, ouORFs and ORFs encoded on NCBI annotated non-coding RNAs).</p>
Dataset for the Synaptotagmin-1 antibody screening study
<p><strong>This antibody characterization dataset is related to the F1000 research article openly available at F1000Research.</strong></p> <p><em>The dataset presented contains the following underlying raw data for study which evaluated twelve commercial antibodies against Synaptotagmin-1 in western blot, immunoprecipitation, immunofluorescence and flow cytometry. The original study is also accessible on the YCharOS Zenodo community (<a href="https://doi.org/10.5281/zenodo.12666747">https://doi.org/10.5281/zenodo.12666747</a>).</em></p> <p><em>The Dataset is in the format of a zip file. Once downloaded, please expand the zip file to access the folders containing the underlying data for Western blot (Wb), immunoprecipitation (IP) and immunofluorescence (IF).</em></p>
Fig. 3 in Seroprevalence of Borrelia burgdorferi antibodies in white-tailed deer from Texas
Fig. 3. Assays used to demonstrate reactivity to Borrelia burgdorferi antigens in white-tailed deer serum samples. (A.) The molecular weight marker (Mk) showing estimated molecular weights of Borrelia antigens (Bb). (B.) From left to right, negative control samples (1—5) and samples highly sero-reactive (6—12). The three immunoassays used were ELISA, standardized western immunoblot (WB) and Marblot (MB) assays.
Fig. 2 in Seroprevalence of Borrelia burgdorferi antibodies in white-tailed deer from Texas
Fig. 2. Optical density values of the white-tailed deer (WTD) serum samples analyzed with indirect ELISA for Borrelia burgdorferi. (A.) ELISA data from 109 WTD serum samples used as negative controls, collected from 2003 to 2015. (B.) ELISA data from 1384 WTD serum samples collected from 2001 to 2013. The dashed line denotes the cut off value used in this study. The samples above this line were analyzed with standardized western immunoblot assay.
Fig. 4 in Seroprevalence of Borrelia burgdorferi antibodies in white-tailed deer from Texas
Fig. 4. Confirmed human Lyme Disease cases in Texas from 2000 to 2013 reported to the CDC (www.cdc.com).
Fig. 5 in Seroprevalence of Borrelia burgdorferi antibodies in white-tailed deer from Texas
Fig. 5. White-tailed deer (WTD) population density in Texas eco-regions from 2005 to 2013. This graph is a representation of WTD population density statewide in Texas; in two counties (Travis and Williamson) where sero-reactive samples, and negative control samples for Borrelia burgdorferi antibodies were found.
Fig. 1. Texas map showing 14 in Seroprevalence of Borrelia burgdorferi antibodies in white-tailed deer from Texas
Fig. 1. Texas map showing 14 counties in which white-tailed deer (WTD) were sampled for Borrelia burgdorferi antibodies from 2001 to 2015. Blue counties: samples negative by ELISA and standardized western immunoblot; Gray counties: negative control samples; Yellow counties: samples sero-reactive by standardized western immunoblot assay (Travis and Williamson counties). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
Fig. 3. Predicted relationship between pre-treatment H in Age affects antibody levels and anthelmintic treatment efficacy in a wild rodent
Fig. 3. Predicted relationship between pre-treatment H. polygyrus burden and post-treatment H. polygyrus-specific IgG1 titre for A) juvenile mice, B) young adult mice and C) adult mice. ELW was split into equal thirds to group mice into juvenile (9.2 μg-15.8 μg), young adult (15.8 μg-22.4 μg) or adult mice (22.4 μg- 29.0 μg).
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.