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3,790 results for “anxiety”
Gene associations with human anxiety (MAGMA)
<p>Anxiety disorders are common and can be debilitating, with effective treatments remaining hampered by an incomplete understanding of the underlying genetic etiology. Improvements have been made in understanding the genetic influences on mouse behavioral models of anxiety, yet it is unclear the extent to which genes identified in these experimental systems contribute to genetic variation in human anxiety phenotypes. Leveraging new and existing large-scale human genome-wide association studies, we tested whether sets of genes previously identified in mouse anxiety-like behavior studies contribute to a range of human anxiety disorders. When tested as individual genes, thirteen mouse-identified genes were associated with human anxiety phenotypes, suggesting an overlap of individual genes contributing to both mouse models of anxiety-like behaviors and human anxiety traits. When genes were tested as sets, we did identify fourteen significant associations between mouse gene sets and human anxiety, but the majority of gene sets showed no significant association with human anxiety phenotypes. These few significant associations indicate a need to identify and develop more translatable mouse models by identifying sets of genes that 'match' between model systems and specific human phenotypes of interest. We suggest that continuing to develop improved behavioral paradigms and finer-scale experimental data, for instance from individual neuronal subtypes or cell-type-specific expression data, is likely to improve our understanding of the genetic etiology and underlying functional changes in anxiety disorders.</p>
Internet-based interdisciplinary therapeutic group for perinatal anxiety and depression - a randomized pilot study during COVID-19
<p><strong>Abstract</strong>:</p> <p><strong>Background</strong>: Recent years have seen growing interest in the impact that stress and depressive/anxiety symptomatology have on mothers, fetal development, the mother-baby relationship and infant development. Depressed mothers spend less time making eye-contact with their babies, and caressing and talking to them, which can cause delays in cognitive and emotional development. Early interventions promote reductions in mothers’ stress and anxiety symptoms along with improvements in their ability to read infant cues appropriately. Group perinatal care and internet-based therapeutic interventions were essential during the Covid period and telemedicine ensures continuity of contact with high-risk populations. The aim of this novel study was to assess the effects of interdisciplinary online therapeutic group in at-risk mothers and babies during the Covid-19 pandemic in a disadvantaged neighborhood in Barcelona (Spain).</p> <p><strong>Method</strong>: An interdisciplinary team offered gestating women and mothers comprehensive care in a protective environment in a Primary Health Care Center. Pregnant women and new mothers were screened to detect depressive-anxiety symptomatology through EPDS/STAI questionnaires. A total of 135 babies were born from March 2020 to June 2021, during the pandemic, and 72 women met high-risk criteria for anxiety or depression. Some 37 pregnant women and mother-baby dyads were treated in the therapeutic group and compared with 27 women randomly selected from the control group, who received treatment as usual. A blinded pediatric follow-up was established when the babies were 6 months old to monitor their development through the Llevant Scale. The course of the mothers’ symptomatology was also assessed.</p> <p><strong>Results</strong>: We obtained a significant decrease in depressive-anxiety symptomatology (EPDS p=0.000; STAI state p=0.015 and STAI trait p=0.001 at 6 months of life) in the therapeutic group compared with controls. Follow-up at 6 months demonstrated significant differences between groups in assessment of the babies’ development (manipulation p=0.003; language p=0.000; sociability p=0.000). The therapeutic group showed no difficulties in any areas of development.</p> <p><strong>Conclusions: </strong>Interdisciplinary online therapeutic group helps to ensure healthy development of the baby and reduction of the mothers’ depressive-anxiety symptomatology. Future research should involve larger samples to explore the impact of online group interventions in both mothers and babies.</p> <p><strong>Trial registration: </strong>The study is registered at Jordi Gol i Gurina Foundation number 21/276-P.</p>
Rocking math at school with hypnosis: Effective reduction of math test anxiety with an audio hypnosis intervention in a school setting
<p>Math as a school subject causes anxiety in many students. Previous results show that male and female students do not differ in their math performance. However, female students are more affected by math anxiety than male students, so that they might hesitate pursuing STEM careers. Actively<br> addressing math anxiety requires an intervention that reduces anxiety, changes attitude, and provides positive experiences. Hypnosis interventions are particularly suitable for this. Therefore, we developed a 30-minutes audio-hypnosis intervention and tested its effectiveness in this study. We randomly assigned students into an intervention group (N = 29) and a control group (N = 38). All students performed two real math tests at school. The intervention group listened at least once to the hypnosis audio intervention between both math tests. Immediately before each math test, we assessed state-math anxiety (measured with STAI-S). To investigate performance differences, we<br> analyzed students’ math performance scores in both math tests. Our results show that the hypnosis intervention led to a significant reduction in state-math anxiety, t(28) = 2.42, p = .022, Cohen`s dz = 0.45. Math performance did not differ significantly between math tests in the intervention group. Female students generally had higher trait math anxiety (as measured by SIMA scale) and showed a greater reduction in state math anxiety due to the hypnosis intervention, t(18) = 2.86, p = .010, Cohen`s dz = 0.66, compared to male students. It is possible that reduced state math anxiety could result in improved math performance in the long run. Overall, we conclude that our hypnosis intervention reduces math anxiety, especially in female students. Therefore, it is a promising method to promote especially females at an early point in their career and encourage them to choose STEM pathways. The final goal would be to establish hypnosis-based interventions at school encouraging students to activate their resources and develop their potential in all fields.</p>
Analysis and Prediction of Athlete's Anxiety State based on Artificial Intelligence
<p>This is the data set used for the implementation of Project Analysis and Prediction of Athlete's Anxiety State based on Artificial Intelligence</p>
To all people suffering with anxiety, and the rest as well.
<p>Published in annual review of silliness. <br> <br> https://www.youtube.com/watch?v=NATej3MkGUA</p>
To all people suffering with anxiety, and the rest as well.
<p>Published in annual review of silliness: Special issue on Spanish Inquisition. <br> <br> https://www.youtube.com/watch?v=NATej3MkGUA</p>
data and code for "Depression and social anxiety in relation to problematic TikTok use severity: The mediating role of boredom proneness and distress intolerance "
<p>data and code for the paper titled "Depression and social anxiety in relation to problematic TikTok use severity: The mediating role of boredom proneness and distress intolerance", to be published on Computers in Human Behavior.</p> <p> </p> <p> </p>
A Pilot Randomized Controlled Trial of Distance Laughter Therapy for Mothers' Level of Depression, Anxiety, and Parental Stress during the COVID-19 Pandemic
<p>Presented here are both quantitative and qualitative datasets from a study titled 'A Pilot Randomized Controlled Trial of Distance Laughter Therapy for Mothers’ Level of Depression, Anxiety, and Parental Stress during the COVID-19 Pandemic.' The COVID-19 pandemic has necessitated significant lifestyle modifications globally, leading to heightened psychological stressors, notably depression and anxiety. Concurrently, the exigencies of parental care have escalated, thereby amplifying the risk of caregiver exhaustion and potential child maltreatment. This study sought to assess the efficacy and feasibility of utilizing distance laughter therapy for mothers who are looking after young children during these challenging times. The primary objective was to alleviate symptoms of depression, anxiety, and parental stress.</p>
Predicting Mathematics Anxiety and Achievement: Unveiling the Significance of Student and Teacher Attributes through Hierarchical Linear Modeling
<p>This study aimed to determine the predictive power of student and teacher characteristics on students' math anxiety and achievement.</p>
Adverse childhood events and clinical manifestation of anxiety symptoms in Greek adolescents during COVID-19 pandemic
<p><strong>Background: </strong>Adverse Childhood Experiences (ACEs) are linked to the development of Anxiety in Adolescence. According to recent studies, the pandemic COVID-19 is a novel ACE that has increased Anxiety among adolescents. This study aims to investigate the relationship between Adverse Childhood Experiences (ACEs) and COVID-19 in the development of Anxiety in Adolescence. <strong>Methods: </strong>A cross-sectional study with a community sample of 248 boys and girls aged 12 to 15 years (Mean: 13.50 years) from five High Schools in Eastern Attica were conducted. A total of four questionnaires were used: 1) Demographic Questionnaire, 2) State-Trait-Anxiety-Inventory for Children – STAIC, 3) Adverse Childhood Experiences Scale, and 4) COVID-19 Impact Scale. <strong>Results: </strong>The results demonstrated a strong correlation between the total number of adverse childhood experiences (ACEs) and Anxiety (Trait and State) in adolescence (Trait Anxiety: rho=.37, p0.001; State Anxiety: rho=.29, p0.001). Girls scored substantially higher on Trait Anxiety (U = 4353, p 0.001) and State Anxiety (U = 5822.5, p = 0.014) than boys. Girls also demonstrated more significant Anxiety than boys. The number of adverse childhood experiences was found to be significantly related to the impact of COVID-19 (=0.025, p 0.001). <strong>Conclusions: </strong>The present study's findings can be used to design and implement future effective, preventive, and therapeutic programs for adolescents with anxiety symptoms who were exposed to a variety of Adverse Childhood Experiences and the COVID-19 pandemic during their adolescence.</p>
Attention Bias Modification Training for Child Anxiety CBT Nonresponders
ClinicalTrials.gov study NCT01819311. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Computer-Delivered Intervention for Individuals With Obesity and Elevated Anxiety Sensitivity
ClinicalTrials.gov study NCT03917901. IPD Sharing: NO. Countries: 1. Publications: 0.
Antiglucocorticoid Therapy for Cognitive Impairment in Late-life Anxiety Disorders
ClinicalTrials.gov study NCT01333098. IPD Sharing: NO. Countries: 1. Publications: 1.
SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)
ClinicalTrials.gov study NCT01470469. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy and Safety Study of Seroquel SR in the Treatment of Generalised Anxiety Disorder
ClinicalTrials.gov study NCT00389064. IPD Sharing: Not stated. Countries: 5. Publications: 1.
Telephone Psychotherapy for Late-Life Generalized Anxiety Disorder (GAD)
ClinicalTrials.gov study NCT01259596. IPD Sharing: NO. Countries: 1. Publications: 2.
Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
ClinicalTrials.gov study NCT01563003. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Pregabalin in the Treatment of Patients With Generalized Anxiety Disorder (GAD).
ClinicalTrials.gov study NCT00413010. IPD Sharing: Not stated. Countries: 8. Publications: 1.
Effects of Sleep Hygiene Education and Progressive Relaxation Exercise on Anxiety, Sleep Quality and Glycemic Control in Diabetic Patients
ClinicalTrials.gov study NCT06960408. IPD Sharing: NO. Countries: 0. Publications: 0.
Efficacy of an Internet-based Intervention for Dental Anxiety
ClinicalTrials.gov study NCT03680755. IPD Sharing: NO. Countries: 1. Publications: 10.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.