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364
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ShareScore release 0.9.0
Dataset results
364 results for “breast tissue”
Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue
ClinicalTrials.gov study NCT01944215. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Magnetic Resonance (MR) Spectroscopy of Breast Cancer Tissue
ClinicalTrials.gov study NCT00184210. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Data from: Fusion transcript discovery in formalin-fixed paraffin-embedded human breast cancer tissues reveals a link to tumor progression
The identification of gene fusions promises to play an important role in personalized cancer treatment decisions. Many rare gene fusion events have been identified in fresh frozen solid tumors from common cancers employing next-generation sequencing technology. However the ability to detect transcripts from gene fusions in RNA isolated from formalin-fixed paraffin-embedded (FFPE) tumor tissues, which exist in very large sample repositories for which disease outcome is known, is still limited due to the low complexity of FFPE libraries and the lack of appropriate bioinformatics methods. We sought to develop a bioinformatics method, named gFuse, to detect fusion transcripts in FFPE tumor tissues. An integrated, cohort based strategy has been used in gFuse to examine single-end 50 base pair (bp) reads generated from FFPE RNA-Sequencing (RNA-Seq) datasets employing two breast cancer cohorts of 136 and 76 patients. In total, 118 fusion events were detected transcriptome-wide at base-pair resolution across the 212 samples. We selected 77 candidate fusions based on their biological relevance to cancer and supported 61% of these using TaqMan assays. Direct sequencing of 19 of the fusion sequences identified by TaqMan confirmed them. Three unique fused gene pairs were recurrent across the 212 patients with 6, 3, 2 individuals harboring these fusions respectively. We show here that a high frequency of fusion transcripts detected at the whole transcriptome level correlates with poor outcome (P<0.0005) in human breast cancer patients. This study demonstrates the ability to detect fusion transcripts as biomarkers from archival FFPE tissues, and the potential prognostic value of the fusion transcripts detected.
Study of the Safety of MRI Scans in People Who Have Breast Tissue Expanders After Mastectomy
ClinicalTrials.gov study NCT04769960. IPD Sharing: YES. Countries: 1. Publications: 0.
Comparison of One-port and Two-port Tissue Expanders for Breast Reconstruction
ClinicalTrials.gov study NCT02725801. IPD Sharing: NO. Countries: 1. Publications: 0.
ciNPT in Autologous Abdominal Tissue Breast Reconstruction
ClinicalTrials.gov study NCT04985552. IPD Sharing: Not stated. Countries: 0. Publications: 18.
Cell Lines From High-Risk Breast Tissue
ClinicalTrials.gov study NCT00032201. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Study to Evaluate the Effect of Sulforaphane in Broccoli Sprout Extract on Breast Tissue
ClinicalTrials.gov study NCT00982319. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement
ClinicalTrials.gov study NCT07220967. IPD Sharing: YES. Countries: 1. Publications: 0.
Proof of Principle Trial to Determine if Nutritional Supplement Conjugated Linoleic Acid (CLA) Can Modulate the Lipogenic Pathway in Breast Cancer Tissue
ClinicalTrials.gov study NCT00908791. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The SeriScaffold® Use in Reconstruction Post Market Study for Tissue Support and Repair in Breast Reconstruction Surgery in Europe
ClinicalTrials.gov study NCT01389232. IPD Sharing: NO. Countries: 4. Publications: 0.
A Study to Investigate the Effects of Tibolone (Livial®) on Breast Tissue in Postmenopausal Women With Breast Cancer (Study 32971)(P06469)
ClinicalTrials.gov study NCT00725374. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Gene Expression in Tumor Tissue From Women Undergoing Surgery for Breast Cancer or Core Biopsy of the Breast
ClinicalTrials.gov study NCT00898937. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study to Evaluate Changes in Human Breast Cancer Tissue Following Short-Term Use of Darolutamide
ClinicalTrials.gov study NCT03004534. IPD Sharing: UNDECIDED. Countries: 3. Publications: 0.
Biomarkers in Tissue Samples From Patients With Newly Diagnosed Breast Cancer Treated With Zoledronic Acid
ClinicalTrials.gov study NCT01409811. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Pilot Study of Oxytocin and microRNA Identification in NAF, Serum, and Tissue in Women With Breast Cancer
ClinicalTrials.gov study NCT02127073. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Trial of 4-Hydroxytamoxifen (4-OHT) Gel in Women Aimed at Reducing Dense Breast Tissue
ClinicalTrials.gov study NCT03199963. IPD Sharing: NO. Countries: 3. Publications: 0.
Local Antibiotic Concentrations With Tissue Expanders in Breast Reconstruction
ClinicalTrials.gov study NCT07339215. IPD Sharing: NO. Countries: 1. Publications: 0.
Rosuvastatin to Lower Circulating Tissue Factor Bearing Microparticles in Metastatic Breast Cancer
ClinicalTrials.gov study NCT01299038. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dose Escalation Study MORAb-066 Targeting Tissue Factor (TF)-Expressing Malignancies Including Breast, Pancreatic, Colorectal, NSCLC
ClinicalTrials.gov study NCT01761240. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.