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Figure 4 in First record of Poecilochirus mrciaki Mašán, 1999 (Acari, Parasitidae) and its phoretic carriers in the Iberian peninsula
Figure 4 Percentage of Poecilochirus mrciaki mites per stage of decomposition (F, fresh; Bl, Bloated; Ac, Active decay; Ad, Advance decay; D, Dry)
Figure 3 in First record of Poecilochirus mrciaki Mašán, 1999 (Acari, Parasitidae) and its phoretic carriers in the Iberian peninsula
Figure 3 Corresponding analysis of the association between insect carriers transporting Poecilochirus mrciaki and stages of decomposition. P. mrciaki shows a clear association with Coleoptera visiting carcasses. Axis 1 44%, Axis 2 38%. (AST: Anoplotrupes stercorosus, CAL: Calliphoridae, CMA: Creophilus maxilosus, NLI: Necrodes littoralis, NVE: Nicrophorus vespilloides, TPY: Trypocopris pyrenaeus, DIP: unidentified Diptera).
Figure 6 in First record of Poecilochirus mrciaki Mašán, 1999 (Acari, Parasitidae) and its phoretic carriers in the Iberian peninsula
Figure 6 Stacked chart (%) of number of Poecilochirus mrciaki brought by each insect at each stage of decomposition. (AST: Anoplotrupes stercorosus, CAL: Calliphoridae, CMA:Creophilus maxilosus,NLI: Necrodes littoralis, NVE: Nicrophorus vespilloides, TPY: Trypocopris pyrenaeus, DIP: unidentified Diptera).
Elevated urine BMP phospholipids in LRRK2 and VPS35 mutation carriers with and without Parkinson's disease
<p><strong>Participant demographic and clinical characteristics, and urine BMP phospholipid levels. </strong></p> <p>For each participant, sample collection site is provided as: BCN (Barcelona), VIE (Vienna), DND (Dundee), or SSB (San Sebastian). Also provided are age at study participation, age at PD diagnosis (where applicable), sex (M, for male, and F, for female), experimental group (control, iPD –idiopathic PD –, LRRK2 G2019S, LRRK2 R1441G/C, VPS35 D620N, GBA, or other), and PD status (NMC for non-manifesting mutation carriers, or PD). Values for all measured BMP species presented as ng of BMP per mg of creatinine are provided. Additionally, urine creatinine (mg/ml) and non-normalized BMP levels are provided. BQL designates BMP levels that were below quantification level and NM designates values that were not measured for a particular individual.</p>
Hot carrier extraction from 2D semiconductor photoelectrodes
<p>Hot carrier-based energy conversion systems could double the efficiency of conventional solar energy technology or drive photochemical reactions that would not be possible using fully thermalized, "cool" carriers, but current strategies require expensive multi-junction architectures. Using an unprecedented combination of photoelectrochemical and in situ transient absorption spectroscopy measurements, we demonstrate ultrafast (<50 fs) hot exciton and free carrier extraction under applied bias in a proof-of-concept photoelectrochemical solar cell made from earth-abundant and potentially inexpensive monolayer (ML) MoS<sub>2</sub>. Our approach facilitates ultrathin 7 Å charge transport distances over 1 cm<sup>2</sup> areas by intimately coupling ML-MoS<sub>2</sub> to an electron-selective solid contact and a hole-selective electrolyte contact. Our theoretical investigations of the spatial distribution of exciton states suggest greater electronic coupling between hot exciton states located on peripheral S atoms and neighboring contacts likely facilitates ultrafast charge transfer. Our work delineates future 2D semiconductor design strategies for practical implementation in ultrathin photovoltaic and solar fuels applications.</p>
Hot carrier extraction from 2D semiconductor photoelectrodes
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Data for [Identification of paleomagnetic remanence carriers in ca. 3.47 Ga dacite from the Duffer Formation, the Pilbara Craton]
<p>Data used in the manuscript [Identification of paleomagnetic remanence carriers in ca. 3.47 Ga dacite from the Duffer Formation, the Pilbara Craton] by Usui et al., Physics of the Earth and Planetary Interiors.</p>
Eclipse2017 17-hour CSV quadrature, in-phase WWVB carrier in one-second increments
<p>Boxcar-integrated I&Q data sets of WWVB (60 kHz) received with magnetic loop antenna at 43.21N, 79.89W (Hamilton, ON). Three data files start at 09:00:00 UTC. on Aug 20, Aug 21, Aug 22, 2017. Each file spans seventeen hours.</p> <p>Each I&Q boxcar data point represents average WWVB carrier integrated over the one-second period starting with WWVB's BPSK phase-transition point, one-hundred milliseconds after start-of-second. The 60 kHz carrier downconverter oscillator is a Valpey-Fisher VF150 crystal oscillator which is free-running. Its phase and frequency vary with time and temperature. It is possible to determine WWVB's legacy AM timecodes from <span class="math-tex">\(amplitude = \sqrt{inphase^2+ quadrature^2}\)</span></p> <p>File format is CSV text compatible, quadrature delimited by ASCII space '0x20' from in-phase. Quadrature and In-phase data are signed decimal integers lying in all four phase quadrants.</p>
miRNA counts identified by RNA seq in the caudate nucleus of patients neuropathologically diagnosed with late-onset Alzheimer's disease (non-carriers and carriers of intermediate expansions in the HTT gene) and healthy subjects.
<p>These data include the raw miRNA counts identified by RNA-seq in <em>post mortem</em> caudate nucleus samples. Samples with identifier <strong>A</strong> belong to patients with a neuropathological diagnosis of late-onset Alzheimer's disease. Group <strong>B</strong> samples belong to patients with the same neuropathological diagnosis, but carrying CAG expansions in the intermediate range (27-35 CAG) in the <em>HTT</em> gene. Finally, group <strong>C </strong>samples belong to healthy subjects without neuropathological diagnosis. </p> <p> </p>
Carriere du Ru - Salle de Teufs
Photogrammétrie de la Salle de Teufs de la carrière du Ru. Modèle simplifiée. Source: Objaverse 1.0 / Sketchfab
Figures and datasets of paper titled "Bulk carrier lifetime surpassing 600 us in Upgraded Metallurgical-grade Silicon multicrystalline wafers after Phosphorus Diffusion Gettering"
<p>Datasets and figures of paper titled "Figures and datasets of paper titled "Bulk carrier lifetime surpassing 600 us in Upgraded Metallurgical-grade Silicon multicrystalline wafers after Phosphorus Diffusion Gettering" published in arXiv (<a href="https://arxiv.org/abs/2111.13522">https://arxiv.org/abs/2111.13522</a>).</p>
Data accompanying "Integrated Dual-Laser Photonic Chip for High-Purity Carrier Generation Enabling Ultrafast Terahertz Wireless Communications"
<p>This dataset contains measurement data for the results presented in "Integrated Dual-Laser Photonic Chip for High-Purity Carrier Generation Enabling Ultrafast Terahertz Wireless Communications".</p>
Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer
<p><span><span><span><span><strong><em>Objective</em></strong>: The mitochondrial pyruvate carrier (MPC) has emerged as a promising drug target for metabolic disorders, including non-alcoholic steatohepatitis and diabetes, metabolically dependent cancers and neurodegenerative diseases. A range of structurally diverse small molecule inhibitors have been proposed but the nature of their interaction with MPC is not understood. Moreover, the composition of the functional human MPC is still debated. The goal of this study was to characterize the human MPC protein <em>in vitro</em>, to understand the chemical features that determine binding of structurally diverse inhibitors and to develop novel higher affinity ones.</span></span></span></span></p> <p><span><span><span><span><strong><em>Results</em></strong>: We have determined that the functional unit of human MPC is a hetero-dimer. We have compared all different classes of MPC inhibitors to find that three closely arranged hydrogen bond acceptors followed by an aromatic ring are shared characteristics of all inhibitors and represent the minimal requirement for high potency. We also demonstrate that high affinity binding is not attributed to covalent bond formation with MPC cysteines, as previously proposed. Following the basic pharmacophore properties, we identify 14 new inhibitors of MPC, one outperforming compound UK5099 by tenfold. Two of them are the commonly prescribed drugs entacapone and nitrofurantoin, suggesting an off-target mechanism associated with their adverse effects. </span></span></span></span></p> <p><span><span><span><span><strong><em>Conclusion</em></strong>: This work defines the composition of human MPC and the essential MPC inhibitor characteristics. In combination with the functional assays we describe, this new understanding will accelerate the development of clinically relevant MPC modulators.</span></span></span></span></p>
Muonic Force Carriers
<p>The datasets contain Muonic Force Carriers (MFC) events generated with Monte Carlo simulations. They describe the scattering of an incoming muon and a target nucleus of the detector material of the ATLAS detector, which produces an outgoing muon, the outgoing target and a MFC. The datasets are given in function of the energy of the incoming muon, ranging from 50 to 200 GeV, in step of 25 GeV. The shape of each dataset is of (100'000,5,3), where 100'000 is the number of events, 5 corresponds to the different particle (incoming muon, target at rest, outgoing muon, outgoing target, MFC), and 3 to the different features (energy, transversal momentum, pseudorapidity).</p>
DATASET_Effect Of Electronic Doping And Traps On Carrier Dynamics In Tin Halide Perovskites_BOLLA_v1
<p>This document contains the data supporting the peer-reviewed publication : Effect of electronic doping and traps on carrier dynamics in tin halide perovskites by Treglia et al. (<em>Materials Horizons</em>, 2022, <strong>9</strong>, 1763 - 1773) .</p> <p> </p>
Supplemental information data from: "Evidence for amorphous sulfates as the main carrier of soil hydration in Gale crater, Mars"
<p>This dataset includes the target name and chemical composition of each ChemCam sequence used in the above-mentioned article. The quantification for each ChemCam spectrum in the soils of the Bradbury, Rocknest and Yellowknife Bay area are in percentage mass fractions (wt.%) for most major oxides (i.e., SiO2, TiO2, Al2O3, FeOT , MgO, CaO, Na2O, K2O). Sulfur and hydrogen abundances are expressed respectively in peak area (normalized) and ICA H scores.</p>
M113A1 Troop Carrier (Raw Scan)
An armored personnel carrier located on museum grounds at Fort Benning, GA. Orginally developed in the 1960s as a mechanized troop carrier, these metal boxes have remained in service ever since. Processed from 113 photos taken with a Canon Rebel EOS XSI Source: Objaverse 1.0 / Sketchfab
Hop Flower Supercritical Carbon Dioxide Extracts Coupled with Carriers with Solubilizing Properties—Antioxidant Activity and Neuroprotective Potential
<p>Article, Dataset for article</p> <p> </p> <h1>Hop Flower Supercritical Carbon Dioxide Extracts Coupled with Carriers with Solubilizing Properties—Antioxidant Activity and Neuroprotective Potential</h1> <p> </p> <h2>Abstract</h2> <div><span>Lupuli flos</span> shows many biological activities like antioxidant potential, extended by a targeted effect on selected enzymes, the expression of which is characteristic for neurodegenerative changes within the nervous system. <span>Lupuli flos</span> extracts (LFE) were prepared by supercritical carbon dioxide (scCO<sub>2</sub>) extraction with various pressure and temperature parameters. The antioxidant, chelating activity, and inhibition of acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and tyrosinase by extracts were studied. The extracts containing ethanol were used as references. The most beneficial neuroprotective effects were shown by the extract obtained under 5000 PSI and 50 °C. The neuroprotective effect of active compounds is limited by poor solubility; therefore, carriers with solubilizing properties were used for scCO<sub>2</sub> extracts, combined with post-scCO<sub>2</sub> ethanol extract. Hydroxypropyl-β-cyclodextrin (HP-β-CD) in combination with magnesium aluminometasilicate (Neusilin US2) in the ratio 1:0.5 improved dissolution profiles to the greatest extent, while the apparent permeability coefficients of these compounds determined using the parallel artificial membrane permeability assay in the gastrointestinal (PAMPA GIT) model were increased the most by only HP-β-CD.</div> <div> <div> <div>Keywords: </div> <a href="https://www.mdpi.com/search?q=neuroprotection">neuroprotection</a>; <a href="https://www.mdpi.com/search?q=hop+strobile">hop strobile</a>; <a href="https://www.mdpi.com/search?q=inhibition+of+enzymes">inhibition of enzymes</a>; <a href="https://www.mdpi.com/search?q=xanthohumol">xanthohumol</a></div> </div>
Co-Dispersion Delivery Systems with Solubilizing Carriers Improving the Solubility and Permeability of Cannabinoids (Cannabidiol, Cannabidiolic Acid, and Cannabichromene) from Cannabis sativa (Henola Variety) Inflorescences
<p>Article, Dataset for article</p> <p> </p> <h2>Abstract</h2> <div>Cannabinoids: cannabidiol (CBD), cannabidiolic acid (CBDA), and cannabichromene (CBC) are lipophilic compounds with limited water solubility, resulting in challenges related to their bioavailability and therapeutic efficacy upon oral administration. To overcome these limitations, we developed co-dispersion cannabinoid delivery systems with the biopolymer polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol (Soluplus) and magnesium aluminometasilicate (Neusilin US2) to improve solubility and permeability. Recognizing the potential therapeutic benefits arising from the entourage effect, we decided to work with an extract instead of isolated cannabinoids. <span>Cannabis sativa</span> inflorescences (Henola variety) with a confirming neuroprotective activity were subjected to dynamic supercritical CO<sub>2</sub> (scCO<sub>2</sub>) extraction and next they were combined with carriers (1:1 mass ratio) to prepare the co-dispersion cannabinoid delivery systems (HiE). In vitro dissolution studies were conducted to evaluate the solubility of CBD, CBDA, and CBC in various media (pH 1.2, 6.8, fasted, and fed state simulated intestinal fluid). The HiE-Soluplus delivery systems consistently demonstrated the highest dissolution rate of cannabinoids. Additionally, HiE-Soluplus exhibited the highest permeability coefficients for cannabinoids in gastrointestinal tract conditions than it was during the permeability studies using model PAMPA GIT. All three cannabinoids exhibited promising blood-brain barrier (BBB) permeability (P<sub>app</sub> higher than 4.0 × 10<sup>−6</sup> cm/s), suggesting their potential to effectively cross into the central nervous system. The improved solubility and permeability of cannabinoids from the HiE-Soluplus delivery system hold promise for enhancement in their bioavailability.</div> <div> <div> <div>Keywords: </div> <a href="https://www.mdpi.com/search?q=cannabidiol">cannabidiol</a>; <a href="https://www.mdpi.com/search?q=cannabidiolic+acid">cannabidiolic acid</a>; <a href="https://www.mdpi.com/search?q=cannabichromene">cannabichromene</a>; <a href="https://www.mdpi.com/search?q=cannabis">cannabis</a>; <a href="https://www.mdpi.com/search?q=solubility">solubility</a>; <a href="https://www.mdpi.com/search?q=permeability">permeability</a></div> </div>
Data from: Carrier density crossover and quasiparticle mass enhancement in a doped 5d Mott insulator
<p>High-temperature superconductivity in cuprates emerges upon doping the parent Mott insulator. Key features of the low-doped cuprate superconductors include an effective carrier density that tracks the number of doped holes, the emergence of an anisotropic pseudogap that is characterized by disconnected Fermi arcs, and the closure of the gap at a critical doping level. In Sr<sub>2</sub>IrO<sub>4</sub>, a spin–orbit-coupled Mott insulator often regarded as a 5<em>d </em>analog of the cuprates, surface probes have also revealed the emergence of an anisotropic pseudogap and Fermi arcs under electron doping. However, neither the corresponding critical doping nor the bulk signatures of pseudogap closure have yet been observed. Here we demonstrate that electron-doped Sr<sub>2</sub>IrO<sub>4</sub> exhibits a critical doping level with a marked crossover in the effective carrier density at low temperatures. This is accompanied by a five-orders-of-magnitude increase in conductivity and a sixfold enhancement in the electronic-specific heat. These collective findings resemble the bulk pseudogap phenomenology in cuprates. However, given that electron-doped Sr<sub>2</sub>IrO<sub>4</sub> is non-superconducting, it suggests that the pseudogap may not be a state of precursor pairing. Therefore, our results narrow the search for the key ingredient underpinning the formation of the superconducting condensate in doped Mott insulators.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.